4M1J

Crystal structure of Pseudomonas aeruginosa PvdQ in complex with a transition state analogue

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity
A	0016811	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
A	0017000	biological_process	antibiotic biosynthetic process
C	0016787	molecular_function	hydrolase activity
C	0017000	biological_process	antibiotic biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE B0S C 801

Chain	Residue
C	SER217
C	HIS239
C	PHE240
C	THR285
C	VAL286
C	VAL374
C	TRP378
C	ASN485
C	HOH1011

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 802

Chain	Residue
C	LEU259
C	ASP260
C	ASN382
C	HOH942
C	HOH943

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL C 803

Chain	Residue
A	PRO98
A	ILE101
C	PRO256
C	GLY257
C	HIS337
C	HOH1095
C	HOH1256

---

site_id	AC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL C 804

Chain	Residue
A	GOL205
A	HOH427
C	TYR344
C	GLY345
C	PRO346
C	LEU364
C	ARG365
C	ASP366
C	LEU369
C	HOH1002
C	HOH1149

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL C 805

Chain	Residue
C	ARG365
C	ALA454
C	TRP455
C	ARG457
C	ALA464
C	GLY465

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL C 806

Chain	Residue
A	GLU72
A	SER91
A	ALA92
A	ARG168
C	PRO241
C	ASN243
C	GLY244
C	ALA245
C	MET246

---

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL C 807

Chain	Residue
C	THR372
C	ARG373
C	ALA462
C	GLN463
C	HOH976
C	HOH992
C	HOH1013
C	HOH1039
C	HOH1136

---

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL C 808

Chain	Residue
C	PHE596
C	ALA597
C	GLU598
C	LEU599
C	GLY601
C	ALA602
C	TRP603
C	HOH1015

---

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL C 809

Chain	Residue
C	ILE255
C	PRO256
C	GLY257
C	ARG258
C	LEU259
C	ASP260
C	HOH1118
C	HOH1229

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL C 810

Chain	Residue
C	GLN498
C	GLY499

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL C 811

Chain	Residue
C	ASN485
C	ASP486
C	GLY511
C	HOH1093

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL C 812

Chain	Residue
C	LEU580
C	ASP581
C	ARG651
C	GLY653
C	ASP654
C	HOH1181

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL C 813

Chain	Residue
C	PRO459
C	ALA461
C	HOH1123
C	HOH1131

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL C 814

Chain	Residue
C	ARG591
C	GLU640
C	ILE646
C	ARG684

---

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 815

Chain	Residue
A	GLN177
C	GLY442
C	LEU443
C	PRO444
C	HOH1059

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 201

Chain	Residue
A	GLN177
C	TRP402
A	GLU172
A	GLY173

---

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 202

Chain	Residue
A	LYS48
A	GLU93
A	LEU94
A	ASP95
A	ASP180

---

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 203

Chain	Residue
A	GLN113
A	TRP116
A	THR159
A	ASP160
A	HOH321
C	LYS643

---

site_id	CC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 204

Chain	Residue
A	PHE137
A	ALA141
A	ASP142
A	GLY143
A	LYS144
A	THR145
A	THR146
A	HOH405

---

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 205

Chain	Residue
A	TRP105
A	LEU106
A	ARG167
A	HOH427
C	GOL804

---

site_id	CC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 206

Chain	Residue
A	ALA70
A	VAL74
A	ARG77
A	GLU79
A	TYR83
A	TRP153
A	ARG155
A	HOH344
A	HOH354
A	HOH411

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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