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PDB: 53878 results

4LT7
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BU of 4lt7 by Molmil
Crystal structure of the c2a domain of rabphilin-3a in complex with a calcium
Descriptor: CALCIUM ION, Rabphilin-3A
Authors:Verdaguer, N, Ferrer-Orta, C, Buxaderas, M, Corbalan-Garcia, S, Perez-Sanchez, D, Guerrero-Valero, M, Luengo, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Guillen, J.
Deposit date:2013-07-23
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
1U3Y
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BU of 1u3y by Molmil
Crystal structure of ILAC mutant of dimerisation domain of NF-kB p50 transcription factor
Descriptor: Nuclear factor NF-kappa-B p105 subunit
Authors:Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M.
Deposit date:2004-07-22
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
1U42
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BU of 1u42 by Molmil
Crystal structure of MLAM mutant of dimerisation domain of NF-kB p50 transcription factor
Descriptor: Nuclear factor NF-kappa-B p105 subunit
Authors:Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M.
Deposit date:2004-07-23
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.699 Å)
Cite:Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
1CRH
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BU of 1crh by Molmil
THE ROLE OF A CONSERVED INTERNAL WATER MOLECULE AND ITS ASSOCIATED HYDROGEN BOND NETWORK IN CYTOCHROME C
Descriptor: CYTOCHROME C, HEME C, SULFATE ION
Authors:Berghuis, A.M, Brayer, G.D.
Deposit date:1993-08-06
Release date:1994-01-31
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The role of a conserved internal water molecule and its associated hydrogen bond network in cytochrome c.
J.Mol.Biol., 236, 1994
8WJO
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BU of 8wjo by Molmil
Cryo-EM structure of 8-subunit Smc5/6 arm region
Descriptor: DNA repair protein KRE29, E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, ...
Authors:Li, Q, Zhang, J, Zhang, X, Cheng, T, Wang, Z, Jin, D, Chen, Z, Wang, L.
Deposit date:2023-09-26
Release date:2024-06-26
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (6.04 Å)
Cite:Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 31, 2024
1D1J
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BU of 1d1j by Molmil
CRYSTAL STRUCTURE OF HUMAN PROFILIN II
Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, PROFILIN II, ...
Authors:Nodelman, I.M, Bowman, G.D, Lindberg, U, Schutt, C.E.
Deposit date:1999-09-17
Release date:2000-12-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray structure determination of human profilin II: A comparative structural analysis of human profilins.
J.Mol.Biol., 294, 1999
3EN3
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BU of 3en3 by Molmil
Crystal Structure of the GluR4 Ligand-Binding domain in complex with kainate
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 4,Glutamate receptor
Authors:Gill, A, Madden, D.R.
Deposit date:2008-09-25
Release date:2009-05-19
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Correlating AMPA receptor activation and cleft closure across subunits: crystal structures of the GluR4 ligand-binding domain in complex with full and partial agonists
Biochemistry, 47, 2008
5ZUR
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BU of 5zur by Molmil
Achromobacter Dh1f Bacterioferritin
Descriptor: BARIUM ION, Bacterioferritin, CHLORIDE ION, ...
Authors:Dwivedy, A, Jha, B, Singh, K.H, Ahmed, M, Ashraf, A, Kumar, D, Biswal, B.K.
Deposit date:2018-05-08
Release date:2018-09-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Serendipitous crystallization and structure determination of bacterioferritin from Achromobacter.
Acta Crystallogr F Struct Biol Commun, 74, 2018
8PJN
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BU of 8pjn by Molmil
Catalytic module of human CTLH E3 ligase bound to multiphosphorylated UBE2H~ubiquitin
Descriptor: E3 ubiquitin-protein transferase MAEA, E3 ubiquitin-protein transferase RMND5A, Ubiquitin, ...
Authors:Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A.
Deposit date:2023-06-23
Release date:2024-01-03
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.
Mol.Cell, 84, 2024
8PMQ
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BU of 8pmq by Molmil
Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin
Descriptor: E3 ubiquitin-protein ligase RMD5, Protein FYV10, Ubiquitin, ...
Authors:Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A.
Deposit date:2023-06-29
Release date:2024-01-03
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.
Mol.Cell, 84, 2024
7TXL
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BU of 7txl by Molmil
Crystal structure of EgtU solute binding domain from Streptococcus pneumoniae D39 in complex with L-ergothioneine
Descriptor: 1,2-ETHANEDIOL, Choline transporter (Glycine betaine transport system permease protein), trimethyl-[(2S)-1-oxidanyl-1-oxidanylidene-3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)propan-2-yl]azanium
Authors:Zhang, Y, Gonzalez-Gutierrez, G, Giedroc, D.P.
Deposit date:2022-02-09
Release date:2022-12-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Discovery and structure of a widespread bacterial ABC transporter specific for ergothioneine.
Nat Commun, 13, 2022
7TXK
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BU of 7txk by Molmil
Crystal structure of EgtU solute binding domain from Streptococcus pneumoniae D39 in complex with L-ergothioneine
Descriptor: 1,2-ETHANEDIOL, Choline transporter (Glycine betaine transport system permease protein), SULFATE ION, ...
Authors:Zhang, Y, Gonzalez-Gutierrez, G, Giedroc, D.P.
Deposit date:2022-02-09
Release date:2022-12-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Discovery and structure of a widespread bacterial ABC transporter specific for ergothioneine.
Nat Commun, 13, 2022
1D7H
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BU of 1d7h by Molmil
FKBP COMPLEXED WITH DMSO
Descriptor: AMMONIUM ION, DIMETHYL SULFOXIDE, PROTEIN (FK506-BINDING PROTEIN), ...
Authors:Burkhard, P, Taylor, P, Walkinshaw, M.D.
Deposit date:1999-10-18
Release date:1999-10-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
3IXY
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BU of 3ixy by Molmil
The pseudo-atomic structure of dengue immature virus in complex with Fab fragments of the anti-fusion loop antibody E53
Descriptor: E53 Fab Fragment (chain H), E53 Fab Fragment (chain L), Envelope protein E, ...
Authors:Cherrier, M.V, Kaufmann, B, Nybakken, G.E, Lok, S.M, Warren, J.T, Nelson, C.A, Kostyuchenko, V.A, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Diamond, M.S, Rossmann, M.G, Fremont, D.H.
Deposit date:2009-02-26
Release date:2009-10-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody
Embo J., 28, 2009
4D2S
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BU of 4d2s by Molmil
Human TTK in complex with a Dyrk1B inhibitor
Descriptor: DUAL SPECIFICITY PROTEIN KINASE TTK, N-{2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]phenyl}-4-(1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine
Authors:Debreczeni, J.E, Kettle, J.G, Ballard, P, Bardelle, C, Butterworth, S, Colclough, N, Critchlow, S.E, Fairley, G, Fillery, S, Graham, M.A, Goodwin, L, Guichard, S, Hudson, K, Mahmood, A, Vincent, J, Ward, R.A, Whittaker, D.
Deposit date:2014-05-12
Release date:2015-04-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery and Optimization of a Novel Series of Dyrk1B Kinase Inhibitors to Explore a Mek Resistance Hypothesis.
J.Med.Chem., 58, 2015
8FH5
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BU of 8fh5 by Molmil
Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-001
Descriptor: (8-oxo-7-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-7,8-dihydropyrazino[2,3-d]pyridazin-5-yl)acetic acid, Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Arenas, R, Wilson, D.K.
Deposit date:2022-12-13
Release date:2023-12-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-001
To Be Published
5F02
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BU of 5f02 by Molmil
CATHEPSIN L IN COMPLEX WITH (2S,4R)-4-(2-Chloro-4-methoxy-benzenesulfonyl)-1-[3-(5-chloro-pyridin-2-yl)-azetidine-3-carbonyl]-pyrrolidine-2-carboxylic acid (1-cyano-cyclopropyl)-amide
Descriptor: (2~{S},4~{R})-4-[(2-chloranyl-4-methoxy-phenyl)-bis(oxidanyl)-$l^{4}-sulfanyl]-1-[3-(5-chloranylpyridin-2-yl)azetidin-3-yl]carbonyl-~{N}-[1-(iminomethyl)cyclopropyl]pyrrolidine-2-carboxamide, Cathepsin L1, GLYCEROL
Authors:Banner, D, Benz, J, Stihle, M, Kuglstatter, A.
Deposit date:2015-11-27
Release date:2016-02-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:A Real-World Perspective on Molecular Design.
J.Med.Chem., 59, 2016
8FH9
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BU of 8fh9 by Molmil
Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-007
Descriptor: (4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-3,4-dihydrothieno[3,4-d]pyridazin-1-yl)acetic acid, 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member B1, ...
Authors:Arenas, R, Wilson, D.K.
Deposit date:2022-12-13
Release date:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-007
To Be Published
7M1M
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BU of 7m1m by Molmil
Crystal structure of Pseudomonas aeruginosa ClpP1
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit
Authors:Mawla, G.D, Grant, R.A, Baker, T.A, Sauer, R.T.
Deposit date:2021-03-13
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:ClpP1P2 peptidase activity promotes biofilm formation in Pseudomonas aeruginosa.
Mol.Microbiol., 115, 2021
8A12
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BU of 8a12 by Molmil
Plasmodium falciparum Myosin A full-length, post-rigor state complexed to Mg.ATP-gamma-S
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Moussaoui, D, Robblee, J.P, Auguin, D, Fisher, F, Fagnant, P.M, MacFarlane, J.E, Mueller-Dieckmann, C, Baum, J, Robert-Paganin, J, Trybus, K.M, Houdusse, A.
Deposit date:2022-05-31
Release date:2023-06-21
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Mechanism of small molecule inhibition of Plasmodium falciparum myosin A informs antimalarial drug design.
Nat Commun, 14, 2023
8FH6
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BU of 8fh6 by Molmil
Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And Two AT-001
Descriptor: (8-oxo-7-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-7,8-dihydropyrazino[2,3-d]pyridazin-5-yl)acetic acid, 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member B1, ...
Authors:Arenas, R, Wilson, D.K.
Deposit date:2022-12-13
Release date:2023-12-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And Two AT-001
To Be Published
8FH7
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BU of 8fh7 by Molmil
Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-003
Descriptor: 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Arenas, R, Wilson, D.K.
Deposit date:2022-12-13
Release date:2023-12-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-003
To Be Published
6R8I
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BU of 6r8i by Molmil
PP4R3A EVH1 domain bound to FxxP motif
Descriptor: SER-LEU-PRO-PHE-THR-PHE-LYS-VAL-PRO-ALA-PRO-PRO-PRO-SER-LEU-PRO-PRO-SER, Serine/threonine-protein phosphatase 4 regulatory subunit 3A
Authors:Ueki, Y, Kruse, T, Weisser, M.B, Sundell, G.N, Yoo Larsen, M.S, Lopez Mendez, B, Jenkins, N.P, Garvanska, D.H, Cressey, L, Zhang, G, Davey, N, Montoya, G, Ivarsson, Y, Kettenbach, A, Nilsson, J.
Deposit date:2019-04-02
Release date:2019-10-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.517 Å)
Cite:A Consensus Binding Motif for the PP4 Protein Phosphatase.
Mol.Cell, 76, 2019
5EZX
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BU of 5ezx by Molmil
CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH {(1R,2R)-2-[(R)-2-Amino-4-(4-difluoromethoxy-phenyl)-4,5-dihydro-oxazol-4-yl]-cyclopropyl}-(5-chloro-pyridin-3-yl)-methanone
Descriptor: Beta-secretase 1, DIMETHYL SULFOXIDE, SODIUM ION, ...
Authors:Banner, D, Benz, J, Stihle, M, Kuglstatter, A.
Deposit date:2015-11-27
Release date:2016-02-24
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Real-World Perspective on Molecular Design.
J.Med.Chem., 59, 2016
7OOF
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BU of 7oof by Molmil
Crystal structure of Paradendryphiella salina PL7A alginate lyase in complex with tri-mannuronic acid
Descriptor: Alginate lyase (PL7), TETRAETHYLENE GLYCOL, alpha-D-mannopyranuronic acid, ...
Authors:Fredslund, F, Welner, D.H, Wilkens, C.
Deposit date:2021-05-27
Release date:2022-06-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of Paradendryphiella salina PL7A alginate lyase in complex with tri-mannuronic acid
To Be Published

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