8FH9

Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-007

Summary for 8FH9

• Entry DOI: 10.2210/pdb8fh9/pdb
• Descriptor: Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-3,4-dihydrothieno[3,4-d]pyridazin-1-yl)acetic acid, ... (5 entities in total)
• Functional Keywords: complex, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37377.49

Authors

Arenas, R.,Wilson, D.K. (deposition date: 2022-12-13, release date: 2023-12-20)

• Primary citation: Arenas, R.,Wilson, D.K.; Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And AT-007; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)