4LT7

Crystal structure of the c2a domain of rabphilin-3a in complex with a calcium

Summary for 4LT7

Related2CHD 2K3H 2CM5 2CM6
DescriptorRabphilin-3A, CALCIUM ION (3 entities in total)
Functional Keywordscalcium binding, c2 domain, signal transduction, protein transport
Biological sourceRattus norvegicus (brown rat,rat,rats)
Cellular locationCell junction, synapse  P47709
Total number of polymer chains1
Total molecular weight15345.56
Authors
Primary citation
Guillen, J.,Ferrer-Orta, C.,Buxaderas, M.,Perez-Sanchez, D.,Guerrero-Valero, M.,Luengo-Gil, G.,Pous, J.,Guerra, P.,Gomez-Fernandez, J.C.,Verdaguer, N.,Corbalan-Garcia, S.
Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc.Natl.Acad.Sci.USA, 110:20503-20508, 2013
PubMed: 24302762 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1316179110
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.28630.8%2.7%0.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report