Crystal structure of ILAC mutant of dimerisation domain of NF-kB p50 transcription factor

Summary for 1U3Y

Related1U36 1U3J 1U3Z 1U41 1U42
DescriptorNuclear factor NF-kappa-B p105 subunit (2 entities in total)
Functional Keywordstranscription factor; nf-kb; dimerization domain; intertwined folding, transcription
Biological sourceMus musculus (house mouse)
Cellular locationNucleus. Isoform 5: Cytoplasm. Isoform 6: Nucleus. Isoform 7: Nucleus P25799
Total number of polymer chains1
Total molecular weight12210.83
Chirgadze, D.Y.,Demydchuk, M.,Becker, M.,Moran, S.,Paoli, M. (deposition date: 2004-07-22, release date: 2004-08-17, Last modification date: 2017-02-01)
Primary citation
Chirgadze, D.Y.,Demydchuk, M.,Becker, M.,Moran, S.,Paoli, M.
Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12:1489-1494, 2004
PubMed: 15296742 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2004.06.011
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24360 1.1% 1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25