4KC9
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![BU of 4kc9 by Molmil](/molmil-images/mine/4kc9) | Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism | 分子名称: | E3 ubiquitin-protein ligase ARIH1, ZINC ION | 著者 | Duda, D.M, Olszewski, J.L, Schulman, B.A. | 登録日 | 2013-04-24 | 公開日 | 2013-05-29 | 最終更新日 | 2013-07-03 | 実験手法 | X-RAY DIFFRACTION (3.603 Å) | 主引用文献 | Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism. Structure, 21, 2013
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1YOV
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3T7G
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![BU of 3t7g by Molmil](/molmil-images/mine/3t7g) | Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway | 分子名称: | Autophagy-related protein 3, Ubiquitin-like modifier-activating enzyme ATG7 | 著者 | Taherbhoy, A.M, Tait, S.W, Kaiser, S.E, Williams, A.H, Deng, A, Nourse, A, Hammel, M, Kurinov, I, Rock, C.O, Green, D.R, Schulman, B.A. | 登録日 | 2011-07-30 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and mechanism in the autophagy pathway. Mol.Cell, 44, 2011
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3DQV
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![BU of 3dqv by Molmil](/molmil-images/mine/3dqv) | Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation | 分子名称: | Cullin-5, NEDD8, Rbx1, ... | 著者 | Duda, D.M, Borg, L.A, Scott, D.C, Hunt, H.W, Hammel, M, Schulman, B.A. | 登録日 | 2008-07-09 | 公開日 | 2008-09-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation. Cell(Cambridge,Mass.), 134, 2008
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1R4N
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![BU of 1r4n by Molmil](/molmil-images/mine/1r4n) | APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Ubiquitin-like protein NEDD8, ZINC ION, ... | 著者 | Walden, H, Podgorski, M.S, Holton, J.M, Schulman, B.A. | 登録日 | 2003-10-07 | 公開日 | 2003-12-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1. Mol.Cell, 12, 2003
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3GA4
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![BU of 3ga4 by Molmil](/molmil-images/mine/3ga4) | Crystal structure of Ost6L (photoreduced form) | 分子名称: | 1,2-ETHANEDIOL, Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST6, TETRAETHYLENE GLYCOL | 著者 | Stirnimann, C.U, Grimshaw, J.P.A, Schulz, B.L, Brozzo, M.S, Fritsch, F, Glockshuber, R, Capitani, G, Gruetter, M.G, Aebi, M. | 登録日 | 2009-02-16 | 公開日 | 2009-06-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency. Proc.Natl.Acad.Sci.USA, 106, 2009
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3O2P
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![BU of 3o2p by Molmil](/molmil-images/mine/3o2p) | A Dual E3 Mechanism for Rub1 Ligation to Cdc53: Dcn1(P)-Cdc53(WHB) | 分子名称: | Cell division control protein 53, Defective in cullin neddylation protein 1, GLYCEROL | 著者 | Scott, D.C, Monda, J.K, Grace, C.R.R, Duda, D.M, Kriwacki, R.W, Kurz, T, Schulman, B.A. | 登録日 | 2010-07-22 | 公開日 | 2010-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.233 Å) | 主引用文献 | A dual E3 mechanism for Rub1 ligation to Cdc53. Mol.Cell, 39, 2010
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3G9B
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![BU of 3g9b by Molmil](/molmil-images/mine/3g9b) | Crystal structure of reduced Ost6L | 分子名称: | Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST6 | 著者 | Stirnimann, C.U, Grimshaw, J.P.A, Schulz, B.L, Brozzo, M.S, Fritsch, F, Glockshuber, R, Capitani, G, Gruetter, M.G, Aebi, M. | 登録日 | 2009-02-13 | 公開日 | 2009-06-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency. Proc.Natl.Acad.Sci.USA, 106, 2009
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3TDZ
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![BU of 3tdz by Molmil](/molmil-images/mine/3tdz) | N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex: Structure of a human Cul1WHB-Dcn1P-stapled acetylated Ubc12N complex | 分子名称: | Cullin-1, DCN1-like protein 1, STAPLED PEPTIDE | 著者 | Scott, D.C, Monda, J.K, Bennett, E.J, Harper, J.W, Schulman, B.A. | 登録日 | 2011-08-11 | 公開日 | 2011-10-12 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex. Science, 334, 2011
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3ONG
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![BU of 3ong by Molmil](/molmil-images/mine/3ong) | Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways | 分子名称: | SUMO-conjugating enzyme UBC9, Ubiquitin-activating enzyme E1-like | 著者 | Wang, J, Taherbhoy, A.M, Hunt, H.W, Seyedin, S.N, Miller, D.W, Huang, D.T, Schulman, B.A. | 登録日 | 2010-08-28 | 公開日 | 2011-01-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways. Plos One, 5, 2010
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1R4M
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![BU of 1r4m by Molmil](/molmil-images/mine/1r4m) | APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex | 分子名称: | Ubiquitin-like protein NEDD8, ZINC ION, amyloid beta precursor protein-binding protein 1, ... | 著者 | Walden, H, Podgorski, M.S, Holton, J.M, Schulman, B.A. | 登録日 | 2003-10-07 | 公開日 | 2003-12-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1. Mol.Cell, 12, 2003
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4FR3
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![BU of 4fr3 by Molmil](/molmil-images/mine/4fr3) | Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilizer 16-O-Me-FC-H | 分子名称: | (4R,5R,6R,6aS,9S,9aE,10aR)-5-hydroxy-9-(methoxymethyl)-6,10a-dimethyl-3-(propan-2-yl)-1,2,4,5,6,6a,7,8,9,10a-decahydrodicyclopenta[a,d][8]annulen-4-yl alpha-D-glucopyranoside, 14-3-3 protein sigma, MAGNESIUM ION, ... | 著者 | Ottmann, C, Anders, C, Schumacher, B. | 登録日 | 2012-06-26 | 公開日 | 2013-05-08 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of k(+) channels at the cell surface. Chem.Biol., 20, 2013
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3G7Y
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![BU of 3g7y by Molmil](/molmil-images/mine/3g7y) | Crystal structure of oxidized Ost6L | 分子名称: | Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST6 | 著者 | Stirnimann, C.U, Grimshaw, J.P.A, Schulz, B.L, Brozzo, M.S, Fritsch, F, Glockshuber, R, Capitani, G, Gruetter, M.G, Aebi, M. | 登録日 | 2009-02-11 | 公開日 | 2009-06-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.215 Å) | 主引用文献 | Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency. Proc.Natl.Acad.Sci.USA, 106, 2009
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3TDU
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![BU of 3tdu by Molmil](/molmil-images/mine/3tdu) | N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex: Structure of a human Cul1WHB-Dcn1P-acetylated Ubc12N complex | 分子名称: | Cullin-1, DCN1-like protein 1, NEDD8-conjugating enzyme Ubc12 | 著者 | Scott, D.C, Monda, J.K, Bennett, E.J, Harper, J.W, Schulman, B.A. | 登録日 | 2011-08-11 | 公開日 | 2011-10-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex. Science, 334, 2011
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4GSJ
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![BU of 4gsj by Molmil](/molmil-images/mine/4gsj) | Crystal structure of Atg7 NTD K14A F16A D18A mutant | 分子名称: | CITRIC ACID, ISOPROPYL ALCOHOL, Ubiquitin-like modifier-activating enzyme ATG7 | 著者 | Kaiser, S.E, Mao, K, Taherbhoy, A.M, Yu, S, Olszewski, J.L, Duda, D.M, Kurinov, I, Deng, A, Fenn, T.D, Klionsky, D.J, Schulman, B.A. | 登録日 | 2012-08-27 | 公開日 | 2012-11-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.695 Å) | 主引用文献 | Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures. Nat.Struct.Mol.Biol., 19, 2012
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2GJD
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![BU of 2gjd by Molmil](/molmil-images/mine/2gjd) | Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress | 分子名称: | Ubiquitin-conjugating enzyme E2-18 kDa | 著者 | van Waardenburg, R.C, Duda, D.M, Lancaster, C.S, Schulman, B.A, Bjornsti, M.A. | 登録日 | 2006-03-30 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Distinct functional domains of ubc9 dictate cell survival and resistance to genotoxic stress. Mol.Cell.Biol., 26, 2006
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1P22
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![BU of 1p22 by Molmil](/molmil-images/mine/1p22) | Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity on the SCFbeta-TrCP1 ubiquitin ligase | 分子名称: | Beta-catenin, F-box/WD-repeat protein 1A, Skp1 | 著者 | Wu, G, Xu, G, Schulman, B.A, Jeffrey, P.D, Harper, J.W, Pavletich, N.P. | 登録日 | 2003-04-14 | 公開日 | 2003-07-08 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structure of a beta-TrCP1-Skp1-beta-Catenin complex: destruction motif binding and lysine specificity of the SCFbeta-TrCP1 ubiquitin ligase Mol.Cell, 11, 2003
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3DPL
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3SP5
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![BU of 3sp5 by Molmil](/molmil-images/mine/3sp5) | Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Cotylenol | 分子名称: | 14-3-3 protein sigma, Cotylenol, MAGNESIUM ION, ... | 著者 | Anders, C, Schumacher, B, Ottmann, C. | 登録日 | 2011-07-01 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem.Biol., 20, 2013
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3T7F
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![BU of 3t7f by Molmil](/molmil-images/mine/3t7f) | Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway | 分子名称: | Ubiquitin-like modifier-activating enzyme ATG7 | 著者 | Taherbhoy, A.M, Tait, S.W, Kaiser, S.E, Williams, A.H, Deng, A, Nourse, A, Hammel, M, Kurinov, I, Rock, C.O, Green, D.R, Schulman, B.A. | 登録日 | 2011-07-30 | 公開日 | 2011-11-23 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Atg8 transfer from atg7 to atg3: a distinctive e1-e2 architecture and mechanism in the autophagy pathway. Mol.Cell, 44, 2011
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3SMM
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![BU of 3smm by Molmil](/molmil-images/mine/3smm) | Crystal structure of human 14-3-3 sigma C38N/N166H in complex with task-3 peptide and stabilizer Fusicoccin J aglycone | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, Fusicoccin J aglycone, ... | 著者 | Anders, C, Schumacher, B, Ottmann, C. | 登録日 | 2011-06-28 | 公開日 | 2012-07-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
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3P1P
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![BU of 3p1p by Molmil](/molmil-images/mine/3p1p) | Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide | 分子名称: | 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CHLORIDE ION, ... | 著者 | Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C. | 登録日 | 2010-09-30 | 公開日 | 2011-10-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface Chem. Biol., 20, 2013
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3SML
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![BU of 3sml by Molmil](/molmil-images/mine/3sml) | Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide and stabilizer Fusicoccin A aglycone | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, Fusicoccin A aglycone, ... | 著者 | Anders, C, Schumacher, B, Ottmann, C. | 登録日 | 2011-06-28 | 公開日 | 2012-07-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
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3P1Q
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![BU of 3p1q by Molmil](/molmil-images/mine/3p1q) | Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 Peptide and stabilizer fusicoccin A | 分子名称: | 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CALCIUM ION, ... | 著者 | Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C. | 登録日 | 2010-09-30 | 公開日 | 2011-10-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface Chem. Biol., 20, 2013
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3SMK
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![BU of 3smk by Molmil](/molmil-images/mine/3smk) | Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Cotylenin A | 分子名称: | 14-3-3 protein sigma, Cotylenin A, MAGNESIUM ION, ... | 著者 | Anders, C, Schumacher, B, Ottmann, C. | 登録日 | 2011-06-28 | 公開日 | 2012-07-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
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