Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation.

Summary for 3DPL

DescriptorCullin-5, RING-box protein 1, ZINC ION, ... (4 entities in total)
Functional Keywordsubiquitin, nedd8, cullin, host-virus interaction, receptor, ubl conjugation, ubl conjugation pathway, acetylation, cytoplasm, dna damage, dna repair, metal-binding, nucleus, zinc, zinc-finger, ligase
Biological sourceHomo sapiens
Cellular locationCytoplasm P62877
Total number of polymer chains2
Total molecular weight57278.1
Duda, D.M.,Schulman, B.A. (deposition date: 2008-07-08, release date: 2008-09-30, Last modification date: 2011-07-13)
Primary citation
Duda, D.M.,Borg, L.A.,Scott, D.C.,Hunt, H.W.,Hammel, M.,Schulman, B.A.
Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.
Cell(Cambridge,Mass.), 134:995-1006, 2008
PubMed: 18805092 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2008.07.022
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24925 3.3% 5.9% 3.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25