3EK6
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1EOD
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![BU of 1eod by Molmil](/molmil-images/mine/1eod) | CRYSTAL STRUCTURE OF THE N136D MUTANT OF A SHAKER T1 DOMAIN | 分子名称: | POTASSIUM CHANNEL KV1.1 | 著者 | Nanao, M.H, Cushman, S.J, Jahng, A.W, DeRubeis, D, Choe, S, Pfaffinger, P.J. | 登録日 | 2000-03-22 | 公開日 | 2000-05-02 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Voltage dependent activation of potassium channels is coupled to T1 domain structure. Nat.Struct.Biol., 7, 2000
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2ZE3
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1EOF
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![BU of 1eof by Molmil](/molmil-images/mine/1eof) | CRYSTAL STRUCTURE OF THE N136A MUTANT OF A SHAKER T1 DOMAIN | 分子名称: | POTASSIUM CHANNEL KV1.1 | 著者 | Nanao, M.H, Cushman, S.J, Jahng, A.W, DeRubeis, D, Choe, S, Pfaffinger, P.J. | 登録日 | 2000-03-22 | 公開日 | 2000-05-02 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Voltage dependent activation of potassium channels is coupled to T1 domain structure. Nat.Struct.Biol., 7, 2000
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1OMT
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![BU of 1omt by Molmil](/molmil-images/mine/1omt) | SOLUTION STRUCTURE OF OVOMUCOID (THIRD DOMAIN) FROM DOMESTIC TURKEY (298K, PH 4.1) (NMR, 50 STRUCTURES) (STANDARD NOESY ANALYSIS) | 分子名称: | OVOMUCOID (THIRD DOMAIN) | 著者 | Hoogstraten, C.G, Choe, S, Westler, W.M, Markley, J.L. | 登録日 | 1995-10-11 | 公開日 | 1996-03-08 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Comparison of the accuracy of protein solution structures derived from conventional and network-edited NOESY data. Protein Sci., 4, 1995
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2MBF
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1H1V
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![BU of 1h1v by Molmil](/molmil-images/mine/1h1v) | gelsolin G4-G6/actin complex | 分子名称: | ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | 著者 | Choe, H, Burtnick, L.D, Mejillano, M, Yin, H.L, Robinson, R.C, Choe, S. | 登録日 | 2002-07-23 | 公開日 | 2003-01-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | The Calcium Activation of Gelsolin:Insights from the 3A Structure of the G4-G6/Actin Complex J.Mol.Biol., 324, 2002
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4BGG
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![BU of 4bgg by Molmil](/molmil-images/mine/4bgg) | Crystal structure of the ACVR1 kinase in complex with LDN-213844 | 分子名称: | 1,2-ETHANEDIOL, 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine, ACTIVIN RECEPTOR TYPE-1, ... | 著者 | Sanvitale, C, Canning, P, Cooper, C, Wang, Y, Mohedas, A.H, Choi, S, Yu, P.B, Cuny, G.D, Nowak, R, Coutandin, D, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | 登録日 | 2013-03-26 | 公開日 | 2013-04-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Structure-Activity Relationship of 3,5-Diaryl-2-Aminopyridine Alk2 Inhibitors Reveals Unaltered Binding Affinity for Fibrodysplasia Ossificans Progressiva Causing Mutants. J.Med.Chem., 57, 2014
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3JSU
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![BU of 3jsu by Molmil](/molmil-images/mine/3jsu) | Quadruple mutant(N51I+C59R+S108N+I164L) plasmodium falciparum dihydrofolate reductase-thymidylate synthase(PFDHFR-TS) complexed with QN254, NADPH, and dUMP | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-chloro-N~6~-(2,5-dimethoxybenzyl)quinazoline-2,4,6-triamine, Dihydrofolate reductase-thymidylate synthase, ... | 著者 | Chitnumsub, P, Maneeruttanarungroj, C, Kamchonwongpaisan, S, Yuthavong, Y, Diagana, T.T. | 登録日 | 2009-09-11 | 公開日 | 2010-07-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Preclinical evaluation of the antifolate QN254, 5-chloro- N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug candidate Antimicrob.Agents Chemother., 54, 2010
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4P3X
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![BU of 4p3x by Molmil](/molmil-images/mine/4p3x) | Structure of the Fe4S4 quinolinate synthase NadA from Thermotoga maritima | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, IRON/SULFUR CLUSTER, Quinolinate synthase A, ... | 著者 | Cherrier, M.V, Chan, A, Darnault, C, Reichmann, D, Amara, P, Ollagnier de Choudens, S, Fontecilla-Camps, J.C. | 登録日 | 2014-03-10 | 公開日 | 2014-04-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The crystal structure of Fe4S4 quinolinate synthase unravels an enzymatic dehydration mechanism that uses tyrosine and a hydrolase-type triad. J.Am.Chem.Soc., 136, 2014
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2E12
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![BU of 2e12 by Molmil](/molmil-images/mine/2e12) | The crystal structure of XC5848 from Xanthomonas campestris adopting a novel variant of Sm-like motif | 分子名称: | Hypothetical protein XCC3642 | 著者 | Chin, K.-H, Ruan, S.-K, Wang, A.H.-J, Chou, S.-H. | 登録日 | 2006-10-17 | 公開日 | 2007-10-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | XC5848, an ORFan protein from Xanthomonas campestris, adopts a novel variant of Sm-like motif Proteins, 68, 2007
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1T2F
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![BU of 1t2f by Molmil](/molmil-images/mine/1t2f) | Human B lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid | 分子名称: | 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID, L-lactate dehydrogenase B chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | 登録日 | 2004-04-21 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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1T2D
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![BU of 1t2d by Molmil](/molmil-images/mine/1t2d) | Plasmodium falciparum lactate dehydrogenase complexed with NAD+ and oxalate | 分子名称: | GLYCEROL, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | 登録日 | 2004-04-21 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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1XQC
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![BU of 1xqc by Molmil](/molmil-images/mine/1xqc) | X-ray structure of ERalpha LBD bound to a tetrahydroisoquinoline SERM ligand at 2.05A resolution | 分子名称: | (1S)-1-{4-[(9AR)-OCTAHYDRO-2H-PYRIDO[1,2-A]PYRAZIN-2-YL]PHENYL}-2-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLIN-6-OL, Estrogen receptor | 著者 | Renaud, J, Bischoff, S.F, Buhl, T, Floersheim, P, Fournier, B, Geiser, M, Halleux, C, Kallen, J, Keller, H.J, Ramage, P. | 登録日 | 2004-10-12 | 公開日 | 2005-02-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Selective Estrogen Receptor Modulators with Conformationally Restricted Side Chains. Synthesis and Structure-Activity Relationship of ERalpha-Selective Tetrahydroisoquinoline Ligands J.Med.Chem., 48, 2005
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3OYY
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1NN7
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2AQA
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1T2C
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![BU of 1t2c by Molmil](/molmil-images/mine/1t2c) | Plasmodium falciparum lactate dehydrogenase complexed with NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, L-lactate dehydrogenase | 著者 | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | 登録日 | 2004-04-21 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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1T25
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![BU of 1t25 by Molmil](/molmil-images/mine/1t25) | Plasmodium falciparum lactate dehydrogenase complexed with NADH and 3-hydroxyisoxazole-4-carboxylic acid | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-HYDROXYISOXAZOLE-4-CARBOXYLIC ACID, GLYCEROL, ... | 著者 | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | 登録日 | 2004-04-20 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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3H8C
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![BU of 3h8c by Molmil](/molmil-images/mine/3h8c) | A combined crystallographic and molecular dynamics study of cathepsin-L retro-binding inhibitors (compound 14) | 分子名称: | Cathepsin L1, N-(biphenyl-4-ylacetyl)-S-methyl-L-cysteinyl-D-arginyl-N-(2-phenylethyl)-L-phenylalaninamide | 著者 | Tulsidas, S.R, Chowdhury, S.F, Kumar, S, Joseph, L, Purisima, E.O, Sivaraman, J. | 登録日 | 2009-04-29 | 公開日 | 2009-10-20 | 最終更新日 | 2014-11-12 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A Combined Crystallographic and Molecular Dynamics Study of Cathepsin L Retrobinding Inhibitors J.Med.Chem., 2009
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1T26
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![BU of 1t26 by Molmil](/molmil-images/mine/1t26) | Plasmodium falciparum lactate dehydrogenase complexed with NADH and 4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-HYDROXY-1,2,5-THIADIAZOLE-3-CARBOXYLIC ACID, L-lactate dehydrogenase | 著者 | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | 登録日 | 2004-04-20 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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2KM4
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![BU of 2km4 by Molmil](/molmil-images/mine/2km4) | Solution structure of Rtt103 CTD interacting domain | 分子名称: | Regulator of Ty1 transposition protein 103 | 著者 | Lunde, B.M, Reichow, S, Kim, M, Leeper, T.C, Becker, R, Buratowski, S, Meinhart, A, Varani, G. | 登録日 | 2009-07-20 | 公開日 | 2010-09-08 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain. Nat.Struct.Mol.Biol., 17, 2010
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1T24
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![BU of 1t24 by Molmil](/molmil-images/mine/1t24) | Plasmodium falciparum lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid | 分子名称: | 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID, GLYCEROL, L-lactate dehydrogenase, ... | 著者 | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | 登録日 | 2004-04-20 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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1T2E
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![BU of 1t2e by Molmil](/molmil-images/mine/1t2e) | Plasmodium falciparum lactate dehydrogenase S245A, A327P mutant complexed with NADH and oxamate | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, L-lactate dehydrogenase, ... | 著者 | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | 登録日 | 2004-04-21 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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3V3W
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![BU of 3v3w by Molmil](/molmil-images/mine/3v3w) | Crystal structure of an enolase from the soil bacterium Cellvibrio japonicus (TARGET EFI-502161) with bound MG and glycerol | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, GLYCEROL, ... | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Sojitra, S, Seidel, R, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2011-12-14 | 公開日 | 2012-01-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of an enolase from the soil bacterium Cellvibrio japonicus (TARGET EFI-502161) with bound MG and glycerol to be published
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