1T2C

Plasmodium falciparum lactate dehydrogenase complexed with NADH

Summary for 1T2C
Related1LDG 1T24 1T25 1T26 1T2E 1T2F
DescriptorL-lactate dehydrogenase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, ... (4 entities in total)
Functional Keywordsbinary complex, oxidoreductase
Biological sourcePlasmodium falciparum (malaria parasite P. falciparum)
Total number of polymer chains1
Total formula weight35735.12
Authors
Primary citationBarros, D.,Brady, R.L.,Cameron, A.,Croft, S.L.,De Las Heras, F.G.,Easton, A.,Gabarro, R.,Gamo, F.J.,Garcia-Ochoa, S.,Kendrick, H.,Lavandera, J.L.,Leon, L.,Mallo, A.,Martin, J.J.,Read, J.,Risco, F.,Ruiz, J.R.,Sanz, L.,Sessions, R.B.,Tranter, R.,Vivas, L.,Winter, V.J.
Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity.
J.Biol.Chem., 279:31429-31439, 2004
PubMed: 15117937
DOI: 110.1074/jbc.M402433200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.01 Å)
Structure validation
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PDB entries from 2021-06-16