4IK1
 
 | | High resolution structure of GCaMPJ at pH 8.5 | | 分子名称: | CALCIUM ION, RCaMP, Green fluorescent protein | | 著者 | Chen, Y, Song, X, Miao, L, Zhu, Y, Ji, G. | | 登録日 | 2012-12-25 | | 公開日 | 2014-02-05 | | 最終更新日 | 2017-06-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
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4IK4
 | | High resolution structure of GCaMP3 at pH 5.0 | | 分子名称: | CALCIUM ION, RCaMP, Green fluorescent protein | | 著者 | Chen, Y, Song, X, Miao, L, Zhu, Y, Ji, G. | | 登録日 | 2012-12-25 | | 公開日 | 2014-02-05 | | 最終更新日 | 2017-06-21 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
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4IK3
 | | High resolution structure of GCaMP3 at pH 8.5 | | 分子名称: | CALCIUM ION, RCaMP, Green fluorescent protein | | 著者 | Chen, Y, Song, X, Miao, L, Zhu, Y, Ji, G. | | 登録日 | 2012-12-25 | | 公開日 | 2014-01-29 | | 最終更新日 | 2017-06-21 | | 実験手法 | X-RAY DIFFRACTION (2.007 Å) | | 主引用文献 | Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
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4IK9
 | | High resolution structure of GCaMP3 dimer form 2 at pH 7.5 | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, RCaMP, ... | | 著者 | Chen, Y, Song, X, Miao, L, Zhu, Y, Ji, G. | | 登録日 | 2012-12-25 | | 公開日 | 2014-01-29 | | 最終更新日 | 2017-06-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
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4IK8
 | | High resolution structure of GCaMP3 dimer form 1 at pH 7.5 | | 分子名称: | CALCIUM ION, RCaMP, Green fluorescent protein | | 著者 | Chen, Y, Song, X, Miao, L, Zhu, Y, Ji, G. | | 登録日 | 2012-12-25 | | 公開日 | 2014-02-05 | | 最終更新日 | 2017-06-21 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
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1YLP
 | | Atomic resolution structure of CTX-M-27 beta-lactamase | | 分子名称: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase CTX-M-27 | | 著者 | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-19 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability.
J.Mol.Biol., 348, 2005
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1YMS
 | | X-ray crystallographic structure of CTX-M-9 beta-lactamase complexed with nafcinin-like boronic acid inhibitor | | 分子名称: | [(2-ETHOXY-1-NAPHTHOYL)AMINO]METHYLBORONIC ACID, beta-lactamase CTX-M-9 | | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-21 | | 公開日 | 2005-04-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases.
J.Am.Chem.Soc., 127, 2005
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1YLZ
 | | X-ray crystallographic structure of CTX-M-14 beta-lactamase complexed with ceftazidime-like boronic acid | | 分子名称: | BETA-LACTAMASE CTX-M-14, PHOSPHATE ION, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE | | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-19 | | 公開日 | 2005-04-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases.
J.Am.Chem.Soc., 127, 2005
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1YLT
 | | Atomic resolution structure of CTX-M-14 beta-lactamase | | 分子名称: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase CTX-M-14 | | 著者 | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-19 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability.
J.Mol.Biol., 348, 2005
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1YMX
 | | X-ray crystallographic structure of CTX-M-9 beta-lactamase covalently linked to cefoxitin | | 分子名称: | (2R)-5-[(carbamoyloxy)methyl]-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, beta-lactamase CTX-M-9 | | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-21 | | 公開日 | 2005-04-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases.
J.Am.Chem.Soc., 127, 2005
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1YLJ
 | | Atomic resolution structure of CTX-M-9 beta-lactamase | | 分子名称: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase CTX-M-9a | | 著者 | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-19 | | 公開日 | 2005-04-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (0.98 Å) | | 主引用文献 | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability.
J.Mol.Biol., 348, 2005
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1YLY
 | | X-ray crystallographic structure of CTX-M-9 beta-lactamase complexed with ceftazidime-like boronic acid | | 分子名称: | PHOSPHATE ION, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE, beta-lactamase CTX-M-9 | | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-19 | | 公開日 | 2005-04-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases.
J.Am.Chem.Soc., 127, 2005
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1YM1
 | | X-ray crystallographic structure of CTX-M-9 beta-lactamase complexed with a boronic acid inhibitor (SM2) | | 分子名称: | (1R)-1-(2-THIENYLACETYLAMINO)-1-(3-CARBOXYPHENYL)METHYLBORONIC ACID, PHOSPHATE ION, beta-lactamase CTX-M-9a | | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-20 | | 公開日 | 2005-04-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases.
J.Am.Chem.Soc., 127, 2005
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1YLW
 | | X-ray structure of CTX-M-16 beta-lactamase | | 分子名称: | CTX-M-16 beta-lactamase, SULFATE ION | | 著者 | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-19 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability.
J.Mol.Biol., 348, 2005
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3RSN
 | | Crystal Structure of the N-terminal region of Human Ash2L | | 分子名称: | Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION | | 著者 | Chen, Y, Wan, B, Wang, K.C, Cao, F, Yang, Y, Protacio, A, Dou, Y, Chang, H.Y, Lei, M. | | 登録日 | 2011-05-02 | | 公開日 | 2011-06-22 | | 最終更新日 | 2011-12-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding.
Embo Rep., 12, 2011
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4L3N
 | | Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | | 著者 | Chen, Y, Rajashankar, K.R, Yang, Y, Agnihothram, S.S, Liu, C, Lin, Y.-L, Baric, R.S, Li, F. | | 登録日 | 2013-06-06 | | 公開日 | 2013-07-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Crystal structure of the receptor-binding domain from newly emerged middle East respiratory syndrome coronavirus.
J.Virol., 87, 2013
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5BUR
 | | O-succinylbenzoate Coenzyme A Synthetase (MenE) from Bacillus Subtilis, in Complex with ATP and Magnesium Ion | | 分子名称: | 1,2-ETHANEDIOL, 2-succinylbenzoate--CoA ligase, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Chen, Y, Sun, Y, Song, H, Guo, Z. | | 登録日 | 2015-06-04 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | | 主引用文献 | Structural Basis for the ATP-dependent Configuration of Adenylation Active Site in Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase
J.Biol.Chem., 290, 2015
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8F1D
 | | Voltage-gated potassium channel Kv3.1 apo | | 分子名称: | CHOLESTEROL, POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1, ... | | 著者 | Chen, Y, Ishchenko, A. | | 登録日 | 2022-11-04 | | 公開日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Identification and structural and biophysical characterization of a positive modulator of human Kv3.1 channels.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8F1C
 | | Voltage-gated potassium channel Kv3.1 with novel positive modulator (9M)-9-{5-chloro-6-[(3,3-dimethyl-2,3-dihydro-1-benzofuran-4-yl)oxy]-4-methylpyridin-3-yl}-2-methyl-7,9-dihydro-8H-purin-8-one (compound 4) | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (9M)-9-{5-chloro-6-[(3,3-dimethyl-2,3-dihydro-1-benzofuran-4-yl)oxy]-4-methylpyridin-3-yl}-2-methyl-7,9-dihydro-8H-purin-8-one, POTASSIUM ION, ... | | 著者 | Chen, Y, Ishchenko, A. | | 登録日 | 2022-11-04 | | 公開日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | | 主引用文献 | Identification and structural and biophysical characterization of a positive modulator of human Kv3.1 channels.
Proc.Natl.Acad.Sci.USA, 120, 2023
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6LQX
 | | Crystal structure of the CBP bromodomain in complex with small molecule LC-CPin7 | | 分子名称: | (1~{S},6~{R})-6-[(1-methoxycarbonyl-3,4-dihydro-2~{H}-quinolin-6-yl)carbamoyl]cyclohex-3-ene-1-carboxylic acid, CREB-binding protein, SODIUM ION | | 著者 | Chen, Y, Zhang, F, Sun, Z, Bi, X, Luo, C. | | 登録日 | 2020-01-14 | | 公開日 | 2021-01-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Design, synthesis and biological evaluation of novel small molecule inhibitor of the CBP bromodomain with possible anti-leukemia effects
To Be Published
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8DKS
 | | IRAK4 IN COMPLEX WITH COMPOUND #3 | | 分子名称: | (1S,2S,3R,4R)-3-({2-[3-(pyrrolidine-1-carbonyl)anilino]thieno[3,2-d]pyrimidin-4-yl}amino)bicyclo[2.2.1]hept-5-ene-2-carboxamide, BETA-MERCAPTOETHANOL, Interleukin-1 receptor-associated kinase 4 | | 著者 | Chen, Y, Lin, N. | | 登録日 | 2022-07-06 | | 公開日 | 2022-08-03 | | 最終更新日 | 2022-08-17 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Bicyclic pyrimidine compounds as potent IRAK4 inhibitors.
Bioorg.Med.Chem.Lett., 73, 2022
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4C0E
 | | Structure of the NOT1 superfamily homology domain from Chaetomium thermophilum | | 分子名称: | NOT1 | | 著者 | Chen, Y, Boland, A, Raisch, T, Jonas, S, Izaurralde, E, Weichenrieder, O. | | 登録日 | 2013-08-01 | | 公開日 | 2013-10-09 | | 最終更新日 | 2013-11-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure and Assembly of the not Module of the Human Ccr4-not Complex
Nat.Struct.Mol.Biol., 20, 2013
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6UED
 | | Apo Pseudomonas aeruginosa LpxD Structure | | 分子名称: | GLYCEROL, MAGNESIUM ION, UDP-3-O-acylglucosamine N-acyltransferase | | 著者 | Chen, Y, Kroeck, K, Sacco, M. | | 登録日 | 2019-09-20 | | 公開日 | 2019-11-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Discovery of dual-activity small-molecule ligands of Pseudomonas aeruginosa LpxA and LpxD using SPR and X-ray crystallography.
Sci Rep, 9, 2019
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4CRU
 | | Complex of human CNOT9 and CNOT1 including one tryptophan | | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, GLYCEROL | | 著者 | Chen, Y, Boland, A, Izaurralde, E, Weichenrieder, O. | | 登録日 | 2014-03-01 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing
Mol.Cell, 54, 2014
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4CRW
 | | Complex of human DDX6 (RECA-C) and CNOT1 (MIF4G) | | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, GLYCEROL, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 | | 著者 | Chen, Y, Boland, A, Izaurralde, E, Weichenrieder, O. | | 登録日 | 2014-03-01 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing
Mol.Cell, 54, 2014
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