6AWI
Staphylococcus aureus Type II pantothenate kinase in complex with ADP and pantothenate analog Deoxy-N5Pan
Summary for 6AWI
Entry DOI | 10.2210/pdb6awi/pdb |
Descriptor | Type II pantothenate kinase, ADENOSINE-5'-DIPHOSPHATE, (2R)-2-hydroxy-3,3-dimethyl-N-[3-oxo-3-(pentylamino)propyl]butanamide, ... (4 entities in total) |
Functional Keywords | staphylococcus aureus, sapank, adp, pantothenate analog, transferase |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 4 |
Total formula weight | 118789.42 |
Authors | Chen, Y.,Antoshchenko, T.,Strauss, E.,Barnard, L.,Huang, Y.H. (deposition date: 2017-09-05, release date: 2018-09-12, Last modification date: 2024-03-13) |
Primary citation | Chen, Y.,Antoshchenko, T.,Strauss, E.,Barnard, L.,Huang, Y.H. Structure-based identification of uncompetitive inhibitors for Staphylococcus aureus pantothenate kinase. To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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