6AWJ

Staphylococcus aureus Type II pantothenate kinase in complex with ADP and pantothenate analog Deoxy-MeO-N5Pan with pantothenate present in reaction

Summary for 6AWJ

• Entry DOI: 10.2210/pdb6awj/pdb
• Descriptor: Type II pantothenate kinase, ADENOSINE-5'-DIPHOSPHATE, (2R)-2-hydroxy-N-{3-[(5-methoxypentyl)amino]-3-oxopropyl}-3,3-dimethylbutanamide, ... (4 entities in total)
• Functional Keywords: staphylococcus aureus, sapank, adp, pantothenate analog, transferase
• Biological source: Staphylococcus aureus
• Total number of polymer chains: 4
• Total formula weight: 118909.52

Authors

Chen, Y.,Antoshchenko, T.,Strauss, E.,Barnard, L.,Huang, Y.H. (deposition date: 2017-09-05, release date: 2018-09-12, Last modification date: 2024-03-13)

• Primary citation: Chen, Y.,Antoshchenko, T.,Strauss, E.,Barnard, L.,Huang, Y.H.; Structure-based identification of uncompetitive inhibitors for Staphylococcus aureus pantothenate kinase.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)