8EAQ
 
 | | Structure of the full-length IP3R1 channel determined at high Ca2+ | | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, CALCIUM ION, Inositol 1,4,5-trisphosphate receptor type 1, ... | | 著者 | Fan, G, Baker, M.R, Terry, L.E, Arige, V, Chen, M, Seryshev, A.B, Baker, M.L, Ludtke, S.J, Yule, D.I, Serysheva, I.I. | | 登録日 | 2022-08-29 | | 公開日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Conformational motions and ligand-binding underlying gating and regulation in IP 3 R channel.
Nat Commun, 13, 2022
|
|
6PT0
 | | Cryo-EM structure of human cannabinoid receptor 2-Gi protein in complex with agonist WIN 55,212-2 | | 分子名称: | CHOLESTEROL, Cannabinoid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Xu, T.H, Xing, C, Zhuang, Y, Feng, Z, Zhou, X.E, Chen, M, Wang, L, Meng, X, Xue, Y, Wang, J, Liu, H, McGuire, T, Zhao, G, Melcher, K, Zhang, C, Xu, H.E, Xie, X.Q. | | 登録日 | 2019-07-14 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-03-04 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM Structure of the Human Cannabinoid Receptor CB2-GiSignaling Complex.
Cell, 180, 2020
|
|
2X7J
 | | Structure of the menaquinone biosynthesis protein MenD from Bacillus subtilis | | 分子名称: | 1,2-ETHANEDIOL, 2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE -1-CARBOXYLATE SYNTHASE, MANGANESE (II) ION, ... | | 著者 | Dawson, A, Chen, M, Fyfe, P.K, Guo, Z, Hunter, W.N. | | 登録日 | 2010-03-01 | | 公開日 | 2010-07-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure and Reactivity of Bacillus Subtilis Mend Catalyzing the First Committed Step in Menaquinone Biosynthesis.
J.Mol.Biol., 401, 2010
|
|
8FR7
 | | A hinge glycan regulates spike bending and impacts coronavirus infectivity | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Pintilie, G, Wilson, E, Chmielewski, D, Schmid, M.F, Jin, J, Chen, M, Singharoy, A, Chiu, W. | | 登録日 | 2023-01-06 | | 公開日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | A hinge glycan regulates spike bending and impacts coronavirus infectivity
To Be Published
|
|
8JAY
 | | CrtSPARTA Octamer bound with guide-target | | 分子名称: | DNA (25-MER), MAGNESIUM ION, Piwi domain-containing protein, ... | | 著者 | Guo, L.J, Huang, P.P, Li, Z.X, Xiao, Y.B, Chen, M.R. | | 登録日 | 2023-05-07 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
Nat.Chem.Biol., 20, 2024
|
|
6L30
 | | Crystal structure of the epithelial cell transforming 2 (ECT2) | | 分子名称: | Protein ECT2 | | 著者 | Chen, Z.C, Chen, M.R, Pan, H, Sun, L.F, Shi, P. | | 登録日 | 2019-10-07 | | 公開日 | 2020-01-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure and regulation of human epithelial cell transforming 2 protein.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
8FCG
 | | Cryo-EM structure of Chikungunya virus asymmetric unit | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Capsid protein, E1 glycoprotein, ... | | 著者 | Su, G.C, Chmielewsk, D, Kaelber, J, Pintilie, G, Chen, M, Jin, J, Auguste, A, Chiu, W. | | 登録日 | 2022-12-01 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Cryogenic electron microscopy and tomography reveal imperfect icosahedral symmetry in alphaviruses.
Pnas Nexus, 3, 2024
|
|
4H00
 | | The crystal structure of mon-Zn dihydropyrimidinase from Tetraodon nigroviridis | | 分子名称: | ZINC ION, dihydropyrimidinase | | 著者 | Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. | | 登録日 | 2012-09-06 | | 公開日 | 2013-09-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Lysine Carboxylation: Metal and Structural Requirements for Post-translational Modification
To be Published
|
|
4GZ7
 | | The crystal structure of Apo-dihydropyrimidinase from Tetraodon nigroviridis | | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, dihydropyrimidinase | | 著者 | Hsien, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. | | 登録日 | 2012-09-06 | | 公開日 | 2013-09-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Lysine Carboxylation: Metal and Structure Requirements for Post-translational Modification
To be Published
|
|
4H01
 | | The crystal structure of di-Zn dihydropyrimidinase from Tetraodon nigroviridis | | 分子名称: | ZINC ION, dihydropyrimidinase | | 著者 | Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. | | 登録日 | 2012-09-06 | | 公開日 | 2013-09-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Lysine Carboxylation: Metal and Structural Requirements for Post-translational Modification
To be Published
|
|
8J84
 | | Short ago complexed with TIR-APAZ | | 分子名称: | Piwi domain-containing protein, TIR domain-containing protein | | 著者 | Guo, L.J, Huang, P.P, Li, Z.X, Xiao, Y.B, Chen, M.R. | | 登録日 | 2023-04-30 | | 公開日 | 2024-03-13 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
Nat.Chem.Biol., 20, 2024
|
|
8J9G
 | | CrtSPARTA hetero-dimer bound with guide-target, state 1 | | 分子名称: | DNA (25-MER), MAGNESIUM ION, Piwi domain-containing protein, ... | | 著者 | Li, Z.X, Guo, L.J, Huang, P.P, Xiao, Y.B, Chen, M.R. | | 登録日 | 2023-05-03 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
Nat.Chem.Biol., 20, 2024
|
|
8J8H
 | | SPARTA monomer bound with guide-target, state 2 | | 分子名称: | DNA (25-MER), MAGNESIUM ION, Piwi domain-containing protein, ... | | 著者 | Li, Z.X, Guo, L.J, Huang, P.P, Xiao, Y.B, Chen, M.R. | | 登録日 | 2023-05-01 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
Nat.Chem.Biol., 20, 2024
|
|
8J9P
 | | SPARTA dimer bound with guide-target | | 分子名称: | DNA (25-MER), MAGNESIUM ION, Piwi domain-containing protein, ... | | 著者 | Li, Z.X, Guo, L.J, Huang, P.P, Xiao, Y.B, Chen, M.R. | | 登録日 | 2023-05-04 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
Nat.Chem.Biol., 20, 2024
|
|
4LCQ
 | | The crystal structure of di-Zn dihydropyrimidinase in complex with NCBI | | 分子名称: | (2S)-3-(carbamoylamino)-2-methylpropanoic acid, ZINC ION, dihydropyrimidinase | | 著者 | Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. | | 登録日 | 2013-06-22 | | 公開日 | 2013-09-18 | | 最終更新日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function.
J.Biol.Chem., 288, 2013
|
|
4LCR
 | | The crystal structure of di-Zn dihydropyrimidinase in complex with NCBA | | 分子名称: | Chromosome 8 SCAF14545, whole genome shotgun sequence, N-(AMINOCARBONYL)-BETA-ALANINE, ... | | 著者 | Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. | | 登録日 | 2013-06-22 | | 公開日 | 2013-09-18 | | 最終更新日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function.
J.Biol.Chem., 288, 2013
|
|
5WSL
 | | Structural studies of keratinase from Meiothermus taiwanensis WR-220 | | 分子名称: | CALCIUM ION, SULFATE ION, keratinase | | 著者 | Ho, M.C, Wu, S.H, Chen, M.Y, Tu, I.F. | | 登録日 | 2016-12-07 | | 公開日 | 2017-10-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The discovery of novel heat-stable keratinases from Meiothermus taiwanensis WR-220 and other extremophiles
Sci Rep, 7, 2017
|
|
2ALF
 | | crystal structure of human CypA mutant K131A | | 分子名称: | MAGNESIUM ION, Peptidyl-prolyl cis-trans isomerase A | | 著者 | Hu, H, Huang, C.-Q, Liu, H.-L, Han, Y, Chen, M.-E, Yu, L, Bi, R.-C. | | 登録日 | 2005-08-05 | | 公開日 | 2005-08-23 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Nuclease activity of Cyclophilin A and its structural basis
TO BE PUBLISHED
|
|
3IXT
 | | Crystal Structure of Motavizumab Fab Bound to Peptide Epitope | | 分子名称: | 1,2-ETHANEDIOL, Fusion glycoprotein F1, Motavizumab Fab heavy chain, ... | | 著者 | McLellan, J.S, Chen, M, Kim, A, Yang, Y, Graham, B.S, Kwong, P.D. | | 登録日 | 2009-09-04 | | 公開日 | 2010-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural basis of respiratory syncytial virus neutralization by motavizumab.
Nat.Struct.Mol.Biol., 17, 2010
|
|
4LCS
 | | The crystal structure of di-Zn dihydropyrimidinase in complex with hydantoin | | 分子名称: | Chromosome 8 SCAF14545, whole genome shotgun sequence, ZINC ION, ... | | 著者 | Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S. | | 登録日 | 2013-06-23 | | 公開日 | 2013-09-18 | | 最終更新日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function.
J.Biol.Chem., 288, 2013
|
|
7Y71
 | | SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab E7 heavy chain, ... | | 著者 | Chia, W.N, Tan, C.W, Tan, A.W.K, Young, B, Starr, T.N, Lopez, E, Fibriansah, G, Barr, J, Cheng, S, Yeoh, A.Y.Y, Yap, W.C, Lim, B.L, Ng, T.S, Sia, W.R, Zhu, F, Chen, S, Zhang, J, Greaney, A.J, Chen, M, Au, G.G, Paradkar, P, Peiris, M, Chung, A.W, Bloom, J.D, Lye, D, Lok, S.M, Wang, L.F. | | 登録日 | 2022-06-21 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor.
Sci Adv, 9, 2023
|
|
7Y72
 | | SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 (focused refinement on Fab-RBD interface) | | 分子名称: | Fab E7 heavy chain, Fab E7 light chain, Spike glycoprotein | | 著者 | Chia, W.N, Tan, C.W, Tan, A.W.K, Young, B, Starr, T.N, Lopez, E, Fibriansah, G, Barr, J, Cheng, S, Yeoh, A.Y.Y, Yap, W.C, Lim, B.L, Ng, T.S, Sia, W.R, Zhu, F, Chen, S, Zhang, J, Greaney, A.J, Chen, M, Au, G.G, Paradkar, P, Peiris, M, Chung, A.W, Bloom, J.D, Lye, D, Lok, S.M, Wang, L.F. | | 登録日 | 2022-06-21 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | | 主引用文献 | Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor.
Sci Adv, 9, 2023
|
|
3O45
 | | Crystal Structure of 101F Fab Bound to 17-mer Peptide Epitope | | 分子名称: | Fusion glycoprotein F1, Mouse monoclonal antibody 101F 101F Fab heavy chain, Mouse monoclonal antibody 101F 101F Fab light chain, ... | | 著者 | McLellan, J.S, Chen, M, Chang, J.S, Yang, Y, Kim, A, Graham, B.S, Kwong, P.D. | | 登録日 | 2010-07-26 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.872 Å) | | 主引用文献 | Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F.
J.Virol., 84, 2010
|
|
3O41
 | | Crystal Structure of 101F Fab Bound to 15-mer Peptide Epitope | | 分子名称: | Fusion glycoprotein F1, Mouse monoclonal antibody 101F Fab heavy chain, Mouse monoclonal antibody 101F Fab light chain, ... | | 著者 | McLellan, J.S, Chen, M, Chang, J.S, Yang, Y, Kim, A, Graham, B.S, Kwong, P.D. | | 登録日 | 2010-07-26 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F.
J.Virol., 84, 2010
|
|
3JBB
 | | Characterization of red-shifted phycobiliprotein complexes isolated from the chlorophyll f-containing cyanobacterium Halomicronema hongdechloris | | 分子名称: | PHYCOCYANOBILIN, SULFATE ION, allophycocyanin beta chain, ... | | 著者 | Li, Y, Lin, Y, Garvey, C, Birch, D, Corkery, R.W, Loughlin, P.C, Scheer, H, Willows, R.D, Chen, M. | | 登録日 | 2015-08-26 | | 公開日 | 2015-11-11 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (26 Å) | | 主引用文献 | Characterization of red-shifted phycobilisomes isolated from the chlorophyll f-containing cyanobacterium Halomicronema hongdechloris.
Biochim.Biophys.Acta, 1857, 2015
|
|
