8J9P
SPARTA dimer bound with guide-target
Summary for 8J9P
Entry DOI | 10.2210/pdb8j9p/pdb |
EMDB information | 36114 |
Descriptor | Piwi domain-containing protein, TIR domain-containing protein, RNA (5'-R(P*UP*GP*AP*CP*GP*GP*CP*UP*CP*UP*AP*AP*UP*CP*UP*AP*UP*UP*AP*GP*U)-3'), ... (5 entities in total) |
Functional Keywords | sparta, ago, tir, dna binding protein/rna/dna, dna binding protein-rna-dna complex |
Biological source | Thermoflavifilum thermophilum More |
Total number of polymer chains | 8 |
Total formula weight | 251825.67 |
Authors | Li, Z.X.,Guo, L.J.,Huang, P.P.,Xiao, Y.B.,Chen, M.R. (deposition date: 2023-05-04, release date: 2024-03-06, Last modification date: 2024-04-10) |
Primary citation | Guo, L.,Huang, P.,Li, Z.,Shin, Y.C.,Yan, P.,Lu, M.,Chen, M.,Xiao, Y. Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system. Nat.Chem.Biol., 20:512-520, 2024 Cited by PubMed: 37932527DOI: 10.1038/s41589-023-01478-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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