7D5C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d5c by Molmil](/molmil-images/mine/7d5c) | IleRS in complex with a tRNA site inhibitor | 分子名称: | (2E,4S,5S,6E,8E)-10-[(2S,3R,6S,8R,9S)-3-butyl-9-methyl-2-[(1E,3E)-3-methyl-5-oxidanyl-5-oxidanylidene-penta-1,3-dienyl]-3-(4-oxidanyl-4-oxidanylidene-butanoyl)oxy-1,7-dioxaspiro[5.5]undecan-8-yl]-4,8-dimethyl-5-oxidanyl-deca-2,6,8-trienoic acid, 1,2-ETHANEDIOL, Isoleucine--tRNA ligase, ... | 著者 | Chen, B, Luo, S, Zhou, H. | 登録日 | 2020-09-25 | 公開日 | 2021-02-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | 主引用文献 | Inhibitory mechanism of reveromycin A at the tRNA binding site of a class I synthetase. Nat Commun, 12, 2021
|
|
2BF1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bf1 by Molmil](/molmil-images/mine/2bf1) | Structure of an unliganded and fully-glycosylated SIV gp120 envelope glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chen, B, Vogan, E.M, Gong, H, Skehel, J.J, Wiley, D.C, Harrison, S.C. | 登録日 | 2004-12-02 | 公開日 | 2005-02-17 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Structure of an Unliganded Simian Immunodeficiency Virus Gp120 Core Nature, 433, 2005
|
|
8YY8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yy8 by Molmil](/molmil-images/mine/8yy8) | Fzd7 -Gs complex | 分子名称: | Frizzled-7, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Chen, B, Xu, L, Han, G.W, Xu, F. | 登録日 | 2024-04-03 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G s . Cell Res., 31, 2021
|
|
7UBX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ubx by Molmil](/molmil-images/mine/7ubx) | |
7UBY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uby by Molmil](/molmil-images/mine/7uby) | Structure of the GTD domain of Clostridium difficile toxin A in complex with VHH AH3 | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Glucosyltransferase TcdA, ... | 著者 | Chen, B, Rongsheng, J, Kay, P. | 登録日 | 2022-03-15 | 公開日 | 2022-11-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Neutralizing epitopes on Clostridioides difficile toxin A revealed by the structures of two camelid VHH antibodies. Front Immunol, 13, 2022
|
|
1ZA8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1za8 by Molmil](/molmil-images/mine/1za8) | NMR solution structure of a leaf-specific-expressed cyclotide vhl-1 | 分子名称: | vhl-1 | 著者 | Chen, B, Colgrave, M.L, Daly, N.L, Rosengren, K.J, Gustafson, K.R, Craik, D.J. | 登録日 | 2005-04-05 | 公開日 | 2005-04-12 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Isolation and characterization of novel cyclotides from Viola hederaceae: solution structure and anti-HIV activity of vhl-1, a leaf-specific expressed cyclotide. J.Biol.Chem., 280, 2005
|
|
2L0K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l0k by Molmil](/molmil-images/mine/2l0k) | NMR solution structure of a transcription factor SpoIIID in complex with DNA | 分子名称: | Stage III sporulation protein D | 著者 | Chen, B, Himes, P, Lu, Z, Liu, A, Yan, H, Kroos, L. | 登録日 | 2010-07-08 | 公開日 | 2011-08-17 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Novel Mode of DNA Binding by Bacterial Transcription Factor SpoIIID To be Published
|
|
4MG2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mg2 by Molmil](/molmil-images/mine/4mg2) | ALKBH2 F102A cross-linked to undamaged dsDNA | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA-1, DNA-2, ... | 著者 | Chen, B, Gan, J, Yang, C.G. | 登録日 | 2013-08-28 | 公開日 | 2014-02-26 | 最終更新日 | 2014-06-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The complex structures of ALKBH2 mutants cross-linked to
dsDNA reveal the conformational swing of β-hairpin Sci China Chem, 57, 2014
|
|
4MGT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mgt by Molmil](/molmil-images/mine/4mgt) | ALKBH2 R110A cross-linked to undamaged dsDNA | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA1, DNA2, ... | 著者 | Chen, B, Gan, J, Yang, C.G. | 登録日 | 2013-08-28 | 公開日 | 2014-02-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The complex structures of ALKBH2 mutants cross-linked to
dsDNA reveal the conformational swing of β-hairpin Sci China Chem, 57, 2014
|
|
8HMP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hmp by Molmil](/molmil-images/mine/8hmp) | GPR52 with Gs and c17 | 分子名称: | G-protein coupled receptor 52, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Chen, B, Xu, F. | 登録日 | 2022-12-05 | 公開日 | 2023-06-21 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Allosteric coupling between G-protein binding and extracellular ligand binding sites in GPR52 revealed by 19 F-NMR and cryo-electron microscopy. MedComm (2020), 4, 2023
|
|
3M0E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3m0e by Molmil](/molmil-images/mine/3m0e) | Crystal structure of the ATP-bound state of Walker B mutant of NtrC1 ATPase domain | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Transcriptional regulator (NtrC family) | 著者 | Chen, B, Sysoeva, T.A, Chowdhury, S, Rusu, M, Birmanns, S, Guo, L, Hanson, J, Yang, H, Nixon, B.T. | 登録日 | 2010-03-02 | 公開日 | 2010-11-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Engagement of Arginine Finger to ATP Triggers Large Conformational Changes in NtrC1 AAA+ ATPase for Remodeling Bacterial RNA Polymerase. Structure, 18, 2010
|
|
8HJ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hj2 by Molmil](/molmil-images/mine/8hj2) | GPR21 wt with G15 complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Chen, B, Lin, X, Xu, F. | 登録日 | 2022-11-22 | 公開日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
|
|
8HJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hj0 by Molmil](/molmil-images/mine/8hj0) | GPR21(m5) and G15 complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Chen, B, Lin, X. | 登録日 | 2022-11-22 | 公開日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
|
|
8HIX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hix by Molmil](/molmil-images/mine/8hix) | Cryo-EM structure of GPR21_m5_Gs | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Chen, B, Lin, X, Xu, F. | 登録日 | 2022-11-22 | 公開日 | 2023-03-15 | 最終更新日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
|
|
8HJ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hj1 by Molmil](/molmil-images/mine/8hj1) | GPR21(wt) and Gs complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Chen, B, Lin, X, Xu, F. | 登録日 | 2022-11-22 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
|
|
5YHU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yhu by Molmil](/molmil-images/mine/5yhu) | |
5ZHU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zhu by Molmil](/molmil-images/mine/5zhu) | |
5ZNK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5znk by Molmil](/molmil-images/mine/5znk) | Crystal structure of a bacterial ProRS with ligands | 分子名称: | 7-chloro-6-fluoro-3-{2-oxo-3-[(2S)-piperidin-2-yl]propyl}quinazolin-4(3H)-one, GLYCEROL, MAGNESIUM ION, ... | 著者 | Cheng, B, Yu, Y, Zhou, H. | 登録日 | 2018-04-09 | 公開日 | 2019-05-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Structure-Guided Design of Halofuginone Derivatives as ATP-Aided Inhibitors Against Bacterial Prolyl-tRNA Synthetase. J.Med.Chem., 65, 2022
|
|
5ZNJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5znj by Molmil](/molmil-images/mine/5znj) | Crystal structure of a bacterial ProRS with ligands | 分子名称: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, GLYCEROL, MAGNESIUM ION, ... | 著者 | Cheng, B, Yu, Y, Zhou, H. | 登録日 | 2018-04-09 | 公開日 | 2019-05-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structure-Guided Design of Halofuginone Derivatives as ATP-Aided Inhibitors Against Bacterial Prolyl-tRNA Synthetase. J.Med.Chem., 65, 2022
|
|
5ZAN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zan by Molmil](/molmil-images/mine/5zan) | |
3VPN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3vpn by Molmil](/molmil-images/mine/3vpn) | Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant | 分子名称: | FE (III) ION, MAGNESIUM ION, Ribonucleoside-diphosphate reductase subunit M2 | 著者 | Chen, X, Xu, Z, Liu, H, Zhang, L, Chen, B, Zhu, L, Yang, C, Zhu, W, Shao, J. | 登録日 | 2012-03-05 | 公開日 | 2013-03-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Essential role of E106 in the proton-coupled electron transfer in human to be published
|
|
3VPM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3vpm by Molmil](/molmil-images/mine/3vpm) | Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant | 分子名称: | FE (III) ION, MAGNESIUM ION, Ribonucleoside-diphosphate reductase subunit M2 | 著者 | Chen, X, Xu, Z, Liu, H, Zhang, L, Chen, B, Zhu, L, Yang, C, Zhu, W, Shao, J. | 登録日 | 2012-03-05 | 公開日 | 2013-03-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Essential role of E106 in the proton-coupled electron transfer in human ribonucleotide reductase M2 subunit To be Published
|
|
3VPO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3vpo by Molmil](/molmil-images/mine/3vpo) | Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant | 分子名称: | FE (III) ION, MAGNESIUM ION, Ribonucleoside-diphosphate reductase subunit M2 | 著者 | Chen, X, Xu, Z, Liu, H, Zhang, L, Chen, B, Zhu, L, Yang, C, Zhu, W, Shao, J. | 登録日 | 2012-03-05 | 公開日 | 2013-03-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Essential role of E106 in the proton-coupled electron transfer in human to be published
|
|
4V94
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v94 by Molmil](/molmil-images/mine/4v94) | Molecular architecture of the eukaryotic chaperonin TRiC/CCT derived by a combination of chemical crosslinking and mass-spectrometry, XL-MS | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Leitner, A, Joachimiak, L.A, Bracher, A, Walzthoeni, T, Chen, B, Monkemeyer, L, Pechmann, S, Holmes, S, Cong, Y, Ma, B, Ludtke, S, Chiu, W, Hartl, F.U, Aebersold, R, Frydman, J. | 登録日 | 2012-01-11 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | The Molecular Architecture of the Eukaryotic Chaperonin TRiC/CCT. Structure, 20, 2012
|
|
6XR8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xr8 by Molmil](/molmil-images/mine/6xr8) | Distinct conformational states of SARS-CoV-2 spike protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Rawson, S, Volloch, S.R, Chen, B. | 登録日 | 2020-07-11 | 公開日 | 2020-07-22 | 最終更新日 | 2020-11-25 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Distinct conformational states of SARS-CoV-2 spike protein. Science, 369, 2020
|
|