8YY8

Fzd7 -Gs complex

Replaces:  7EVW

Summary for 8YY8

• Entry DOI: 10.2210/pdb8yy8/pdb
• EMDB information: 31340
• Descriptor: minGas, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total)
• Functional Keywords: gpcr, class f, frizzled, fzd7, frizzled 7, membrane protein, fzd7-gs complex
• Biological source: Homo sapiens; More
• Total number of polymer chains: 5
• Total formula weight: 158959.15

Authors

Chen, B.,Xu, L.,Han, G.W.,Xu, F. (deposition date: 2024-04-03, release date: 2024-04-24, Last modification date: 2024-10-16)

• Primary citation: Xu, L.,Chen, B.,Schihada, H.,Wright, S.C.,Turku, A.,Wu, Y.,Han, G.W.,Kowalski-Jahn, M.,Kozielewicz, P.,Bowin, C.F.,Zhang, X.,Li, C.,Bouvier, M.,Schulte, G.,Xu, F.; Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G s .; Cell Res., 31:1311-1314, 2021; PubMed: 34239071; DOI: 10.1038/s41422-021-00525-6

Experimental method

ELECTRON MICROSCOPY (3.22 Å)