7UBY

Structure of the GTD domain of Clostridium difficile toxin A in complex with VHH AH3

Summary for 7UBY

• Entry DOI: 10.2210/pdb7uby/pdb
• Descriptor: Glucosyltransferase TcdA, Nanobody VHH AH3, URIDINE-5'-DIPHOSPHATE-GLUCOSE, ... (7 entities in total)
• Functional Keywords: gtd, neutralizing antibody, toxin
• Biological source: Clostridioides difficile; More
• Total number of polymer chains: 4
• Total formula weight: 160203.43

Authors

Chen, B.,Rongsheng, J.,Kay, P. (deposition date: 2022-03-15, release date: 2022-11-16, Last modification date: 2023-10-25)

• Primary citation: Chen, B.,Perry, K.,Jin, R.; Neutralizing epitopes on Clostridioides difficile toxin A revealed by the structures of two camelid VHH antibodies.; Front Immunol, 13:978858-978858, 2022; PubMed: 36466927; DOI: 10.3389/fimmu.2022.978858

Experimental method

X-RAY DIFFRACTION (2.1 Å)