7UBY
Structure of the GTD domain of Clostridium difficile toxin A in complex with VHH AH3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (B, A) | Glucosyltransferase TcdA | polymer | 543 | 62919.0 | 2 | UniProt (P16154) Pfam (PF12918) Pfam (PF12919) | Clostridioides difficile | |
| 2 | B, D (D, C) | Nanobody VHH AH3 | polymer | 151 | 16114.0 | 2 | Camelidae | ||
| 3 | E, M (B, A) | URIDINE-5'-DIPHOSPHATE-GLUCOSE | non-polymer | 566.3 | 2 | Chemie (UPG) | |||
| 4 | F, N (B, A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | G, H (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | I, J, K, L, O... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
| 7 | V, W, X, Y (B, D, A, C) | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 542 (UniProt: P16154)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Ala 190 | Lys 190 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 158066.0 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2137.5 | |
| All* | Total formula weight | 160203.4 |
