7UBY
Structure of the GTD domain of Clostridium difficile toxin A in complex with VHH AH3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (B, A) | Glucosyltransferase TcdA | polymer | 543 | 62919.0 | 2 | UniProt (P16154) | Clostridioides difficile | |
| 2 | B, D (D, C) | Nanobody VHH AH3 | polymer | 151 | 16114.0 | 2 | Camelidae | ||
| 3 | E, M (B, A) | URIDINE-5'-DIPHOSPHATE-GLUCOSE | non-polymer | 566.3 | 2 | Chemie (UPG) PubChem (16667381) PubChem (20776702) PubChem (20776703) PubChem (25011746) PubChem (16760700) PubChem (20776705) PubChem (20776706) PubChem (23724458) PubChem (56650783) PubChem (56846106) PubChem (45109771) PubChem (46226441) PubChem (8629) PubChem (18068) PubChem (439158) PubChem (448873) PubChem (46936243) PubChem (640055) PubChem (92328335) PubChem (92974127) PubChem (6857410) PubChem (53477679) PubChem (124933210) PubChem (129850353) PubChem (11734460) PubChem (56845790) PubChem (155893098) PubChem (158571248) PubChem (162920685) PubChem (58538034) PubChem (168265389) PubChem (59720988) PubChem (88869506) PubChem (88869507) PubChem (88869743) PubChem (88870643) PubChem (88883029) PubChem (88910951) PubChem (88941526) PubChem (89321600) PubChem (89360378) PubChem (89847362) PubChem (90056247) PubChem (90950359) PubChem (91746280) PubChem (92974126) PubChem (92974128) PubChem (92974129) PubChem (93535589) PubChem (102429624) PubChem (1166) PubChem (439156) PubChem (448801) PubChem (124933209) PubChem (6857540) PubChem (12133414) PubChem (13008857) PubChem (13987142) PubChem (134736387) PubChem (134736388) PubChem (138911444) PubChem (162920683) PubChem (162920684) PubChem (163626061) PubChem (166642644) PubChem (168720052) PubChem (174027848) | |||
| 4 | F, N (B, A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) PubChem (27854) | |||
| 5 | G, H (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) PubChem (8117) | |||
| 6 | I, J, K, L, O... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
| 7 | V, W, X, Y (B, D, A, C) | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 542 (UniProt: P16154)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Ala 190 | Lys 190 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 158066.0 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2137.5 | |
| All* | Total formula weight | 160203.4 |
