1C6V
 
 | | SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H) | | 分子名称: | PROTEIN (SIU89134), PROTEIN (SIV INTEGRASE) | | 著者 | Chen, Z, Yan, Y, Munshi, S, Li, Y, Zruygay-Murphy, J, Xu, B, Witmer, M, Felock, P, Wolfe, A, Sardana, V, Emini, E.A, Hazuda, D, Kuo, L.C. | | 登録日 | 1999-12-21 | | 公開日 | 2000-12-27 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform.
J.Mol.Biol., 296, 2000
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3N9H
 | | Crystal Structural of mutant Y305A in the copper amine oxidase from hansenula polymorpha | | 分子名称: | COPPER (II) ION, Peroxisomal primary amine oxidase | | 著者 | Chen, Z, Datta, S, DuBois, J.L, Klinman, J.P, Mathews, F.S. | | 登録日 | 2010-05-30 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity.
Biochemistry, 49, 2010
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3NBB
 | | Crystal structure of mutant Y305F expressed in E. coli in the copper amine oxidase from hansenula polymorpha | | 分子名称: | COPPER (II) ION, Peroxisomal primary amine oxidase | | 著者 | Chen, Z, Datta, S, DuBois, J.L, Klinman, J.P, Mathews, F.S. | | 登録日 | 2010-06-03 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity.
Biochemistry, 49, 2010
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2GC4
 | | Structural comparison of the oxidized ternary electron transfer complex of methylamine dehydrogenase, amicyanin and cytochrome c551i from Paracoccus denitrificans with the substrate-reduced, copper free complex at 1.9 A resolution. | | 分子名称: | Amicyanin, COPPER (II) ION, Cytochrome c-L, ... | | 著者 | Chen, Z, Durley, R, Davidson, V.L, Mathews, F.S. | | 登録日 | 2006-03-13 | | 公開日 | 2006-11-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural comparison of the oxidized ternary electron transfer complex of methylamine dehydrogenase, amicyanin and cytochrome c551i from Paracoccus denitrificans with the substrate-reduced, copper free complex at 1.9 A resolution.
To be Published
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1AHT
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3NXP
 | | Crystal structure of human prethrombin-1 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | 著者 | Chen, Z, Bush-Pelc, L.A, Di Cera, E. | | 登録日 | 2010-07-14 | | 公開日 | 2010-11-10 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of prethrombin-1.
Proc.Natl.Acad.Sci.USA, 107, 2010
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6LOH
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7VDV
 | | The overall structure of human chromatin remodeling PBAF-nucleosome complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2,AT-rich interactive domain-containing protein 2, Actin, ... | | 著者 | Chen, Z.C, Chen, K.J, Yuan, J.J. | | 登録日 | 2021-09-07 | | 公開日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Nature, 605, 2022
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5IXY
 | | Lactate Dehydrogenase in complex with hydroxylactam inhibitor compound 31: (2~{S})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one | | 分子名称: | (2~{S})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one, L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Chen, Z, Eigenbrot, C. | | 登録日 | 2016-03-23 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice.
Acs Med.Chem.Lett., 7, 2016
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7VDT
 | | The motor-nucleosome module of human chromatin remodeling PBAF-nucleosome complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (207-MER), ... | | 著者 | Chen, Z.C, Chen, K.J, Yuan, J.J. | | 登録日 | 2021-09-07 | | 公開日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Nature, 605, 2022
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5J9U
 | | Crystal structure of the NuA4 core complex | | 分子名称: | Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, Enhancer of polycomb-like protein 1, ... | | 著者 | Chen, Z.C, Xu, P. | | 登録日 | 2016-04-11 | | 公開日 | 2016-10-26 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Mol.Cell, 63, 2016
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4OVA
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6BC0
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6BC1
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1TOM
 | | ALPHA-THROMBIN COMPLEXED WITH HIRUGEN | | 分子名称: | ALPHA-THROMBIN, HIRUGEN, METHYL-PHE-PRO-AMINO-CYCLOHEXYLGLYCINE | | 著者 | Chen, Z. | | 登録日 | 1996-12-06 | | 公開日 | 1997-03-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Synthesis, evaluation, and crystallographic analysis of L-371,912: A potent and selective active-site thrombin inhibitor.
Bioorg.Med.Chem.Lett., 7, 1997
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5J9Q
 | | Crystal structure of the NuA4 core complex | | 分子名称: | Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, Enhancer of polycomb-like protein 1, ... | | 著者 | Chen, Z.C, Xu, P. | | 登録日 | 2016-04-11 | | 公開日 | 2016-10-26 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Mol.Cell, 63, 2016
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6JDX
 | | Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 preprocessed with protease alpha-Chymotrypsin | | 分子名称: | 1,2-ETHANEDIOL, AcrIIC2, CRISPR-associated endonuclease Cas9 | | 著者 | Cheng, Z, Huang, X, Sun, W, Wang, Y. | | 登録日 | 2019-02-02 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
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5H5Z
 | | Crystal structure of bony fish MHC class I, peptide and B2m II | | 分子名称: | Beta-2-microglobulin, MHC class I antigen, peptide chain | | 著者 | Chen, Z, Zhang, N, Qi, J, Li, X, Chen, R, Wang, Z, Gao, F.G, Xia, C. | | 登録日 | 2016-11-10 | | 公開日 | 2017-11-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | The Mechanism of beta 2m Molecule-Induced Changes in the Peptide Presentation Profile in a Bony Fish.
Iscience, 23, 2020
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5J9W
 | | Crystal structure of the NuA4 core complex | | 分子名称: | ACETYL COENZYME *A, Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, ... | | 著者 | Chen, Z.C, Xu, P. | | 登録日 | 2016-04-11 | | 公開日 | 2016-10-26 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Mol.Cell, 63, 2016
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6JDJ
 | | Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 | | 分子名称: | AcrIIC2, CRISPR-associated endonuclease Cas9 | | 著者 | Cheng, Z, Huang, X, Sun, W, Wang, Y. | | 登録日 | 2019-02-01 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
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6AZE
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5J9T
 | | Crystal structure of the NuA4 core complex | | 分子名称: | Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, Enhancer of polycomb-like protein 1, ... | | 著者 | Chen, Z.C, Xu, P. | | 登録日 | 2016-04-11 | | 公開日 | 2016-10-26 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Mol.Cell, 63, 2016
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1FCD
 | | THE STRUCTURE OF FLAVOCYTOCHROME C SULFIDE DEHYDROGENASE FROM A PURPLE PHOTOTROPHIC BACTERIUM CHROMATIUM VINOSUM AT 2.5 ANGSTROMS RESOLUTION | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C SULFIDE DEHYDROGENASE (CYTOCHROME SUBUNIT), FLAVOCYTOCHROME C SULFIDE DEHYDROGENASE (FLAVIN-BINDING SUBUNIT), ... | | 著者 | Chen, Z.W, Koh, M, Van Driessche, G, Van Beeumen, J.J, Bartsch, R.G, Meyer, T.E, Cusanovich, M.A, Mathews, F.S. | | 登録日 | 1994-08-18 | | 公開日 | 1994-11-01 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | The structure of flavocytochrome c sulfide dehydrogenase from a purple phototrophic bacterium.
Science, 266, 1994
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6JD7
 | | Crystal structure of anti-CRISPR protein AcrIIC2 dimer | | 分子名称: | ACETATE ION, AcrIIC2, MAGNESIUM ION | | 著者 | Cheng, Z, Huang, X, Sun, W, Wang, Y.L. | | 登録日 | 2019-01-31 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
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2A89
 | | Monomeric Sarcosine Oxidase: Structure of a covalently flavinylated amine oxidizing enzyme | | 分子名称: | (N5,C4A)-(ALPHA-HYDROXY-PROPANO)-3,4,4A,5-TETRAHYDRO-FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, Monomeric sarcosine oxidase, ... | | 著者 | Chen, Z.-W, Zhao, G, Martinovic, S, Jorns, M.S, Mathews, F.S. | | 登録日 | 2005-07-07 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure of the sodium borohydride-reduced N-(cyclopropyl)glycine adduct of the flavoenzyme monomeric sarcosine oxidase.
Biochemistry, 44, 2005
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