3B3X
 
 | | Crystal structure of class A beta-lactamase of Bacillus licheniformis BS3 with aminocitrate | | 分子名称: | 2-(carboxymethyl)-D-aspartic acid, Beta-lactamase | | 著者 | Sauvage, E, Herman, R, Kerff, F, Charlier, P. | | 登録日 | 2007-10-23 | | 公開日 | 2007-11-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | 2-Aminopropane-1,2,3-tricarboxylic acid: Synthesis and co-crystallization with the class A beta-lactamase BS3 of Bacillus licheniformis
Bioorg.Med.Chem.Lett., 18, 2008
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1XPB
 | | STRUCTURE OF BETA-LACTAMASE TEM1 | | 分子名称: | BETA-LACTAMASE, SULFATE ION | | 著者 | Fonze, E, Charlier, P. | | 登録日 | 1997-01-10 | | 公開日 | 1997-04-01 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | TEM1 beta-lactamase structure solved by molecular replacement and refined structure of the S235A mutant.
Acta Crystallogr.,Sect.D, 51, 1995
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3D2Z
 | | Complex of the N-acetylmuramyl-L-alanine amidase AmiD from E.coli with the product L-Ala-D-gamma-Glu-L-Lys | | 分子名称: | CHLORIDE ION, L-Ala-D-gamma-Glu-L-Lys peptide, N-acetylmuramoyl-L-alanine amidase amiD, ... | | 著者 | Kerff, F, Petrella, S, Herman, R, Sauvage, E, Mercier, F, Luxen, A, Frere, J.M, Joris, B, Charlier, P. | | 登録日 | 2008-05-09 | | 公開日 | 2009-06-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Specific Structural Features of the N-Acetylmuramoyl-l-Alanine Amidase AmiD from Escherichia coli and Mechanistic Implications for Enzymes of This Family.
J.Mol.Biol., 397, 2010
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3D2Y
 | | Complex of the N-acetylmuramyl-L-alanine amidase AmiD from E.coli with the substrate anhydro-N-acetylmuramic acid-L-Ala-D-gamma-Glu-L-Lys | | 分子名称: | Anhydro-N-acetylmuramic acid-L-Ala-D-gamma-Glu-L-Lys, GLYCEROL, N-acetylmuramoyl-L-alanine amidase amiD | | 著者 | Kerff, F, Petrella, S, Herman, R, Sauvage, E, Mercier, F, Luxen, A, Frere, J.M, Joris, B, Charlier, P. | | 登録日 | 2008-05-09 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Specific Structural Features of the N-Acetylmuramoyl-l-Alanine Amidase AmiD from Escherichia coli and Mechanistic Implications for Enzymes of This Family.
J.Mol.Biol., 397, 2010
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1Y54
 | | Crystal structure of the native class C beta-lactamase from Enterobacter cloacae 908R complexed with BRL42715 | | 分子名称: | (7R)-6-FORMYL-7-(1-METHYL-1H-1,2,3-TRIAZOL-4-YL)-4,7-DIHYDRO-1,4-THIAZEPINE-3-CARBOXYLIC ACID, Beta-lactamase | | 著者 | Michaux, C, Charlier, P, Frere, J.-M, Wouters, J. | | 登録日 | 2004-12-02 | | 公開日 | 2005-03-29 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of BRL 42715, C6-(N1-Methyl-1,2,3-triazolylmethylene)penem, in Complex with Enterobactercloacae 908R beta-Lactamase: Evidence for a Stereoselective Mechanism from Docking Studies
J.Am.Chem.Soc., 127, 2005
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1K38
 | | CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-2 | | 分子名称: | Beta-lactamase OXA-2, FORMIC ACID | | 著者 | Kerff, F, Fonze, E, Bouillenne, F, Frere, J.M, Charlier, P. | | 登録日 | 2001-10-02 | | 公開日 | 2003-06-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-2
To be Published
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6Y6L
 | | Structure the ananain protease from Ananas comosus with a thiomethylated catalytic cysteine | | 分子名称: | Ananain, GLYCEROL, SULFATE ION | | 著者 | Azarkan, M, Charlier, P, Herman, R, Delbrassine, F, Sauvage, E, M Rabet, N, Calvo Esposito, R, Kerff, F. | | 登録日 | 2020-02-26 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structures of the free and inhibitors-bound forms of bromelain and ananain from Ananas comosus stem and in vitro study of their cytotoxicity.
Sci Rep, 10, 2020
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1W79
 | | Crystal structure of the DD-transpeptidase-carboxypeptidase from Actinomadura R39 | | 分子名称: | D-alanyl-D-alanine carboxypeptidase, MAGNESIUM ION, SULFATE ION | | 著者 | Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P. | | 登録日 | 2004-08-31 | | 公開日 | 2005-06-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins.
J. Biol. Chem., 280, 2005
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1W8Y
 | | Crystal structure of the nitrocefin acyl-DD-peptidase from Actinomadura R39. | | 分子名称: | (2R)-2-{(1R)-2-OXO-1-[(2-THIENYLACETYL)AMINO]ETHYL}-5,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC ACID, D-alanyl-D-alanine carboxypeptidase, MAGNESIUM ION, ... | | 著者 | Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P. | | 登録日 | 2004-10-01 | | 公開日 | 2005-06-28 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of the Actinomadura R39 Dd- Peptidase Reveals New Domains in Penicillin- Binding Proteins.
J.Biol.Chem., 280, 2005
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3D30
 | | Structure of an expansin like protein from Bacillus Subtilis at 1.9A resolution | | 分子名称: | Expansin like protein, FORMIC ACID, GLYCEROL | | 著者 | Kerff, F, Petrella, S, Herman, R, Sauvage, E, Joris, B, Charlier, P. | | 登録日 | 2008-05-09 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure and activity of Bacillus subtilis YoaJ (EXLX1), a bacterial expansin that promotes root colonization.
Proc.Natl.Acad.Sci.USA, 105, 2008
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1W8Q
 | | Crystal Structure of the DD-Transpeptidase-carboxypeptidase from Actinomadura R39 | | 分子名称: | COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, SULFATE ION | | 著者 | Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P. | | 登録日 | 2004-09-24 | | 公開日 | 2005-06-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal Structure of the Actinomadura R39 Dd-Peptidase Reveals New Domains in Penicillin-Binding Proteins.
J.Biol.Chem., 280, 2005
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5LWF
 | | Structure of a single domain camelid antibody fragment cAb-G10S in complex with the BlaP beta-lactamase from Bacillus licheniformis | | 分子名称: | ACETATE ION, Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-G10S | | 著者 | Vettore, N, Kerff, F, Pain, C, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | | 登録日 | 2016-09-16 | | 公開日 | 2017-11-15 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To Be Published
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1BSG
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1W7G
 | | Alpha-thrombin complex with sulfated hirudin (residues 54-65) and L- Arginine template inhibitor CS107 | | 分子名称: | HIRUDIN I, N-{(1S)-1-{[4-(3-AMINOPROPYL)PIPERAZIN-1-YL]CARBONYL}-4-[(DIAMINOMETHYLENE)AMINO]BUTYL}-3-(TRIFLUOROMETHYL)BENZENESULFONAMIDE, THROMBIN | | 著者 | Remiche, J, Sauvage, E, Herman, R, Charlier, P. | | 登録日 | 2004-09-02 | | 公開日 | 2006-05-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Design, Synthesis and Evaluation of Graftable Thrombin Inhibitors for the Preparation of Blood-Compatible Polymer Materials.
Org.Biomol.Chem., 3, 2005
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2WKH
 | | Crystal structure of the acyl-enzyme OXA-10 K70C-Ampicillin at pH 7 | | 分子名称: | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, BETA-LACTAMASE OXA-10, SULFATE ION | | 著者 | Vercheval, L, Bauvois, C, Kerff, F, Sauvage, E, Guiet, R, Charlier, P, Galleni, M. | | 登録日 | 2009-06-11 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.791 Å) | | 主引用文献 | Three Factors that Modulate the Activity of Class D Beta-Lactamases and Interfere with the Post-Translational Carboxylation of Lys70.
Biochem.J., 432, 2010
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2WUQ
 | | Crystal structure of BlaB protein from Streptomyces cacaoi | | 分子名称: | BETA-LACTAMASE REGULATORY PROTEIN BLAB, GLYCEROL | | 著者 | Dandois, S, Herman, R, Sauvage, E, Charlier, P, Joris, B, Kerff, F. | | 登録日 | 2009-10-07 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Crystal Structure of Blab Protein from Streptomyces Cacaoi
To be Published
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2WGI
 | | Crystal structure of the acyl-enzyme OXA-10 W154A-benzylpenicillin at pH 6 | | 分子名称: | BETA-LACTAMASE OXA-10, GLYCEROL, OPEN FORM - PENICILLIN G | | 著者 | Vercheval, L, Falzone, C, Sauvage, E, Herman, R, Charlier, P, Galleni, M, Kerff, F. | | 登録日 | 2009-04-20 | | 公開日 | 2009-11-10 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Critical Role of Tryptophan 154 for the Activity and Stability of Class D Beta-Lactamases.
Biochemistry, 48, 2009
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2WKX
 | | Crystal structure of the native E. coli zinc amidase AmiD | | 分子名称: | CHLORIDE ION, GLYCEROL, N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMID, ... | | 著者 | Petrella, S, Kerff, F, Herman, R, Genereux, C, Pennartz, A, Sauvage, E, Joris, B, Charlier, P. | | 登録日 | 2009-06-18 | | 公開日 | 2010-01-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Specific Structural Features of the N-Acetylmuramoyl-L-Alanine Amidase Amid from Escherichia Coli and Mechanistic Implications for Enzymes of This Family.
J.Mol.Biol., 397, 2010
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2X02
 | | CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 AT 1.35 A RESOLUTION | | 分子名称: | BETA-LACTAMASE OXA-10, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Vercheval, L, Kerff, F, Sauvage, E, Herman, R, Galleni, M, Charlier, P. | | 登録日 | 2009-12-04 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Impact of the Carboxylated Lysine on the Acylation and Deacylation Step in Class D Beta-Lactamase
To be Published
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2X71
 | | Structural basis for the interaction of lactivicins with serine beta- lactamases | | 分子名称: | (2E)-2-{[(2S)-2-(ACETYLAMINO)-2-CARBOXYETHOXY]IMINO}PENTANEDIOIC ACID, BETA-LACTAMASE, ETHANOL, ... | | 著者 | Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | | 登録日 | 2010-02-22 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis for the Interaction of Lactivicins with Serine Beta-Lactamases.
J.Med.Chem., 53, 2010
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2WK0
 | | Crystal structure of the class A beta-lactamase BS3 inhibited by 6- beta-iodopenicillanate. | | 分子名称: | (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, BETA-LACTAMASE, CHLORIDE ION, ... | | 著者 | Sauvage, E, Zervosen, A, Dive, G, Herman, R, Kerff, F, Amoroso, A, Fonze, E, Pratt, R.F, Luxen, A, Charlier, P. | | 登録日 | 2009-06-03 | | 公開日 | 2009-12-01 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate.
J.Am.Chem.Soc., 131, 2009
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8A0D
 | | Crystal structure of the major guinea pig allergen Cav p 1.0101 part of the lipocalin family | | 分子名称: | Allergen lipocalin Cav p 1 isoform 1 | | 著者 | Herman, R, Charlier, P, Janssen-Weets, B, Hilger, C, Swiontek, K. | | 登録日 | 2022-05-27 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.685 Å) | | 主引用文献 | Mammalian derived lipocalin and secretoglobin respiratory allergens strongly bind ligands with potentially immune modulating properties.
Front Allergy, 3, 2022
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2XK1
 | | Crystal structure of a complex between Actinomadura R39 DD-peptidase and a boronate inhibitor | | 分子名称: | COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, SULFATE ION, ... | | 著者 | Sauvage, E, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | | 登録日 | 2010-07-07 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors
Acs Med.Chem.Lett., 2, 2011
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2WKE
 | | Crystal structure of the Actinomadura R39 DD-peptidase inhibited by 6- beta-iodopenicillanate. | | 分子名称: | (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, ... | | 著者 | Sauvage, E, Herman, R, Kerff, F, Charlier, P. | | 登録日 | 2009-06-10 | | 公開日 | 2009-12-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate.
J.Am.Chem.Soc., 131, 2009
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2WKI
 | | Crystal structure of the OXA-10 K70C mutant at pH 7.0 | | 分子名称: | 1,2-ETHANEDIOL, BETA-LACTAMASE OXA-10, GLYCEROL, ... | | 著者 | Vercheval, L, Bauvois, C, Kerff, F, Sauvage, E, Guiet, R, Charlier, P, Galleni, M. | | 登録日 | 2009-06-11 | | 公開日 | 2010-08-25 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Three Factors that Modulate the Activity of Class D Beta-Lactamases and Interfere with the Post-Translational Carboxylation of Lys70.
Biochem.J., 432, 2010
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