6Y6L

Structure the ananain protease from Ananas comosus with a thiomethylated catalytic cysteine

Summary for 6Y6L

Entry DOI	10.2210/pdb6y6l/pdb
Related	6YCB 6YCC 6YCD 6YCE 6YCF 6YCG
Descriptor	Ananain, SULFATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	cysteine protease, stem bromelain protein, hydrolase
Biological source	Ananas comosus (Pineapple)
Total number of polymer chains	2
Total formula weight	48126.27
Authors	Azarkan, M.,Charlier, P.,Herman, R.,Delbrassine, F.,Sauvage, E.,M Rabet, N.,Calvo Esposito, R.,Kerff, F. (deposition date: 2020-02-26, release date: 2020-11-25, Last modification date: 2024-01-24)
Primary citation	Azarkan, M.,Maquoi, E.,Delbrassine, F.,Herman, R.,M'Rabet, N.,Calvo Esposito, R.,Charlier, P.,Kerff, F. Structures of the free and inhibitors-bound forms of bromelain and ananain from Ananas comosus stem and in vitro study of their cytotoxicity. Sci Rep, 10:19570-19570, 2020 Cited by PubMed: 33177555 DOI: 10.1038/s41598-020-76172-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation