6YCF
Structure the bromelain protease from Ananas comosus in complex with the E64 inhibitor
Summary for 6YCF
Entry DOI | 10.2210/pdb6ycf/pdb |
Related | 6Y6L |
Descriptor | FBSB, alpha-D-xylopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, ... (7 entities in total) |
Functional Keywords | cysteine protease, stem bromelain protein, hydrolase |
Biological source | Ananas comosus (Pineapple) |
Total number of polymer chains | 2 |
Total formula weight | 48855.91 |
Authors | Azarkan, M.,Charlier, P.,Herman, R.,Delbrassine, F.,Sauvage, E.,M Rabet, N.,Calvo Esposito, R.,Kerff, F. (deposition date: 2020-03-18, release date: 2020-11-25, Last modification date: 2024-10-09) |
Primary citation | Azarkan, M.,Maquoi, E.,Delbrassine, F.,Herman, R.,M'Rabet, N.,Calvo Esposito, R.,Charlier, P.,Kerff, F. Structures of the free and inhibitors-bound forms of bromelain and ananain from Ananas comosus stem and in vitro study of their cytotoxicity. Sci Rep, 10:19570-19570, 2020 Cited by PubMed: 33177555DOI: 10.1038/s41598-020-76172-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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