7XVL
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![BU of 7xvl by Molmil](/molmil-images/mine/7xvl) | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169an DNA fragment) | 分子名称: | DNA (169-MER), Histone H1.0, Histone H2A type 1-B/E, ... | 著者 | Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A. | 登録日 | 2022-05-24 | 公開日 | 2023-05-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.506 Å) | 主引用文献 | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169an DNA fragment) To Be Published
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1Q1Q
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![BU of 1q1q by Molmil](/molmil-images/mine/1q1q) | Crystal structure of human pregnenolone sulfotransferase (SULT2B1a) in the presence of PAP | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ADENOSINE-3'-5'-DIPHOSPHATE, SODIUM ION, ... | 著者 | Lee, K.A, Fuda, H, Lee, Y.C, Negishi, M, Strott, C.A, Pedersen, L.C. | 登録日 | 2003-07-22 | 公開日 | 2003-11-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone
and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical
SULT2A1 and the SULT2BG1 isoforms. J.Biol.Chem., 278, 2003
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7XX5
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![BU of 7xx5 by Molmil](/molmil-images/mine/7xx5) | Crystal Structure of Nucleosome-H1.3 Linker Histone Assembly (sticky-169a DNA fragment) | 分子名称: | CALCIUM ION, DNA (169-MER), Histone H1.3, ... | 著者 | Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A. | 登録日 | 2022-05-28 | 公開日 | 2023-05-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment) To Be Published
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3EWF
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![BU of 3ewf by Molmil](/molmil-images/mine/3ewf) | Crystal Structure Analysis of human HDAC8 H143A variant complexed with substrate. | 分子名称: | 7-AMINO-4-METHYL-CHROMEN-2-ONE, Histone deacetylase 8, PEPTIDIC SUBSTRATE, ... | 著者 | Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2008-10-14 | 公開日 | 2008-12-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry, 47, 2008
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3EYO
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![BU of 3eyo by Molmil](/molmil-images/mine/3eyo) | Crystal structure of anti-human cytomegalovirus antibody 8F9 | 分子名称: | 8f9 Fab, AD-2 | 著者 | Thomson, C.A, Bryson, S, McLean, G.R, Creagh, A.L, Pai, E.F, Schrader, J.W. | 登録日 | 2008-10-21 | 公開日 | 2008-12-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus. Embo J., 27, 2008
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3F06
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![BU of 3f06 by Molmil](/molmil-images/mine/3f06) | Crystal Structure Analysis of Human HDAC8 D101A Variant. | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, BETA-MERCAPTOETHANOL, Histone deacetylase 8, ... | 著者 | Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. | 登録日 | 2008-10-24 | 公開日 | 2008-12-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry, 47, 2008
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3F12
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![BU of 3f12 by Molmil](/molmil-images/mine/3f12) | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus | 分子名称: | 8f9 Fab, M2J1 Fab | 著者 | Thomson, C.A, Bryson, S, McLean, G.R, Creagh, A.L, Pai, E.F, Schrader, J.W. | 登録日 | 2008-10-27 | 公開日 | 2009-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus. Embo J., 27, 2008
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4F74
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![BU of 4f74 by Molmil](/molmil-images/mine/4f74) | |
3G5T
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![BU of 3g5t by Molmil](/molmil-images/mine/3g5t) | Crystal structure of trans-aconitate 3-methyltransferase from yeast | 分子名称: | (2E)-2-(2-methoxy-2-oxoethyl)but-2-enedioic acid, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | 著者 | Burgie, E.S, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2009-02-05 | 公開日 | 2009-03-03 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.119 Å) | 主引用文献 | Crystal structure of trans-aconitate 3-methyltransferase from yeast To be Published
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4FE3
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![BU of 4fe3 by Molmil](/molmil-images/mine/4fe3) | |
4EYM
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![BU of 4eym by Molmil](/molmil-images/mine/4eym) | MAPK13 complex with inhibitor | 分子名称: | 2-(morpholin-4-yl)-N-[4-(pyridin-4-yloxy)phenyl]pyridine-4-carboxamide, Mitogen-activated protein kinase 13 | 著者 | Miller, C.A, Brett, T.J. | 登録日 | 2012-05-01 | 公開日 | 2012-12-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.353 Å) | 主引用文献 | IL-13-induced airway mucus production is attenuated by MAPK13 inhibition. J.Clin.Invest., 122, 2012
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1NA2
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![BU of 1na2 by Molmil](/molmil-images/mine/1na2) | |
3GEN
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![BU of 3gen by Molmil](/molmil-images/mine/3gen) | The 1.6 A crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound | 分子名称: | 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane, Tyrosine-protein kinase BTK | 著者 | Marcotte, D.J, Liu, Y.T, Arduini, R.M, Hession, C.A, Miatkowski, K, Wildes, C.P, Cullen, P.F, Hopkins, B, Mertsching, E, Jenkins, T.J, Romanowski, M.J, Baker, D.P, Silvian, L.F. | 登録日 | 2009-02-25 | 公開日 | 2010-01-19 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases. Protein Sci., 19, 2010
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4D41
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![BU of 4d41 by Molmil](/molmil-images/mine/4d41) | Crystal structure of S. aureus FabI in complex with NADP and 5-hexyl- 2-(4-nitrophenoxy)phenol | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 5-HEXYL-2-(4-NITROPHENOXY)PHENOL, ... | 著者 | Schiebel, J, Chang, A, Tonge, P.J, Sotriffer, C.A, Kisker, C. | 登録日 | 2014-10-26 | 公開日 | 2015-03-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | An Ordered Water Channel in Staphylococcus Aureus Fabi: Unraveling the Mechanism of Substrate Recognition and Reduction. Biochemistry, 54, 2015
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4D46
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![BU of 4d46 by Molmil](/molmil-images/mine/4d46) | Crystal structure of E. coli FabI in complex with NAD and 5-bromo-2-(4-chloro-2-hydroxyphenoxy)benzonitrile | 分子名称: | 5-bromo-2-(4-chloro-2-hydroxyphenoxy)benzonitrile, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Tareilus, M, Schiebel, J, Chang, A, Tonge, P.J, Sotriffer, C.A, Kisker, C. | 登録日 | 2014-10-26 | 公開日 | 2015-03-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | An Ordered Water Channel in Staphylococcus Aureus Fabi: Unraveling the Mechanism of Substrate Recognition and Reduction. Biochemistry, 54, 2015
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3GAN
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![BU of 3gan by Molmil](/molmil-images/mine/3gan) | Crystal structure of gene product from Arabidopsis thaliana At3g22680 with bound suramin | 分子名称: | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, CHLORIDE ION, Uncharacterized protein At3g22680 | 著者 | Burgie, E.S, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2009-02-17 | 公開日 | 2009-03-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of gene product from Arabidopsis thaliana At3g22680 with bound suramin To be Published
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1NLJ
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![BU of 1nlj by Molmil](/molmil-images/mine/1nlj) | |
3FCH
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4D45
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![BU of 4d45 by Molmil](/molmil-images/mine/4d45) | Crystal structure of S. aureus FabI in complex with NADP and 5-bromo- 2-(4-chloro-2-hydroxyphenoxy)benzonitrile | 分子名称: | 5-bromo-2-(4-chloro-2-hydroxyphenoxy)benzonitrile, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | 著者 | Tareilus, M, Schiebel, J, Chang, A, Tonge, P.J, Sotriffer, C.A, Kisker, C. | 登録日 | 2014-10-26 | 公開日 | 2015-03-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | An Ordered Water Channel in Staphylococcus Aureus Fabi: Unraveling the Mechanism of Substrate Recognition and Reduction. Biochemistry, 54, 2015
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3GI4
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![BU of 3gi4 by Molmil](/molmil-images/mine/3gi4) | Crystal structure of protease inhibitor, KB60 in complex with wild type HIV-1 protease | 分子名称: | 5S)-N-[(1S,2R)-3-[(1,3-Benzodioxol-5-ylsulfonyl)(2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-2-oxo-3-[3-(tr ifluoromethyl)phenyl]-5-oxazolidinecarboxamide, ACETATE ION, PHOSPHATE ION, ... | 著者 | Nalam, M.N.L, Schiffer, C.A. | 登録日 | 2009-03-05 | 公開日 | 2010-03-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Evaluating the substrate-envelope hypothesis: structural analysis of novel HIV-1 protease inhibitors designed to be robust against drug resistance. J.Virol., 84, 2010
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1QGU
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![BU of 1qgu by Molmil](/molmil-images/mine/1qgu) | NITROGENASE MO-FE PROTEIN FROM KLEBSIELLA PNEUMONIAE, DITHIONITE-REDUCED STATE | 分子名称: | 1,2-ETHANEDIOL, 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CHLORIDE ION, ... | 著者 | Mayer, S.M, Lawson, D.M, Gormal, C.A, Roe, S.M, Smith, B.E. | 登録日 | 1999-05-06 | 公開日 | 1999-11-01 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | New insights into structure-function relationships in nitrogenase: A 1.6 A resolution X-ray crystallographic study of Klebsiella pneumoniae MoFe-protein. J.Mol.Biol., 292, 1999
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1QRJ
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![BU of 1qrj by Molmil](/molmil-images/mine/1qrj) | Solution structure of htlv-i capsid protein | 分子名称: | HTLV-I CAPSID PROTEIN | 著者 | Khorasanizadeh, S, Campos-Olivas, R, Clark, C.A, Summers, M.F. | 登録日 | 1999-06-14 | 公開日 | 1999-07-13 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Sequence-specific 1H, 13C and 15N chemical shift assignment and secondary structure of the HTLV-I capsid protein. J.Biomol.NMR, 14, 1999
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4EYJ
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![BU of 4eyj by Molmil](/molmil-images/mine/4eyj) | MAPK13 Complex with inhibitor | 分子名称: | 1-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-3-[4-(pyridin-4-yloxy)phenyl]urea, Mitogen-activated protein kinase 13 | 著者 | Miller, C.A, Brett, T.J. | 登録日 | 2012-05-01 | 公開日 | 2012-12-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | IL-13-induced airway mucus production is attenuated by MAPK13 inhibition. J.Clin.Invest., 122, 2012
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4F4J
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![BU of 4f4j by Molmil](/molmil-images/mine/4f4j) | Conversion of the enzyme guanylate kinase into a mitotic spindle orienting protein by a single mutation that inhibits gmp- induced closing | 分子名称: | Guanylate kinase, SULFATE ION | 著者 | Johnston, C.A, Whitney, D, Volkman, B.F, Prehoda, K.E. | 登録日 | 2012-05-10 | 公開日 | 2012-06-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Conversion of the enzyme guanylate kinase into a mitotic-spindle orienting protein by a single mutation that inhibits GMP-induced closing. Proc.Natl.Acad.Sci.USA, 108, 2011
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4F73
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