Crystal structure of human pregnenolone sulfotransferase (SULT2B1a) in the presence of PAP

Summary for 1Q1Q

Related1Q1Z 1Q20 1Q22
Descriptorsulfotransferase family, cytosolic, 2B, member 1 isoform a, SODIUM ION, ADENOSINE-3'-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywordssulfotransferase, pregnenolone, sult2b1, pap, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm O00204
Total number of polymer chains1
Total molecular weight40510.64
Lee, K.A.,Fuda, H.,Lee, Y.C.,Negishi, M.,Strott, C.A.,Pedersen, L.C. (deposition date: 2003-07-22, release date: 2003-11-11, Last modification date: 2017-10-11)
Primary citation
Lee, K.A.,Fuda, H.,Lee, Y.C.,Negishi, M.,Strott, C.A.,Pedersen, L.C.
Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical SULT2A1 and the SULT2BG1 isoforms.
J.Biol.Chem., 278:44593-44599, 2003
PubMed: 12923182 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M308312200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.276314.0%3.1%1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-07-29