4F73

Crystal Structure of active HIV-1 Protease in Complex with the N terminal product of CA-p2 cleavage site

Summary for 4F73

• Entry DOI: 10.2210/pdb4f73/pdb
• Related: 4F74 4F75 4F76
• Descriptor: Protease, N terminal product of substrate CA-p2, ACETATE ION, ... (5 entities in total)
• Functional Keywords: hiv-1 protease, substrate complex, aids, product complex, aspartyl protease, hydrolase, hydrolase-hydrolase product complex, hydrolase/hydrolase product
• Biological source: HIV-1 M:B_ARV2/SF2 (HIV-1); More
• Cellular location: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03369
• Total number of polymer chains: 4
• Total formula weight: 22930.17

Authors

Schiffer, C.A.,Mittal, S.,Nalam, M.N.L. (deposition date: 2012-05-15, release date: 2013-05-15, Last modification date: 2024-02-28)

• Primary citation: Mittal, S.,Nalam, M.N.L.,Schiffer, C.A.; Crystal Structure of active HIV-1 Protease in Complex with the N terminal product of CA-p2 cleavage site; To be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)