4F73
Crystal Structure of active HIV-1 Protease in Complex with the N terminal product of CA-p2 cleavage site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 99 | 10801.8 | 2 | UniProt (P03369) Pfam (PF00077) | HIV-1 M:B_ARV2/SF2 (HIV-1) | |
| 2 | C, D (C, D) | N terminal product of substrate CA-p2 | polymer | 5 | 587.8 | 2 | Human immunodeficiency virus 1 | ||
| 3 | E (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P03369)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 497 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 22779.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 151.1 | |
| All* | Total formula weight | 22930.2 |
