4F74
Crystal Structure of active HIV-1 Protease in Complex with the N terminal product of the substrate MA-CA.
Summary for 4F74
Entry DOI | 10.2210/pdb4f74/pdb |
Related | 4F73 4F75 4F76 |
Descriptor | Protease, N terminal product of substrate MA-CA (3 entities in total) |
Functional Keywords | hiv-1 protease, substrate complex, aids, product complex, aspartyl protease, hydrolase, hydrolase-hydrolase product complex, hydrolase/hydrolase product |
Biological source | HIV-1 M:B_ARV2/SF2 (HIV-1) More |
Cellular location | Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03369 |
Total number of polymer chains | 3 |
Total formula weight | 22213.16 |
Authors | Schiffer, C.A.,Mittal, S.,Nalam, M.N.L. (deposition date: 2012-05-15, release date: 2013-05-15, Last modification date: 2024-02-28) |
Primary citation | Mittal, S.,Nalam, M.N.L.,Schiffer, C.A. Crystal Structure of active HIV-1 Protease in Complex with the N terminal product of the substrate MA-CA. To be Published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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