4EYM
MAPK13 complex with inhibitor
Summary for 4EYM
| Entry DOI | 10.2210/pdb4eym/pdb |
| Related | 4EXU 4EYJ |
| Descriptor | Mitogen-activated protein kinase 13, 2-(morpholin-4-yl)-N-[4-(pyridin-4-yloxy)phenyl]pyridine-4-carboxamide (3 entities in total) |
| Functional Keywords | p38 family kinase, map kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 43010.31 |
| Authors | Miller, C.A.,Brett, T.J. (deposition date: 2012-05-01, release date: 2012-12-19, Last modification date: 2024-02-28) |
| Primary citation | Alevy, Y.G.,Patel, A.C.,Romero, A.G.,Patel, D.A.,Tucker, J.,Roswit, W.T.,Miller, C.A.,Heier, R.F.,Byers, D.E.,Brett, T.J.,Holtzman, M.J. IL-13-induced airway mucus production is attenuated by MAPK13 inhibition. J.Clin.Invest., 122:4555-4568, 2012 Cited by PubMed: 23187130DOI: 10.1172/JCI64896 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.353 Å) |
Structure validation
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