7N0A
 
 | | Structure of Human Leukaemia Inhibitory Factor with Fab MSC1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Leukemia inhibitory factor, ... | | Authors: | Raman, S, Bosch, A, Fransson, J, Julien, J.P. | | Deposit date: | 2021-05-25 | | Release date: | 2022-06-15 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment.
Clin.Cancer Res., 29, 2023
|
|
5BK0
 | | Crystal structure of 663 Fab bound to circumsporozoite protein NANP 5-mer | | Descriptor: | 663 Antibody, heavy chain, light chain, ... | | Authors: | Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | | Deposit date: | 2017-09-12 | | Release date: | 2017-12-13 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.
Immunity, 47, 2017
|
|
5BK3
 | | Crystal structure of the neutralizing anti-circumsporozoite protein 580 antibody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 580 Antibody, heavy chain, ... | | Authors: | Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | | Deposit date: | 2017-09-12 | | Release date: | 2017-12-13 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.
Immunity, 47, 2017
|
|
5BK5
 | | Crystal structure of the anti-circumsporozoite protein 663 germline antibody | | Descriptor: | 663 germline antibody, heavy chain, light chain, ... | | Authors: | Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | | Deposit date: | 2017-09-12 | | Release date: | 2017-12-13 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.
Immunity, 47, 2017
|
|
6B0W
 | | Crystal structure of the anti-circumsporozoite protein 1710 antibody | | Descriptor: | 1710 antibody, heavy chain, light chain, ... | | Authors: | Scally, S.W, Murugan, R, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | | Deposit date: | 2017-09-15 | | Release date: | 2017-11-08 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.
J. Exp. Med., 215, 2018
|
|
6B0S
 | | Crystal structure of circumsporozoite protein aTSR domain in complex with 1710 antibody | | Descriptor: | 1710 antibody, heavy chain, light chain, ... | | Authors: | Scally, S.W, Murugan, R, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | | Deposit date: | 2017-09-15 | | Release date: | 2017-11-08 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.
J. Exp. Med., 215, 2018
|
|
6B0G
 | | Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245 | | Descriptor: | 1245 Antibody, Heavy Chain, Light Chain, ... | | Authors: | McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P. | | Deposit date: | 2017-09-14 | | Release date: | 2017-11-08 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
|
|
6AZZ
 | | Crystal structure of Pfs25 in complex with the transmission blocking antibody 1190 | | Descriptor: | 1190 antibody, heavy chain, light chain, ... | | Authors: | Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. | | Deposit date: | 2017-09-13 | | Release date: | 2017-11-08 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
|
|
6O26
 | | Crystal structure of 3246 Fab in complex with circumsporozoite protein NANA | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3246 Fab heavy chain, ... | | Authors: | Scally, S.W, Bosch, A, Castro, K, Murugan, R, Wardemann, H, Julien, J.P. | | Deposit date: | 2019-02-22 | | Release date: | 2020-03-04 | | Last modified: | 2020-09-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
|
|
6O24
 | | Crystal structure of 4498 Fab in complex with circumsporozoite protein NANP3 and anti-Kappa VHH domain | | Descriptor: | 1,2-ETHANEDIOL, 4498 Fab heavy chain, 4498 Kappa light chain, ... | | Authors: | Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P. | | Deposit date: | 2019-02-22 | | Release date: | 2020-07-01 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
|
|
6O28
 | | Crystal structure of 4493 Fab in complex with circumsporozoite protein KQPA and anti-kappa VHH domain | | Descriptor: | 1,2-ETHANEDIOL, 4493 Fab heavy chain, 4493 Kappa light chain, ... | | Authors: | Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P. | | Deposit date: | 2019-02-22 | | Release date: | 2020-07-01 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
|
|
6O25
 | | Crystal structure of 3945 Fab in complex with circumsporozoite protein NANP3 and anti-Kappa VHH domain | | Descriptor: | 3945 Fab heavy chain, 3945 Kappa light chain, Anti-Kappa VHH domain, ... | | Authors: | Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P. | | Deposit date: | 2019-02-22 | | Release date: | 2020-07-01 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
|
|
6AZX
 | | Crystal structure of the neutralizing anti-circumsporozoite protein 663 antibody | | Descriptor: | 663 antibody, heavy chain, light chain | | Authors: | Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | | Deposit date: | 2017-09-13 | | Release date: | 2017-12-13 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.
Immunity, 47, 2017
|
|
6B0E
 | | Crystal structure of Pfs25 in complex with the transmission blocking antibody 1260 | | Descriptor: | 1260 antibody, heavy chain, light chain, ... | | Authors: | Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. | | Deposit date: | 2017-09-14 | | Release date: | 2017-11-15 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
|
|
6O2C
 | | Crystal structure of 4493 Fab in complex with circumsporozoite protein NANP3 and anti-kappa VHH domain | | Descriptor: | 1,2-ETHANEDIOL, 4493 Fab heavy chain, 4493 Kappa light chain, ... | | Authors: | Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P. | | Deposit date: | 2019-02-22 | | Release date: | 2020-07-01 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.017 Å) | | Cite: | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
|
|
6O2A
 | | Crystal structure of 4493 Fab in complex with circumsporozoite protein NDN and anti-kappa VHH domain | | Descriptor: | 1,2-ETHANEDIOL, 4493 Fab heavy chain, 4493 Kappa light chain, ... | | Authors: | Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P. | | Deposit date: | 2019-02-22 | | Release date: | 2020-07-01 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
|
|
6O2B
 | | Crystal structure of 4493 Fab in complex with circumsporozoite protein DND and anti-kappa VHH domain | | Descriptor: | 1,2-ETHANEDIOL, 4493 Fab heavy chain, 4493 Kappa light chain, ... | | Authors: | Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P. | | Deposit date: | 2019-02-22 | | Release date: | 2020-07-01 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
|
|
6O23
 | | Crystal structure of 2243 Fab in complex with circumsporozoite protein NANP5 | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2243 Fab heavy chain, ... | | Authors: | Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P. | | Deposit date: | 2019-02-22 | | Release date: | 2020-03-04 | | Last modified: | 2020-09-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
|
|
6O29
 | | Crystal structure of 4493 Fab in complex with circumsporozoite protein NPDP and anti-kappa VHH domain | | Descriptor: | 1,2-ETHANEDIOL, 4493 Fab heavy chain, 4493 Kappa light chain, ... | | Authors: | Scally, S.W, Bosch, A, Prieto, K, Murugan, R, Wardemann, H, Julien, J.P. | | Deposit date: | 2019-02-22 | | Release date: | 2020-07-01 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.
Nat. Med., 26, 2020
|
|
6AZM
 | | Crystal structure of the 580 germline antibody bound to circumsporozoite protein NANP 5-mer | | Descriptor: | 580 germline antibody, heavy chain, light chain, ... | | Authors: | Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | | Deposit date: | 2017-09-11 | | Release date: | 2017-12-13 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.
Immunity, 47, 2017
|
|
6D11
 | | Crystal structure of 1450 Fab in complex with circumsporozoite protein NANP5 | | Descriptor: | 1450 Antibody, Heavy chain, Light chain, ... | | Authors: | Scally, S.W, Bosch, A, Imkeller, K, Wardemann, H, Julien, J.P. | | Deposit date: | 2018-04-11 | | Release date: | 2018-06-13 | | Last modified: | 2018-07-04 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope.
Science, 360, 2018
|
|
6B0A
 | | Crystal structure of Pfs25 in complex with the transmission blocking antibody 1269 | | Descriptor: | 1269 antibody, heavy chain, light chain, ... | | Authors: | Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. | | Deposit date: | 2017-09-14 | | Release date: | 2017-11-15 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
|
|
6B08
 | | Crystal structure of Pfs25 in complex with the transmission blocking antibody 1276 | | Descriptor: | 1276 antibody, heavy chain, light chain, ... | | Authors: | Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. | | Deposit date: | 2017-09-14 | | Release date: | 2017-11-15 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
|
|
6B0H
 | | Crystal structure of Pfs25 in complex with the transmission blocking antibody 1262 | | Descriptor: | 1,2-ETHANEDIOL, 1262 antibody, heavy chain, ... | | Authors: | McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P. | | Deposit date: | 2017-09-14 | | Release date: | 2017-11-15 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
|
|
6D0X
 | | Crystal structure of chimeric H.2140 / K.1210 Fab in complex with circumsporozoite protein NANP3 | | Descriptor: | 1210 Antibody, light chain, 2140 Antibody, ... | | Authors: | Scally, S.W, Bosch, A, Imkeller, K, Wardemann, H, Julien, J.P. | | Deposit date: | 2018-04-11 | | Release date: | 2018-06-13 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.849 Å) | | Cite: | Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope.
Science, 360, 2018
|
|
