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PDB: 37 件
1AEY
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ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, SOLUTION NMR, 15 STRUCTURES
分子名称: ALPHA-SPECTRIN
著者Blanco, F.J, Ortiz, A.R, Serrano, L.
登録日1997-03-02
公開日1997-05-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献1H and 15N NMR assignment and solution structure of the SH3 domain of spectrin: comparison of unrefined and refined structure sets with the crystal structure.
J.Biomol.NMR, 9, 1997
2M1R
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BU of 2m1r by Molmil
PHD domain of ING4 N214D mutant
分子名称: Inhibitor of growth protein 4, ZINC ION
著者Blanco, F.J.
登録日2012-12-05
公開日2012-12-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Functional impact of cancer-associated mutations in the tumor suppressor protein ING4.
Carcinogenesis, 31, 2010
1PU1
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BU of 1pu1 by Molmil
Solution structure of the Hypothetical protein mth677 from Methanothermobacter Thermautotrophicus
分子名称: Hypothetical protein MTH677
著者Blanco, F.J, Yee, A, Campos-Olivas, R, Devos, D, Valencia, A, Arrowsmith, C.H, Rico, M.
登録日2003-06-23
公開日2004-06-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the hypothetical protein Mth677 from Methanobacterium thermoautotrophicum: A novel {alpha}+{beta} fold
Protein Sci., 13, 2004
6EHT
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BU of 6eht by Molmil
Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme
分子名称: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), PCNA-associated factor, ...
著者De March, M, Barrera-Vilarmau, S, Mentegari, E, Merino, N, Bressan, E, Maga, G, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A.
登録日2017-09-15
公開日2018-08-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
8COK
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BU of 8cok by Molmil
Structural analysis of ING3 protein and its binding to histone H3
分子名称: Inhibitor of growth protein 3
著者Ferreras-Gutierrez, M, Medrano, F.J, Blanco, F.J.
登録日2023-02-28
公開日2023-05-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Structural analysis of ING3 protein and histone H3 binding.
Int.J.Biol.Macromol., 242, 2023
8OY1
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BU of 8oy1 by Molmil
Structure of the human Guanine Nucleotide-Binding Protein G(K) Subunit Alpha
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-3
著者Medrano, F.J, Blanco, F.J, Ferreras-Gutierrez, M.O.
登録日2023-05-03
公開日2024-05-15
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Structure of the human Guanine Nucleotide-Binding Protein G(K) Subunit Alpha
To Be Published
2XE0
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BU of 2xe0 by Molmil
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
分子名称: 24MER DNA, ACETATE ION, I-CREI V2V3 VARIANT, ...
著者Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Redondo, P, Villate, M, Merino, N, Marenchino, M, D'Abramo, M, Gervasio, F.L, Grizot, S, Daboussi, F, Smith, J, Chion-Sotine, I, Paques, F, Duchateau, P, Alibes, A, Stricher, F, Serrano, L, Blanco, F.J, Montoya, G.
登録日2010-05-10
公開日2010-09-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Molecular Basis of Engineered Meganuclease Targeting of the Endogenous Human Rag1 Locus
Nucleic Acids Res., 39, 2011
6HVO
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BU of 6hvo by Molmil
Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase delta
分子名称: DNA polymerase delta subunit 4, Proliferating cell nuclear antigen, SULFATE ION
著者Gonzalez-Magana, A, Romano-Moreno, M, Rojas, A.L, Blanco, F.J, De Biasio, A.
登録日2018-10-11
公開日2019-01-23
最終更新日2019-03-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The p12 subunit of human polymerase delta uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA).
J.Biol.Chem., 294, 2019
7ZMX
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BU of 7zmx by Molmil
Crystal structure of the Plant Homeodomain (PHD) of human ING3
分子名称: CALCIUM ION, Inhibitor of growth protein 3, ZINC ION
著者Ferreras, M.O, Medrano, F.J, Blanco, F.J.
登録日2022-04-20
公開日2023-05-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural analysis of ING3 protein and histone H3 binding.
Int.J.Biol.Macromol., 242, 2023
5ME8
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N-terminal domain of the human tumor suppressor ING5
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, Inhibitor of growth protein 5
著者Roversi, P, Blanco, F.J, Rojas, A.L, Buitrago, J.A.R.
登録日2016-11-14
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.
J.Mol.Biol., 431, 2019
5MTO
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BU of 5mto by Molmil
N-terminal domain of the human tumor suppressor ING5 C19S mutant
分子名称: Inhibitor of growth protein 5, SODIUM ION, SULFATE ION
著者Ormaza, G, Buitrago, J.A.R, Roversi, P, Rojas, A.L, Blanco, F.J.
登録日2017-01-10
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.
J.Mol.Biol., 431, 2019
6GIS
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BU of 6gis by Molmil
Structural basis of human clamp sliding on DNA
分子名称: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), Proliferating cell nuclear antigen
著者De March, M, Merino, N, Barrera-Vilarmau, S, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A.
登録日2018-05-15
公開日2018-05-30
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structural basis of human PCNA sliding on DNA.
Nat Commun, 8, 2017
8P8H
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BU of 8p8h by Molmil
Crystal structure of HHD2 domain of hRTEL1
分子名称: Regulator of telomere elongation helicase 1
著者Hegde, R.P, Kanade, M, Cortone, G, Graewert, M, Longo, A, Gonzalez, A, Chaves-Arquero, B, Blanco, F.J, Napolitano, L.M.R, Onesti, S.
登録日2023-06-01
公開日2024-06-12
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of HHD2 domain of hRTEL1
To Be Published
6G52
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BU of 6g52 by Molmil
CRYSTAL STRUCTURE OF THE CNMP BINDING DOMAIN OF THE MAGNESIUM TRANSPORTER CNNM4
分子名称: Metal transporter CNNM4
著者Gimenez, P, Oyenarte, I, Hardy, S, Zubillaga, M, Merino, N, Blanco, F.J, Siliqi, D, Tremblay, M, Muller, D, Martinez-Cruz, L.A.
登録日2018-03-28
公開日2019-04-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.691 Å)
主引用文献Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4.
Int J Mol Sci, 20, 2019
4ZTD
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BU of 4ztd by Molmil
Crystal Structure of Human PCNA in complex with a TRAIP peptide
分子名称: ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen
著者Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A.
登録日2015-05-14
公開日2015-12-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.
J.Cell Biol., 212, 2016
2VBL
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BU of 2vbl by Molmil
Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers
分子名称: 5'-D(*DA*DA*DA*DA*DG*DG*DC*DA*DG*DAP)-3', 5'-D(*DA*DG*DG*DA*DT*DC*DC*DT*DA*DAP)-3', 5'-D(*DT*DC*DT*DG*DC*DC*DT*DT*DT*DT*DT*DT *DGP*DAP)-3', ...
著者Redondo, P, Prieto, J, Munoz, I.G, Alibes, A, Stricher, F, Serrano, L, Arnould, S, Perez, C, Cabaniols, J.P, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G.
登録日2007-09-14
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
2VBN
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BU of 2vbn by Molmil
Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers
分子名称: 5'-D(*AP*AP*AP*AP*GP*GP*CP*AP*GP*AP)-3', 5'-D(*AP*GP*GP*AP*TP*CP*CP*TP*AP*AP)-3', 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP)-3', ...
著者Redondo, P, Prieto, J, Munoz, I.G, Alibes, A, Stricher, F, Serrano, L, Arnould, S, Perez, C, Cabaniols, J.P, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G.
登録日2007-09-14
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
2VBJ
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BU of 2vbj by Molmil
Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers
分子名称: 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP*AP*GP*GP*AP*TP*CP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP*AP*AP*AP*AP*GP*GP*CP*AP*GP*A)-3', CALCIUM ION, ...
著者Redondo, P, Prieto, J, Munoz, I.G, Alibes, A, Stricher, F, Serrano, L, Arnould, S, Perez, C, Cabaniols, J.P, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G.
登録日2007-09-14
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
6GWS
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BU of 6gws by Molmil
Crystal structure of human PCNA in complex with three p15 peptides
分子名称: PCNA-associated factor, Proliferating cell nuclear antigen
著者De March, M, Merino, N, Gonzalez-Magana, A, Romano-Moreno, M, Onesti, S, Blanco, F.J, De Biasio, A.
登録日2018-06-25
公開日2018-08-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
2VS8
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The crystal structure of I-DmoI in complex with DNA and Mn
分子名称: 5'-D(*CP*CP*GP*GP*CP*AP*AP* GP*GP*CP)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP *CP*TP*TP*AP*C)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP *GP*TP*AP*A)-3', ...
著者Marcaida, M.J, Prieto, J, Redondo, P, Nadra, A.D, Alibes, A, Serrano, L, Grizot, S, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G.
登録日2008-04-21
公開日2008-11-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of I-Dmoi in Complex with its Target DNA Provides New Insights Into Meganuclease Engineering.
Proc.Natl.Acad.Sci.USA, 105, 2008
2VNF
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MOLECULAR BASIS OF HISTONE H3K4ME3 RECOGNITION BY ING4
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, HISTONE H3, ...
著者Palacios, A, Munoz, I.G, Pantoja-Uceda, D, Marcaida, M.J, Torres, D, Martin-Garcia, J.M, Luque, I, Montoya, G, Blanco, F.J.
登録日2008-02-04
公開日2008-04-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Molecular Basis of Histone H3K4Me3 Recognition by Ing4
J.Biol.Chem., 283, 2008
2VBO
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BU of 2vbo by Molmil
Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers
分子名称: 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP*AP*GP*GP*AP*TP*CP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP*AP*AP*AP*AP*GP*GP*CP*AP*GP*A)-3', CALCIUM ION, ...
著者Redondo, P, Prieto, J, Munoz, I.G, Alibes, A, Stricher, F, Serrano, L, Arnould, S, Perez, C, Cabaniols, J.P, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G.
登録日2007-09-14
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
2VS7
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BU of 2vs7 by Molmil
The crystal structure of I-DmoI in complex with DNA and Ca
分子名称: 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP *CP*TP*TP*AP*CP*CP*CP*GP*GP*CP*AP*AP*GP*GP*C)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP *GP*TP*AP*AP*GP*TP*TP*CP*CP*GP*GP*CP*GP*CP*G)-3', ACETATE ION, ...
著者Marcaida, M.J, Prieto, J, Redondo, P, Nadra, A.D, Alibes, A, Serrano, L, Grizot, S, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G.
登録日2008-04-21
公開日2008-11-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of I-Dmoi in Complex with its Target DNA Provides New Insights Into Meganuclease Engineering.
Proc.Natl.Acad.Sci.USA, 105, 2008
5A77
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Crystal structure of the homing endonuclease I-CvuI in complex with I- CreI target (C1221) in the presence of 2 mM Mg revealing DNA cleaved
分子名称: 10MER DNA, 5'-D(*GP*AP*CP*GP*TP*TP*TP*TP* GP*AP*DGP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3', 14MER DNA, ...
著者Molina, R, Redondo, P, LopezMendez, B, Villate, M, Merino, N, Blanco, F.J, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G.
登録日2015-07-03
公開日2015-09-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the Homing Endonuclease I-Cvui Provides a New Template for Genome Modification
J.Biol.Chem., 290, 2015
2O7M
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The C-terminal loop of the homing endonuclease I-CreI is essential for DNA binding and cleavage. Identification of a novel site for specificity engineering in the I-CreI scaffold
分子名称: DNA endonuclease I-CreI
著者Prieto, J, Redondo, P, Padro, D, Blanco, F.J, Paques, F, Montoya, G.
登録日2006-12-11
公開日2007-10-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The C-terminal loop of the homing endonuclease I-CreI is essential for site recognition, DNA binding and cleavage
Nucleic Acids Res., 35, 2007

 

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