Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers

Summary for 2VBL

Related1T9I 1U0C 1U0D 1AF5 1BP7 1G9Y 1G9Z 1MOW 1N3E 1N3F 1T9J 2VBJ 2VBN 2VBO
DescriptorDNA ENDONUCLEASE I-CREI, 5'-D(*DT*DC*DT*DG*DC*DC*DT*DT*DT*DT*DT*DT *DGP*DAP)-3', 5'-D(*DT*DT*DA*DG*DG*DA*DT*DC*DC*DT*DT*DC *DAP*DAP)-3', ... (8 entities in total)
Functional Keywordsuv-induced dna damage, cutting dna endonucleases, plastid, nuclease, hydrolase, chloroplast, endonuclease, intron homing, amel3- 4_magnesium, double strand break (dsb), homing endonucleases (hes)
Cellular locationPlastid, chloroplast P05725 2VBL
Total number of polymer chains6
Total molecular weight49829.09
Redondo, P.,Prieto, J.,Munoz, I.G.,Alibes, A.,Stricher, F.,Serrano, L.,Arnould, S.,Perez, C.,Cabaniols, J.P.,Duchateau, P.,Paques, F.,Blanco, F.J.,Montoya, G. (deposition date: 2007-09-14, release date: 2008-10-28, Last modification date: 2012-06-20)
Primary citation
Redondo, P.,Prieto, J.,Munoz, I.G.,Alibes, A.,Stricher, F.,Serrano, L.,Cabaniols, J.P.,Daboussi, F.,Arnould, S.,Perez, C.,Duchateau, P.,Paques, F.,Blanco, F.J.,Montoya, G.
Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456:107-, 2008
PubMed: 18987743 (PDB entries with the same primary citation)
DOI: 10.1038/NATURE07343
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.197170.7%6.2%4.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2vbl
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Molmil generated image of 2vbl
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Molmil generated image of 2vbl
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