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2VBL

Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers

Functional Information from GO Data
ChainGOidnamespacecontents
A0004519molecular_functionendonuclease activity
A0006314biological_processintron homing
A0009507cellular_componentchloroplast
A0042802molecular_functionidentical protein binding
A0046872molecular_functionmetal ion binding
B0004519molecular_functionendonuclease activity
B0006314biological_processintron homing
B0009507cellular_componentchloroplast
B0042802molecular_functionidentical protein binding
B0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MG C 1025
ChainResidue
AGLY19
AHOH2012
BASP20
CMG1026
EDA14
TDA15
THOH2005

site_idAC2
Number of Residues8
DetailsBINDING SITE FOR RESIDUE MG C 1026
ChainResidue
CDA14
CMG1025
EDA14
EMG1025
SDA15
TDA15
AASP20
BASP20

site_idAC3
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MG E 1025
ChainResidue
AASP20
BALA19
BHOH2023
CDA14
CMG1026
SDA15
SHOH2004

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING:
ChainResidueDetails
BALA19
BASP20

Catalytic Information from CSA
site_idMCSA1
Number of Residues2
DetailsM-CSA 233
ChainResidueDetails
BALA19metal ligand
BASP20metal ligand

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PDB entries from 2024-11-06

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