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PDB: 202 件
7R8M
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BU of 7r8m by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C032
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者DeLaitsch, A.T, Barnes, C.O, Bjorkman, P.J.
登録日2021-06-26
公開日2021-08-04
最終更新日2021-10-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
6DFJ
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BU of 6dfj by Molmil
Crystal structure of anti-Zika antibody Z021 bound to DENV-1 envelope protein DIII
分子名称: Dengue 1 Envelope DIII domain, anti-Zika antibody Z021, Heavy Chain, ...
著者Keeffe, J.R, Bjorkman, P.J.
登録日2018-05-14
公開日2018-10-24
最終更新日2018-11-14
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.
Cell Rep, 25, 2018
7R8L
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BU of 7r8l by Molmil
Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody C099 and CR3022
分子名称: C099 Fab Heavy Chain, C099 Fab Light Chain, CR3022 Fab heavy chain, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2021-06-26
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
6XCM
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BU of 6xcm by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2020-06-08
公開日2020-07-01
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
6XCN
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BU of 6xcn by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2020-06-08
公開日2020-07-01
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
6XCA
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BU of 6xca by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C105
分子名称: C105 Heavy Chain, C105 Light Chain, SULFATE ION
著者Sharaf, N.G, Barnes, C.O, Bjorkman, P.J.
登録日2020-06-08
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
6OKP
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BU of 6okp by Molmil
B41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074
分子名称: 10-1074 Heavy Chain,10-1074 Heavy Chain, 10-1074 Light Chain,10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2019-04-14
公開日2019-06-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Immunity, 50, 2019
6ORN
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BU of 6orn by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074
分子名称: 10-1074 antibody Fab heavy chain, 10-1074 antibody Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日2019-04-30
公開日2019-06-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
5VVF
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BU of 5vvf by Molmil
Crystal Structure of 354BG1 Fab
分子名称: 1,2-ETHANEDIOL, 354BG1 Heavy Chain, 354BG1 Light Chain
著者Scharf, L, Gristick, H.B, Bjorkman, P.J.
登録日2017-05-19
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.
Elife, 6, 2017
6OKQ
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BU of 6okq by Molmil
Crystal structure of the SF12 Fab
分子名称: SF12 Fab Heavy Chain,SF12 Fab Heavy Chain, SF12 Fab Light Chain,SF12 Fab Light Chain
著者Barnes, C.O, Bjorkman, P.J.
登録日2019-04-14
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Immunity, 50, 2019
7MXE
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BU of 7mxe by Molmil
Ab1245 Fab in complex with BG505 SOSIP.664 and 8ANC195 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 Fab heavy chain, ...
著者Abernathy, M.E, Bjorkman, P.J.
登録日2021-05-19
公開日2021-10-27
最終更新日2021-11-03
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope.
Npj Vaccines, 6, 2021
3HLA
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BU of 3hla by Molmil
HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN A2.1
分子名称: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A2.1) (ALPHA CHAIN)
著者Saper, M.A, Bjorkman, P.J, Wiley, D.C.
登録日1989-10-06
公開日1990-04-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution.
J.Mol.Biol., 219, 1991
6ORO
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BU of 6oro by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab874NHP antibody Fab heavy chain, ...
著者Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日2019-04-30
公開日2019-06-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
6EDU
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BU of 6edu by Molmil
B41 SOSIP.664 in complex with soluble CD4 (D1-D2), the co-receptor mimicking antibody 21c and the broadly neutralizing antibody 8ANC195
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 21c Fab VH domain, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2018-08-11
公開日2018-10-17
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion.
Cell Host Microbe, 24, 2018
6ORQ
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BU of 6orq by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab275MUR antibody Fab heavy chain, ...
著者Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日2019-04-30
公開日2019-06-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
6ORP
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BU of 6orp by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab897NHP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab897NHP antibody Fab heavy chain, ...
著者Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日2019-04-30
公開日2019-06-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
5I9Q
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BU of 5i9q by Molmil
Crystal structure of 3BNC55 Fab in complex with 426c.TM4deltaV1-3 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC55 Fab heavy chain, ...
著者Scharf, L, Chen, C, Bjorkman, P.J.
登録日2016-02-20
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
8FYI
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BU of 8fyi by Molmil
Structure of HIV-1 BG505 SOSIP-HT1 in complex with one CD4 molecule
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(6-8)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Fan, C, Dam, K.A, Bjorkman, P.J.
登録日2023-01-26
公開日2023-10-18
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Intermediate conformations of CD4-bound HIV-1 Env heterotrimers.
Nature, 623, 2023
8FYJ
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BU of 8fyj by Molmil
Structure of HIV-1 BG505 SOSIP-HT2 in complex with two CD4 molecules (class I)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Fan, C, Dam, K.A, Bjorkman, P.J.
登録日2023-01-26
公開日2023-10-18
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Intermediate conformations of CD4-bound HIV-1 Env heterotrimers.
Nature, 623, 2023
3IT8
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BU of 3it8 by Molmil
Crystal structure of TNF alpha complexed with a poxvirus MHC-related TNF binding protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2L protein, Tumor necrosis factor
著者Yang, Z, West Jr, A.P, Bjorkman, P.J.
登録日2009-08-27
公開日2009-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of TNFalpha complexed with a poxvirus MHC-related TNF binding protein
Nat.Struct.Mol.Biol., 16, 2009
7S0D
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BU of 7s0d by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody N-612-014
分子名称: N-612-014 Fab Heavy Chain, N-612-014 Light Chain, Spike glycoprotein
著者Barnes, C.O, Bjorkman, P.J.
登録日2021-08-30
公開日2021-10-06
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display.
Cell Rep, 38, 2022
7S0B
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BU of 7s0b by Molmil
Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody N-612-056
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-612-056 Fab Heavy Chain, N-612-056 Light Chain, ...
著者Tanaka, S, Barnes, C.O, Bjorkman, P.J.
登録日2021-08-30
公開日2021-10-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display.
Cell Rep, 38, 2022
7S0C
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BU of 7s0c by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody N-612-017
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-612-017 Fab Heavy Chain, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2021-08-30
公開日2021-10-06
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display.
Cell Rep, 38, 2022
7N3G
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BU of 7n3g by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment C098
分子名称: C098 Fab Heavy Chain, C098 Fab Light Chain
著者Flyak, A.I, Bjorkman, P.J, Barnes, C.O.
登録日2021-06-01
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7N3F
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BU of 7n3f by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment C080
分子名称: C080 Fab Heavy Chain, C080 Fab Light Chain
著者Flyak, A.I, Bjorkman, P.J, Barnes, C.O.
登録日2021-06-01
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021

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