7S0C

Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody N-612-017

Summary for 7S0C

• Entry DOI: 10.2210/pdb7s0c/pdb
• EMDB information: 24786
• Descriptor: Spike glycoprotein, N-612-017 Fab Heavy Chain, N-612-017 Light Chain, ... (5 entities in total)
• Functional Keywords: sars-cov-2, antibody, covid-19, spike glycoprotein, mrna display, antiviral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 7
• Total formula weight: 525951.93

Authors

Barnes, C.O.,Bjorkman, P.J. (deposition date: 2021-08-30, release date: 2021-10-06, Last modification date: 2022-03-16)

• Primary citation: Tanaka, S.,Olson, C.A.,Barnes, C.O.,Higashide, W.,Gonzalez, M.,Taft, J.,Richardson, A.,Martin-Fernandez, M.,Bogunovic, D.,Gnanapragasam, P.N.P.,Bjorkman, P.J.,Spilman, P.,Niazi, K.,Rabizadeh, S.,Soon-Shiong, P.; Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display.; Cell Rep, 38:110348-110348, 2022; PubMed: 35114110; DOI: 10.1016/j.celrep.2022.110348

Experimental method

ELECTRON MICROSCOPY (3.25 Å)