1M90
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![BU of 1m90 by Molmil](/molmil-images/mine/1m90) | Co-crystal structure of CCA-Phe-caproic acid-biotin and sparsomycin bound to the 50S ribosomal subunit | Descriptor: | 23S RRNA, 5S RRNA, 6-AMINOHEXANOIC ACID, ... | Authors: | Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A. | Deposit date: | 2002-07-26 | Release date: | 2002-09-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural insights into peptide bond formation. Proc.Natl.Acad.Sci.USA, 99, 2002
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1M5O
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![BU of 1m5o by Molmil](/molmil-images/mine/1m5o) | Transition State Stabilization by a Catalytic RNA | Descriptor: | CALCIUM ION, RNA SUBSTRATE, RNA HAIRPIN RIBOZYME, ... | Authors: | Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R. | Deposit date: | 2002-07-09 | Release date: | 2002-10-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Transition state stabilization by a catalytic RNA Science, 298, 2002
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5N8C
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![BU of 5n8c by Molmil](/molmil-images/mine/5n8c) | Crystal structure of Pseudomonas aeruginosa LpxC complexed with inhibitor | Descriptor: | (2~{S})-3-azanyl-2-[[(1~{R})-5-[2-[4-[[2-(hydroxymethyl)imidazol-1-yl]methyl]phenyl]ethynyl]-2,3-dihydro-1~{H}-inden-1-yl]amino]-3-methyl-~{N}-oxidanyl-butanamide, CHLORIDE ION, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ... | Authors: | Cross, J.B, Ryan, M.D, Zhang, J, Cheng, R.K, Wood, M, Andersen, O.A, Brooks, M, Kwong, J, Barker, J. | Deposit date: | 2017-02-23 | Release date: | 2017-03-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-based discovery of LpxC inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
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4FP9
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![BU of 4fp9 by Molmil](/molmil-images/mine/4fp9) | Human MTERF4-NSUN4 protein complex | Descriptor: | S-ADENOSYLMETHIONINE, SULFATE ION, mTERF domain-containing protein 2, ... | Authors: | Spahr, H, Hallberg, B.M. | Deposit date: | 2012-06-21 | Release date: | 2012-09-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis. Proc.Natl.Acad.Sci.USA, 109, 2012
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1W2F
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![BU of 1w2f by Molmil](/molmil-images/mine/1w2f) | Human Inositol (1,4,5)-trisphosphate 3-kinase substituted with selenomethionine | Descriptor: | INOSITOL-TRISPHOSPHATE 3-KINASE A, SULFATE ION | Authors: | Gonzalez, B, Schell, M.J, Irvine, R.F, Williams, R.L. | Deposit date: | 2004-07-01 | Release date: | 2004-09-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of a Human Inositol 1,4,5-Trisphosphate 3-Kinase; Substrate Binding Reveals Why It is not a Phosphoinositide 3-Kinase Mol.Cell, 15, 2004
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1W2C
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![BU of 1w2c by Molmil](/molmil-images/mine/1w2c) | Human Inositol (1,4,5) trisphosphate 3-kinase complexed with Mn2+/AMPPNP/Ins(1,4,5)P3 | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, INOSITOL-TRISPHOSPHATE 3-KINASE A, MANGANESE (II) ION, ... | Authors: | Gonzalez, B, Schell, M.J, Irvine, R.F, Williams, R.L. | Deposit date: | 2004-07-01 | Release date: | 2004-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of a Human Inositol 1,4,5-Trisphosphate 3-Kinase; Substrate Binding Reveals Why It is not a Phosphoinositide 3-Kinase Mol.Cell, 15, 2004
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3UGM
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![BU of 3ugm by Molmil](/molmil-images/mine/3ugm) | Structure of TAL effector PthXo1 bound to its DNA target | Descriptor: | DNA-1, DNA-2, TAL effector AvrBs3/PthA | Authors: | Mak, A.N.S, Bradley, P, Cernadas, R.A, Bogdanove, A.J, Stoddard, B.L. | Deposit date: | 2011-11-02 | Release date: | 2012-01-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target. Science, 335, 2012
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7NDG
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![BU of 7ndg by Molmil](/molmil-images/mine/7ndg) | Cryo-EM structure of the ternary complex between Netrin-1, Neogenin and Repulsive Guidance Molecule B | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neogenin, ... | Authors: | Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. | Deposit date: | 2021-02-01 | Release date: | 2021-03-31 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (5.98 Å) | Cite: | Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell, 184, 2021
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1M5P
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![BU of 1m5p by Molmil](/molmil-images/mine/1m5p) | Transition State Stabilization by a Catalytic RNA | Descriptor: | CALCIUM ION, RNA HAIRPIN RIBOZYME, RNA INHIBITOR SUBSTRATE, ... | Authors: | Rupert, P.B, Massey, A, Sigurdsson, S.T, Ferre-D'Amare, A.R. | Deposit date: | 2002-07-09 | Release date: | 2002-10-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Transition state stabilization by a catalytic RNA Science, 298, 2002
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4V5V
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![BU of 4v5v by Molmil](/molmil-images/mine/4v5v) | Structure of respiratory syncytial virus nucleocapsid protein, P1 crystal form | Descriptor: | RESPIRATORY SYNCYTIAL VIRUS NUCLEOCAPSID PROTEIN, RNA | Authors: | El Omari, K, Dhaliwal, B, Ren, J, Abrescia, N.G.A, Lockyer, M, Powell, K.L, Hawkins, A.R, Stammers, D.K. | Deposit date: | 2011-05-04 | Release date: | 2014-07-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structures of Respiratory Syncytial Virus Nucleocapsid Protein from Two Crystal Forms: Details of Potential Packing Interactions in the Native Helical Form. Acta Crystallogr.,Sect.F, 67, 2011
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5NHU
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![BU of 5nhu by Molmil](/molmil-images/mine/5nhu) | |
7MSQ
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![BU of 7msq by Molmil](/molmil-images/mine/7msq) | |
5NNJ
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![BU of 5nnj by Molmil](/molmil-images/mine/5nnj) | Dimer structure of Sortilin ectodomain crystal form 3, 4.0 Angstrom | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Sortilin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Leloup, N.O.L, Janssen, B.J.C. | Deposit date: | 2017-04-09 | Release date: | 2017-11-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release. Nat Commun, 8, 2017
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4USZ
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![BU of 4usz by Molmil](/molmil-images/mine/4usz) | Crystal structure of the first bacterial vanadium dependant iodoperoxidase | Descriptor: | SODIUM ION, VANADATE ION, VANADIUM-DEPENDENT HALOPEROXIDASE | Authors: | Rebuffet, E, Delage, L, Fournier, J.B, Rzonca, J, Potin, P, Michel, G, Czjzek, M, Leblanc, C. | Deposit date: | 2014-07-17 | Release date: | 2014-10-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Bacterial Vanadium Iodoperoxidase from the Marine Flavobacteriaceae Zobellia Galactanivorans Reveals Novel Molecular and Evolutionary Features of Halide Specificity in This Enzyme Family. Appl.Environ.Microbiol., 80, 2014
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4UQI
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![BU of 4uqi by Molmil](/molmil-images/mine/4uqi) | AP2 controls clathrin polymerization with a membrane-activated switch | Descriptor: | AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA, AP-2 COMPLEX SUBUNIT MU, ... | Authors: | Kelly, B.T, Graham, S.C, Liska, N, Dannhauser, P.N, Hoening, S, Ungewickell, E.J, Owen, D.J. | Deposit date: | 2014-06-23 | Release date: | 2014-07-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Clathrin Adaptors. Ap2 Controls Clathrin Polymerization with a Membrane-Activated Switch. Science, 345, 2014
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1ML5
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![BU of 1ml5 by Molmil](/molmil-images/mine/1ml5) | Structure of the E. coli ribosomal termination complex with release factor 2 | Descriptor: | 30S 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Klaholz, B.P, Pape, T, Zavialov, A.V, Myasnikov, A.G, Orlova, E.V, Vestergaard, B, Ehrenberg, M, van Heel, M. | Deposit date: | 2002-08-30 | Release date: | 2003-01-14 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (14 Å) | Cite: | Structure of the Escherichia coli ribosomal termination complex with release factor 2 Nature, 421, 2003
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4V5Y
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![BU of 4v5y by Molmil](/molmil-images/mine/4v5y) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with paromomycin and ribosome recycling factor (RRF). | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. | Deposit date: | 2007-06-19 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (4.45 Å) | Cite: | Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
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4V59
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![BU of 4v59 by Molmil](/molmil-images/mine/4v59) | Crystal structure of fatty acid synthase complexed with nadp+ from thermomyces lanuginosus at 3.1 angstrom resolution. | Descriptor: | FATTY ACID SYNTHASE ALPHA SUBUNITS, FATTY ACID SYNTHASE BETA SUBUNITS, FLAVIN MONONUCLEOTIDE, ... | Authors: | Jenni, S, Leibundgut, M, Boehringer, D, Frick, C, Mikolasek, B, Ban, N. | Deposit date: | 2007-03-09 | Release date: | 2014-07-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of Fungal Fatty Acid Synthase and Implications for Iterative Substrate Shuttling Science, 316, 2007
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5VN3
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![BU of 5vn3 by Molmil](/molmil-images/mine/5vn3) | Cryo-EM model of B41 SOSIP.664 in complex with soluble CD4 (D1-D2) and fragment antigen binding variable domain of 17b | Descriptor: | 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ozorowski, G, Pallesen, J, Ward, A.B. | Deposit date: | 2017-04-28 | Release date: | 2017-07-12 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike. Nature, 547, 2017
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8JTR
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![BU of 8jtr by Molmil](/molmil-images/mine/8jtr) | Cryo-EM structure of GeoCas9-sgRNA binary complex | Descriptor: | CRISPR-associated endonuclease Cas9, sgRNA (139-bp) | Authors: | Shen, P.P, Liu, B.B, Li, X, Zhang, L.L, Chen, C.-C, Guo, R.-T. | Deposit date: | 2023-06-22 | Release date: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Cryo-EM structure of GeoCas9-sgRNA binary complex To Be Published
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1VJ5
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![BU of 1vj5 by Molmil](/molmil-images/mine/1vj5) | Human soluble Epoxide Hydrolase- N-cyclohexyl-N'-(4-iodophenyl)urea complex | Descriptor: | HEXAETHYLENE GLYCOL, MAGNESIUM ION, N-CYCLOHEXYL-N'-(4-IODOPHENYL)UREA, ... | Authors: | Gomez, G.A, Morisseau, C, Hammock, B.D, Christianson, D.W. | Deposit date: | 2004-02-03 | Release date: | 2004-04-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis Biochemistry, 43, 2004
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8JTJ
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![BU of 8jtj by Molmil](/molmil-images/mine/8jtj) | Cryo-EM structure of GeoCas9-sgRNA-dsDNA ternary complex | Descriptor: | CRISPR-associated endonuclease Cas9, DNA (29-MER), DNA (5'-D(P*GP*GP*GP*CP*GP*CP*GP*AP*A)-3'), ... | Authors: | Shen, P.P, Liu, B.B, Li, X, Zhang, L.L, Chen, C.-C, Guo, R.-T. | Deposit date: | 2023-06-21 | Release date: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Cryo-EM structure of GeoCas9-sgRNA-DNA ternary complex To Be Published
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1M5V
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![BU of 1m5v by Molmil](/molmil-images/mine/1m5v) | Transition State Stabilization by a Catalytic RNA | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, RNA HAIRPIN RIBOZYME, ... | Authors: | Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R. | Deposit date: | 2002-07-09 | Release date: | 2002-10-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Transition state stabilization by a catalytic RNA Science, 298, 2002
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4V53
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![BU of 4v53 by Molmil](/molmil-images/mine/4v53) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin. | Descriptor: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ... | Authors: | Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. | Deposit date: | 2007-06-16 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.54 Å) | Cite: | Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
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7MNK
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![BU of 7mnk by Molmil](/molmil-images/mine/7mnk) | Crystal structure of the tetramerization element of NUP358/RanBP2 (residues 805-832) | Descriptor: | 1,2-ETHANEDIOL, E3 SUMO-protein ligase RanBP2, SULFATE ION | Authors: | Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. | Deposit date: | 2021-05-01 | Release date: | 2022-06-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
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