4YU5
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![BU of 4yu5 by Molmil](/molmil-images/mine/4yu5) | Crystal structure of selenomethionine variant of Bacillus anthracis immune inhibitor A2 peptidase zymogen | 分子名称: | 3-(1-methylpiperidinium-1-yl)propane-1-sulfonate, CALCIUM ION, GLYCEROL, ... | 著者 | Arolas, J.L, Goulas, T, Gomis-Ruth, F.X. | 登録日 | 2015-03-18 | 公開日 | 2015-10-28 | 最終更新日 | 2016-01-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural Basis for Latency and Function of Immune Inhibitor A Metallopeptidase, a Modulator of the Bacillus anthracis Secretome. Structure, 24, 2016
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4YU6
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![BU of 4yu6 by Molmil](/molmil-images/mine/4yu6) | Crystal structure of Bacillus anthracis immune inhibitor A2 peptidase zymogen | 分子名称: | ACETONITRILE, CALCIUM ION, Immune inhibitor A, ... | 著者 | Arolas, J.L, Goulas, T, Gomis-Ruth, F.X. | 登録日 | 2015-03-18 | 公開日 | 2015-10-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Basis for Latency and Function of Immune Inhibitor A Metallopeptidase, a Modulator of the Bacillus anthracis Secretome. Structure, 24, 2016
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3SSB
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![BU of 3ssb by Molmil](/molmil-images/mine/3ssb) | Structure of Insect Metalloproteinase Inhibitor in Complex with Thermolysin | 分子名称: | CALCIUM ION, GLYCEROL, Inducible metalloproteinase inhibitor protein, ... | 著者 | Arolas, J.L, Botelho, T.O, Vilcinskas, A, Gomis-Ruth, F.X. | 登録日 | 2011-07-08 | 公開日 | 2011-09-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural evidence for standard-mechanism inhibition in metallopeptidases from a complex poised to resynthesize a Peptide bond. Angew.Chem.Int.Ed.Engl., 50, 2011
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1ZLI
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![BU of 1zli by Molmil](/molmil-images/mine/1zli) | Crystal structure of the tick carboxypeptidase inhibitor in complex with human carboxypeptidase B | 分子名称: | Carboxypeptidase B, ZINC ION, carboxypeptidase inhibitor | 著者 | Arolas, J.L, Popowicz, G.M, Lorenzo, J, Sommerhoff, C.P, Huber, R, Aviles, F.X, Holak, T.A. | 登録日 | 2005-05-06 | 公開日 | 2005-07-05 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode J.Mol.Biol., 350, 2005
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1ZFL
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![BU of 1zfl by Molmil](/molmil-images/mine/1zfl) | Solution structure of III-A, the major intermediate in the oxidative folding of leech carboxypeptidase inhibitor | 分子名称: | Metallocarboxypeptidase inhibitor | 著者 | Arolas, J.L, D'Silva, L, Popowicz, G.M, Aviles, F.X, Holak, T.A, Ventura, S. | 登録日 | 2005-04-20 | 公開日 | 2005-09-13 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor STRUCTURE, 13, 2005
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1ZLH
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![BU of 1zlh by Molmil](/molmil-images/mine/1zlh) | Crystal structure of the tick carboxypeptidase inhibitor in complex with bovine carboxypeptidase A | 分子名称: | Carboxypeptidase A1, ZINC ION, carboxypeptidase inhibitor | 著者 | Arolas, J.L, Popowicz, G.M, Lorenzo, J, Sommerhoff, C.P, Huber, R, Aviles, F.X, Holak, T.A. | 登録日 | 2005-05-06 | 公開日 | 2005-07-05 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode J.Mol.Biol., 350, 2005
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2ABZ
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![BU of 2abz by Molmil](/molmil-images/mine/2abz) | Crystal structure of C19A/C43A mutant of leech carboxypeptidase inhibitor in complex with bovine carboxypeptidase A | 分子名称: | Carboxypeptidase A1, Metallocarboxypeptidase inhibitor, ZINC ION | 著者 | Arolas, J.L, Popowicz, G.M, Bronsoms, S, Aviles, F.X, Huber, R, Holak, T.A, Ventura, S. | 登録日 | 2005-07-18 | 公開日 | 2006-01-31 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond J.Mol.Biol., 352, 2005
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1ZFI
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![BU of 1zfi by Molmil](/molmil-images/mine/1zfi) | Solution structure of the leech carboxypeptidase inhibitor | 分子名称: | Metallocarboxypeptidase inhibitor | 著者 | Arolas, J.L, D'Silva, L, Popowicz, G.M, Aviles, F.X, Holak, T.A, Ventura, S. | 登録日 | 2005-04-20 | 公開日 | 2005-09-13 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor STRUCTURE, 13, 2005
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4GWM
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![BU of 4gwm by Molmil](/molmil-images/mine/4gwm) | Crystal structure of human promeprin beta | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Arolas, J.L, Broder, C, Jefferson, T, Guevara, T, Sterchi, E.E, Bode, W, Stocker, W, Becker-Pauly, C, Gomis-Ruth, F.X. | 登録日 | 2012-09-03 | 公開日 | 2012-09-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane Proc.Natl.Acad.Sci.USA, 109, 2012
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4GWN
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![BU of 4gwn by Molmil](/molmil-images/mine/4gwn) | Crystal structure of human mature meprin beta | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Arolas, J.L, Broder, C, Jefferson, T, Guevara, T, Sterchi, E.E, Bode, W, Stocker, W, Becker-Pauly, C, Gomis-Ruth, F.X. | 登録日 | 2012-09-03 | 公開日 | 2012-09-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane Proc.Natl.Acad.Sci.USA, 109, 2012
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3FJU
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![BU of 3fju by Molmil](/molmil-images/mine/3fju) | Ascaris suum carboxypeptidase inhibitor in complex with human carboxypeptidase A1 | 分子名称: | ACETATE ION, CACODYLATE ION, Carboxypeptidase A inhibitor, ... | 著者 | Sanglas, L, Aviles, F.X, Huber, R, Gomis-Ruth, F.X, Arolas, J.L. | 登録日 | 2008-12-15 | 公開日 | 2008-12-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Mammalian metallopeptidase inhibition at the defense barrier of Ascaris parasite Proc.Natl.Acad.Sci.USA, 106, 2009
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3D4U
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![BU of 3d4u by Molmil](/molmil-images/mine/3d4u) | Bovine thrombin-activatable fibrinolysis inhibitor (TAFIa) in complex with tick-derived carboxypeptidase inhibitor. | 分子名称: | ACETATE ION, Carboxypeptidase B2, Carboxypeptidase inhibitor, ... | 著者 | Sanglas, L, Valnickova, Z, Arolas, J.L, Pallares, I, Guevara, T, Sola, M, Kristensen, T, Enghild, J.J, Aviles, F.X, Gomis-Ruth, F.X. | 登録日 | 2008-05-15 | 公開日 | 2008-08-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of activated thrombin-activatable fibrinolysis inhibitor, a molecular link between coagulation and fibrinolysis. Mol.Cell, 31, 2008
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7A8U
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![BU of 7a8u by Molmil](/molmil-images/mine/7a8u) | Crystal structure of sarcomeric protein FATZ-1 (d91-FATZ-1 construct) in complex with rod domain of alpha-actinin-2 | 分子名称: | Alpha-actinin-2, Myozenin-1 | 著者 | Sponga, A, Arolas, J.L, Rodriguez Chamorro, A, Mlynek, G, Hollerl, E, Schreiner, C, Pedron, M, Kostan, J, Ribeiro, E.A, Djinovic-Carugo, K. | 登録日 | 2020-08-31 | 公開日 | 2021-06-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.802 Å) | 主引用文献 | Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with alpha-actinin. Sci Adv, 7, 2021
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7A8T
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![BU of 7a8t by Molmil](/molmil-images/mine/7a8t) | Crystal structure of sarcomeric protein FATZ-1 (mini-FATZ-1 construct) in complex with rod domain of alpha-actinin-2 | 分子名称: | Alpha-actinin-2, Myozenin-1 | 著者 | Sponga, A, Arolas, J.L, Rodriguez Chamorro, A, Mlynek, G, Hollerl, E, Schreiner, C, Pedron, M, Kostan, J, Ribeiro, E.A, Djinovic-Carugo, K. | 登録日 | 2020-08-31 | 公開日 | 2021-06-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with alpha-actinin. Sci Adv, 7, 2021
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7ANK
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![BU of 7ank by Molmil](/molmil-images/mine/7ank) | Crystal structure of sarcomeric protein FATZ-1 (d91-FATZ-1 construct) in complex with half dimer of alpha-actinin-2 | 分子名称: | Alpha-actinin-2, Myozenin-1 | 著者 | Sponga, A, Arolas, J.L, Rodriguez Chamorro, A, Mlynek, G, Hollerl, E, Schreiner, C, Pedron, M, Kostan, J, Ribeiro, E.A, Djinovic-Carugo, K. | 登録日 | 2020-10-12 | 公開日 | 2021-06-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.204 Å) | 主引用文献 | Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with alpha-actinin. Sci Adv, 7, 2021
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3OSL
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![BU of 3osl by Molmil](/molmil-images/mine/3osl) | Structure of bovine thrombin-activatable fibrinolysis inhibitor in complex with tick carboxypeptidase inhibitor | 分子名称: | Carboxypeptidase B2, Carboxypeptidase inhibitor, ZINC ION | 著者 | Valnickova, Z, Sanglas, L, Arolas, J.L, Petersen, S.V, Schar, C, Otzen, D, Aviles, F.X, Gomis-Ruth, F.X, Enghild, J.J. | 登録日 | 2010-09-09 | 公開日 | 2010-09-29 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (6 Å) | 主引用文献 | Flexibility of the Thrombin-activatable Fibrinolysis Inhibitor Pro-domain Enables Productive Binding of Protein Substrates. J.Biol.Chem., 285, 2010
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2XS3
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![BU of 2xs3 by Molmil](/molmil-images/mine/2xs3) | Structure of karilysin catalytic MMP domain | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, KARILYSIN PROTEASE, PEPTIDE ALA-PHE-THR-SER, ... | 著者 | Cerda-Costa, N, Guevara, T, Karim, A.Y, Ksiazek, M, Nguyen, K.-A, Arolas, J.L, Potempa, J, Gomis-Ruth, F.X. | 登録日 | 2010-09-24 | 公開日 | 2010-11-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Structure of the Catalytic Domain of Tannerella Forsythia Karilysin Reveals It is a Bacterial Xenologue of Animal Matrix Metalloproteinases. Mol.Microbiol., 79, 2011
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2XS4
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![BU of 2xs4 by Molmil](/molmil-images/mine/2xs4) | Structure of karilysin catalytic MMP domain in complex with magnesium | 分子名称: | CHLORIDE ION, KARILYSIN PROTEASE, MAGNESIUM ION, ... | 著者 | Cerda-Costa, N, Guevara, T, Karim, A.Y, Ksiazek, M, Nguyen, K.-A, Arolas, J.L, Potempa, J, Gomis-Ruth, F.X. | 登録日 | 2010-09-24 | 公開日 | 2010-11-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Structure of the Catalytic Domain of Tannerella Forsythia Karilysin Reveals It is a Bacterial Xenologue of Animal Matrix Metalloproteinases. Mol.Microbiol., 79, 2011
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8B2N
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![BU of 8b2n by Molmil](/molmil-images/mine/8b2n) | Potempin A (PotA) from Tannerella forsythia in complex with the catalytic domain of human MMP-12 | 分子名称: | CALCIUM ION, Macrophage metalloelastase, Tannerella forsythia potempin A (PotA), ... | 著者 | Potempa, J, Ksiazek, M, Goulas, T, Cuppari, A, Rodriguez-Banqueri, A, Arolas, J.L, Lopez-Pelegrin, M, Garcia-Ferrer, I, Guevara, T. | 登録日 | 2022-09-14 | 公開日 | 2022-12-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A unique network of attack, defence and competence on the outer membrane of the periodontitis pathogen Tannerella forsythia. Chem Sci, 14, 2023
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8B2M
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![BU of 8b2m by Molmil](/molmil-images/mine/8b2m) | Matrix-metallopeptidase inhibitor Potempin A (PotA) from Tannerella forsythia | 分子名称: | NICKEL (II) ION, Tannerella forsythia Potempin A (PotA) | 著者 | Potempa, J, Ksiazek, M, Goulas, T, Cuppari, A, Rodriguez-Banqueri, A, Arolas, J.L, Lopez-Pelegrin, M, Garcia-Ferrer, I, Guevara, T. | 登録日 | 2022-09-14 | 公開日 | 2022-12-21 | 最終更新日 | 2023-02-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A unique network of attack, defence and competence on the outer membrane of the periodontitis pathogen Tannerella forsythia. Chem Sci, 14, 2023
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8B2Q
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![BU of 8b2q by Molmil](/molmil-images/mine/8b2q) | Matrix-metallopeptidase inhibitor Potempin A (PotA) from Tannerella forsythia in complex with T. forsythia karilysin. | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | 著者 | Potempa, J, Ksiazek, M, Goulas, T, Cuppari, A, Rodriguez-Banqueri, A, Arolas, J.L, Lopez-Pelegrin, M, Garcia-Ferrer, I, Guevara, T. | 登録日 | 2022-09-14 | 公開日 | 2022-12-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | A unique network of attack, defence and competence on the outer membrane of the periodontitis pathogen Tannerella forsythia. Chem Sci, 14, 2023
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3LMS
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![BU of 3lms by Molmil](/molmil-images/mine/3lms) | Structure of human activated thrombin-activatable fibrinolysis inhibitor, TAFIa, in complex with tick-derived funnelin inhibitor, TCI. | 分子名称: | CALCIUM ION, CHLORIDE ION, Carboxypeptidase B2, ... | 著者 | Sanglas, L, Arolas, J.L, Valnickova, Z, Aviles, F.X, Enghild, J.J, Gomis-Ruth, F.X. | 登録日 | 2010-02-01 | 公開日 | 2010-02-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Insights into the molecular inactivation mechanism of human activated thrombin-activatable fibrinolysis inhibitor J.Thromb.Haemost., 8, 2010
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3MN8
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![BU of 3mn8 by Molmil](/molmil-images/mine/3mn8) | Structure of Drosophila melanogaster carboxypeptidase D isoform 1B short | 分子名称: | (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | 著者 | Tanco, S, Arolas, J.L, Guevara, T, Lorenzo, J, Aviles, F.X, Gomis-Ruth, F.X. | 登録日 | 2010-04-21 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure-Function Analysis of the Short Splicing Variant Carboxypeptidase Encoded by Drosophila melanogaster silver. J.Mol.Biol., 401, 2010
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3P24
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![BU of 3p24 by Molmil](/molmil-images/mine/3p24) | Structure of profragilysin-3 from Bacteroides fragilis | 分子名称: | AZIDE ION, BFT-3, GLYCEROL, ... | 著者 | Goulas, T, Arolas, J.L, Gomis-Ruth, F.X. | 登録日 | 2010-10-01 | 公開日 | 2010-12-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure, function and latency regulation of a bacterial enterotoxin potentially derived from a mammalian adamalysin/ADAM xenolog. Proc.Natl.Acad.Sci.USA, 108, 2011
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4QHF
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![BU of 4qhf by Molmil](/molmil-images/mine/4qhf) | Crystal structure of Methanocaldococcus jannaschii monomeric selecase | 分子名称: | GLYCEROL, NICKEL (II) ION, Uncharacterized protein MJ1213 | 著者 | Lopez-pelegrin, M, Cerda-costa, N, Cintas-pedrola, A, Herranz-trillo, F, Bernado, P, Peinado, J.R, Arolas, J.L, Gomis-ruth, F.X. | 登録日 | 2014-05-28 | 公開日 | 2014-07-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Multiple stable conformations account for reversible concentration-dependent oligomerization and autoinhibition of a metamorphic metallopeptidase Angew.Chem.Int.Ed.Engl., 53, 2014
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