8B2Q

Matrix-metallopeptidase inhibitor Potempin A (PotA) from Tannerella forsythia in complex with T. forsythia karilysin.

Summary for 8B2Q

• Entry DOI: 10.2210/pdb8b2q/pdb
• Related: 6ZWD
• Descriptor: Karilysin long form Kly38, Tannerella forsythia potempin A (PotA), ZINC ION, ... (7 entities in total)
• Functional Keywords: metallopeptidase inhibitor, hydrolase inhibitor
• Biological source: Tannerella forsythia; More
• Total number of polymer chains: 2
• Total formula weight: 29840.07

Authors

Potempa, J.,Ksiazek, M.,Goulas, T.,Cuppari, A.,Rodriguez-Banqueri, A.,Arolas, J.L.,Lopez-Pelegrin, M.,Garcia-Ferrer, I.,Guevara, T. (deposition date: 2022-09-14, release date: 2022-12-21, Last modification date: 2024-02-07)

• Primary citation: Ksiazek, M.,Goulas, T.,Mizgalska, D.,Rodriguez-Banqueri, A.,Eckhard, U.,Veillard, F.,Waligorska, I.,Benedyk-Machaczka, M.,Sochaj-Gregorczyk, A.M.,Madej, M.,Thogersen, I.B.,Enghild, J.J.,Cuppari, A.,Arolas, J.L.,de Diego, I.,Lopez-Pelegrin, M.,Garcia-Ferrer, I.,Guevara, T.,Dive, V.,Zani, M.L.,Moreau, T.,Potempa, J.,Gomis-Ruth, F.X.; A unique network of attack, defence and competence on the outer membrane of the periodontitis pathogen Tannerella forsythia.; Chem Sci, 14:869-888, 2023; PubMed: 36755705; DOI: 10.1039/d2sc04166a

Experimental method

X-RAY DIFFRACTION (1.35 Å)