3FJU

Ascaris suum carboxypeptidase inhibitor in complex with human carboxypeptidase A1

Summary for 3FJU

• Entry DOI: 10.2210/pdb3fju/pdb
• Related: 2V77
• Descriptor: Carboxypeptidase A1, Carboxypeptidase A inhibitor, ZINC ION, ... (7 entities in total)
• Functional Keywords: ascariasis, host resistance, metallocarboxypeptidase inhibitor, immunolocalization, carboxypeptidase, hydrolase, metal-binding, metalloprotease, protease, secreted, zymogen, metalloenzyme inhibitor, metalloprotease inhibitor, protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P15085 P19399
• Total number of polymer chains: 2
• Total formula weight: 43553.59

Authors

Sanglas, L.,Aviles, F.X.,Huber, R.,Gomis-Ruth, F.X.,Arolas, J.L. (deposition date: 2008-12-15, release date: 2008-12-30, Last modification date: 2023-11-01)

• Primary citation: Sanglas, L.,Aviles, F.X.,Huber, R.,Gomis-Ruth, F.X.,Arolas, J.L.; Mammalian metallopeptidase inhibition at the defense barrier of Ascaris parasite; Proc.Natl.Acad.Sci.USA, 106:1743-1747, 2009; PubMed: 19179285; DOI: 10.1073/pnas.0812623106

Experimental method

X-RAY DIFFRACTION (1.6 Å)