4GWM

Crystal structure of human promeprin beta

Summary for 4GWM

Entry DOI	10.2210/pdb4gwm/pdb
Related	4GWN
Descriptor	Meprin A subunit beta, SODIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total)
Functional Keywords	mulidomain structure, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cell membrane ; Single-pass type I membrane protein: Q16820
Total number of polymer chains	2
Total formula weight	143873.59
Authors	Arolas, J.L.,Broder, C.,Jefferson, T.,Guevara, T.,Sterchi, E.E.,Bode, W.,Stocker, W.,Becker-Pauly, C.,Gomis-Ruth, F.X. (deposition date: 2012-09-03, release date: 2012-09-19, Last modification date: 2020-07-29)
Primary citation	Arolas, J.L.,Broder, C.,Jefferson, T.,Guevara, T.,Sterchi, E.E.,Bode, W.,Stocker, W.,Becker-Pauly, C.,Gomis-Ruth, F.X. Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane Proc.Natl.Acad.Sci.USA, 109:16131-16136, 2012 Cited by PubMed: 22988105 DOI: 10.1073/pnas.1211076109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation