4GWM
Crystal structure of human promeprin beta
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Meprin A subunit beta | polymer | 592 | 67286.7 | 2 | UniProt (Q16820) Pfam (PF01400) Pfam (PF00629) Pfam (PF22486) | Homo sapiens (human) | Endopeptidase-2, Meprin B, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta, PABA peptide hydrolase, PPH beta |
| 2 | C, G (C, G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 3 | D (D) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1203.1 | 1 | In PDB GlyTouCan (G11460AB) | |||
| 4 | E, L (E, L) | alpha-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 2 | In PDB GlyTouCan (G80587NA) | |||
| 5 | F, K (F, K) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1559.4 | 2 | In PDB GlyTouCan (G37135JQ) | |||
| 6 | H (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 7 | I (I) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1041.0 | 1 | In PDB GlyTouCan (G17601US) | |||
| 8 | J (J) | alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 716.7 | 1 | In PDB GlyTouCan (G63564LA) | |||
| 9 | M, S (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 10 | N, T (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 11 | O, U (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 12 | P, Q, V, W, X (A, B) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 13 | R (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 14 | Y, Z (A, B) | water | water | 18.0 | 808 | Chemie (HOH) |
Sequence modifications
A, B: 23 - 614 (UniProt: Q16820)
| PDB | External Database | Details |
|---|---|---|
| Pro 23 | Thr 23 | engineered mutation |
| Trp 24 | Pro 24 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 134573.3 | |
| Branched | Number of molecules | 10 |
| Total formula weight | 8411.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 888.6 | |
| All* | Total formula weight | 143873.6 |
