7A8U
Crystal structure of sarcomeric protein FATZ-1 (d91-FATZ-1 construct) in complex with rod domain of alpha-actinin-2
Summary for 7A8U
Entry DOI | 10.2210/pdb7a8u/pdb |
Related | 7A8T 7ANK |
Descriptor | Alpha-actinin-2, Myozenin-1 (2 entities in total) |
Functional Keywords | z-disk complex, f-actin crosslinking protein, scaffolding protein, fuzzy complex, structural protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 77735.98 |
Authors | Sponga, A.,Arolas, J.L.,Rodriguez Chamorro, A.,Mlynek, G.,Hollerl, E.,Schreiner, C.,Pedron, M.,Kostan, J.,Ribeiro, E.A.,Djinovic-Carugo, K. (deposition date: 2020-08-31, release date: 2021-06-30, Last modification date: 2024-01-31) |
Primary citation | Sponga, A.,Arolas, J.L.,Schwarz, T.C.,Jeffries, C.M.,Rodriguez Chamorro, A.,Kostan, J.,Ghisleni, A.,Drepper, F.,Polyansky, A.,De Almeida Ribeiro, E.,Pedron, M.,Zawadzka-Kazimierczuk, A.,Mlynek, G.,Peterbauer, T.,Doto, P.,Schreiner, C.,Hollerl, E.,Mateos, B.,Geist, L.,Faulkner, G.,Kozminski, W.,Svergun, D.I.,Warscheid, B.,Zagrovic, B.,Gautel, M.,Konrat, R.,Djinovic-Carugo, K. Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with alpha-actinin. Sci Adv, 7:-, 2021 Cited by PubMed: 34049882DOI: 10.1126/sciadv.abg7653 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.802 Å) |
Structure validation
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