7TA8
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![BU of 7ta8 by Molmil](/molmil-images/mine/7ta8) | NMR structure of crosslinked cyclophilin A | 分子名称: | Peptidyl-prolyl cis-trans isomerase A | 著者 | Lu, M, Toptygin, D, Xiang, Y, Shi, Y, Schwieters, C.D, Lipinski, E.C, Ahn, J, Byeon, I.-J.L, Gronenborn, A.M. | 登録日 | 2021-12-20 | 公開日 | 2022-06-01 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The Magic of Linking Rings: Discovery of a Unique Photoinduced Fluorescent Protein Crosslink. J.Am.Chem.Soc., 144, 2022
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4BZB
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![BU of 4bzb by Molmil](/molmil-images/mine/4bzb) | Crystal structure of the tetrameric dGTP-bound SAMHD1 mutant catalytic core | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, MAGNESIUM ION | 著者 | Ji, X, Yang, H, Wu, Y, Yan, J, Mehrens, J, DeLucia, M, Hao, C, Gronenborn, A.M, Skowronski, J, Ahn, J, Xiong, Y. | 登録日 | 2013-07-25 | 公開日 | 2013-10-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Mechanism of Allosteric Activation of Samhd1 by Dgtp Nat.Struct.Mol.Biol., 20, 2013
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4BZC
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![BU of 4bzc by Molmil](/molmil-images/mine/4bzc) | Crystal structure of the tetrameric dGTP-bound wild type SAMHD1 catalytic core | 分子名称: | 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, MAGNESIUM ION, ... | 著者 | Ji, X, Yang, H, Wu, Y, Yan, J, Mehrens, J, DeLucia, M, Hao, C, Gronenborn, A.M, Skowronski, J, Ahn, J, Xiong, Y. | 登録日 | 2013-07-25 | 公開日 | 2013-10-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Mechanism of Allosteric Activation of Samhd1 by Dgtp Nat.Struct.Mol.Biol., 20, 2013
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3J34
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![BU of 3j34 by Molmil](/molmil-images/mine/3j34) | Structure of HIV-1 Capsid Protein by Cryo-EM | 分子名称: | capsid protein | 著者 | Zhao, G, Perilla, J.R, Yufenyuy, E, Meng, X, Chen, B, Ning, J, Ahn, J, Gronenborn, A.M, Schulten, K, Aiken, C, Zhang, P. | 登録日 | 2013-02-23 | 公開日 | 2013-05-29 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (8.6 Å) | 主引用文献 | Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics. Nature, 497, 2013
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5FJB
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![BU of 5fjb by Molmil](/molmil-images/mine/5fjb) | Cyclophilin A Stabilize HIV-1 Capsid through a Novel Non- canonical Binding Site | 分子名称: | GAG POLYPROTEIN, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A | 著者 | Liu, C, Perilla, J.R, Ning, J, Lu, M, Hou, G, Ramalhu, R, Bedwell, G.J, Ahn, J, Shi, J, Gronenborn, A.M, Prevelige Jr, P.E, Rousso, I, Aiken, C, Polenova, T, Schulten, K, Zhang, P. | 登録日 | 2015-10-07 | 公開日 | 2016-03-16 | 最終更新日 | 2017-08-23 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Cyclophilin a Stabilizes the HIV-1 Capsid Through a Novel Non-Canonical Binding Site. Nat.Commun., 7, 2016
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5JK7
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![BU of 5jk7 by Molmil](/molmil-images/mine/5jk7) | The X-ray structure of the DDB1-DCAF1-Vpr-UNG2 complex | 分子名称: | DNA damage-binding protein 1, Protein VPRBP, Protein Vpr, ... | 著者 | Calero, G, Ahn, J, Wu, Y. | 登録日 | 2016-04-26 | 公開日 | 2016-10-05 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | 主引用文献 | The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction. Nat.Struct.Mol.Biol., 23, 2016
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2M65
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![BU of 2m65 by Molmil](/molmil-images/mine/2m65) | NMR structure of human restriction factor APOBEC3A | 分子名称: | Probable DNA dC->dU-editing enzyme APOBEC-3A, ZINC ION | 著者 | Byeon, I.L, Byeon, C, Ahn, J, Gronenborn, A.M. | 登録日 | 2013-03-21 | 公開日 | 2013-05-22 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity. Nat Commun, 4, 2013
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4QFY
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![BU of 4qfy by Molmil](/molmil-images/mine/4qfy) | Crystal structure of the tetrameric dGTP/dCTP-bound SAMHD1 (RN206) mutant catalytic core | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | 登録日 | 2014-05-22 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates. J.Biol.Chem., 289, 2014
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4QG0
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![BU of 4qg0 by Molmil](/molmil-images/mine/4qg0) | Crystal structure of the tetrameric dGTP/dUTP-bound SAMHD1 (RN206) mutant catalytic core | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYURIDINE-5'-TRIPHOSPHATE, ... | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | 登録日 | 2014-05-22 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates. J.Biol.Chem., 289, 2014
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4QG4
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![BU of 4qg4 by Molmil](/molmil-images/mine/4qg4) | Crystal structure of the tetrameric GTP/dATP/ATP-bound SAMHD1 (H210A) mutant catalytic core | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | 登録日 | 2014-05-22 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates. J.Biol.Chem., 289, 2014
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4QG1
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![BU of 4qg1 by Molmil](/molmil-images/mine/4qg1) | Crystal structure of the tetrameric GTP/dATP-bound SAMHD1 (RN206) mutant catalytic core | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | 登録日 | 2014-05-22 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates. J.Biol.Chem., 289, 2014
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4QFX
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![BU of 4qfx by Molmil](/molmil-images/mine/4qfx) | Crystal structure of the tetrameric dGTP/dATP-bound SAMHD1 (RN206) mutant catalytic core | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | 登録日 | 2014-05-21 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates. J.Biol.Chem., 289, 2014
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4QG2
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![BU of 4qg2 by Molmil](/molmil-images/mine/4qg2) | Crystal structure of the tetrameric GTP/dATP/ATP-bound SAMHD1 (RN206) mutant catalytic core | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | 登録日 | 2014-05-22 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates. J.Biol.Chem., 289, 2014
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4QFZ
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![BU of 4qfz by Molmil](/molmil-images/mine/4qfz) | Crystal structure of the tetrameric dGTP/dTTP-bound SAMHD1 (RN206) mutant catalytic core | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, MAGNESIUM ION, ... | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | 登録日 | 2014-05-22 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates. J.Biol.Chem., 289, 2014
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4Z8L
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![BU of 4z8l by Molmil](/molmil-images/mine/4z8l) | Crystal structure of DCAF1/SIV-MND VPX/MND SAMHD1 NTD ternary complex | 分子名称: | Protein VPRBP, SAM domain and HD domain-containing protein, Vpx protein, ... | 著者 | Koharudin, L.M, Wu, Y, Calero, G, Ahn, J, Gronenborn, A.M. | 登録日 | 2015-04-09 | 公開日 | 2015-06-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile alpha Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors. J.Biol.Chem., 290, 2015
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5YDV
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![BU of 5ydv by Molmil](/molmil-images/mine/5ydv) | Regulatory domain of HypT from Salmonella typhimurium complexed with HOCl (HOCl-bound form) | 分子名称: | Cell density-dependent motility repressor, SULFATE ION, hypochlorous acid | 著者 | Jo, I, Hong, S, Ahn, J, Ha, N.C. | 登録日 | 2017-09-14 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.752 Å) | 主引用文献 | Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5YEZ
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![BU of 5yez by Molmil](/molmil-images/mine/5yez) | Regulatory domain of HypT M206Q mutant from Salmonella typhimurium | 分子名称: | Cell density-dependent motility repressor | 著者 | Jo, I, Hong, S, Ahn, J, Ha, N.C. | 登録日 | 2017-09-20 | 公開日 | 2018-10-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5YDW
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![BU of 5ydw by Molmil](/molmil-images/mine/5ydw) | Full-length structure of HypT from Salmonella typhimuriuma (hypochlorite-specific LysR-type transcriptional regulator) | 分子名称: | Cell density-dependent motility repressor | 著者 | Jo, I, Hong, S, Ahn, J, Ha, N.C. | 登録日 | 2017-09-15 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5Y9S
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![BU of 5y9s by Molmil](/molmil-images/mine/5y9s) | Crystal structure of VV2_1132, a LysR family transcriptional regulator | 分子名称: | BROMIDE ION, VV2_1132 | 著者 | Jang, Y, Hong, S, Jo, I, Ahn, J, Ha, N.C. | 登録日 | 2017-08-28 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | A Novel Tetrameric Assembly Configuration in VV2_1132, a LysR-Type Transcriptional Regulator inVibrio vulnificus Mol. Cells, 41, 2018
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5YER
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![BU of 5yer by Molmil](/molmil-images/mine/5yer) | Regulatory domain of HypT from Salmonella typhimurium (Bromide ion-bound) | 分子名称: | BROMIDE ION, Cell density-dependent motility repressor, SULFATE ION | 著者 | Jo, I, Hong, S, Ahn, J, Ha, N.C. | 登録日 | 2017-09-19 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5YDO
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![BU of 5ydo by Molmil](/molmil-images/mine/5ydo) | Regulatory domain of HypT from Salmonella typhimurium (apo-form) | 分子名称: | Cell density-dependent motility repressor, SULFATE ION | 著者 | Jo, I, Hong, S, Ahn, J, Ha, N.C. | 登録日 | 2017-09-13 | 公開日 | 2018-11-28 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5ZNX
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![BU of 5znx by Molmil](/molmil-images/mine/5znx) | Crystal structure of CM14-treated HlyU from Vibrio vulnificus | 分子名称: | Transcriptional activator | 著者 | Park, N, Kim, S, Jo, I, Ahn, J, Hong, S, Jeong, S, Baek, Y. | 登録日 | 2018-04-11 | 公開日 | 2019-04-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.114 Å) | 主引用文献 | Small-molecule inhibitor of HlyU attenuates virulence of Vibrio species. Sci Rep, 9, 2019
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7T8C
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![BU of 7t8c by Molmil](/molmil-images/mine/7t8c) | Heptameric Human Twinkle Helicase Clinical Variant W315L | 分子名称: | Twinkle mtDNA helicase | 著者 | Riccio, A.A, Bouvette, J, Krahn, J, Borgnia, M.J, Copeland, W.C. | 登録日 | 2021-12-16 | 公開日 | 2022-07-27 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural insight and characterization of human Twinkle helicase in mitochondrial disease. Proc.Natl.Acad.Sci.USA, 119, 2022
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7T8B
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![BU of 7t8b by Molmil](/molmil-images/mine/7t8b) | Octameric Human Twinkle Helicase Clinical Variant W315L | 分子名称: | Twinkle mtDNA helicase | 著者 | Riccio, A.A, Bouvette, J, Krahn, J, Borgnia, M.J, Copeland, W.C. | 登録日 | 2021-12-16 | 公開日 | 2022-07-27 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural insight and characterization of human Twinkle helicase in mitochondrial disease. Proc.Natl.Acad.Sci.USA, 119, 2022
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5FIY
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![BU of 5fiy by Molmil](/molmil-images/mine/5fiy) | crystal structure of coiled coil domain of PAWR | 分子名称: | POTASSIUM ION, PRKC APOPTOSIS WT1 REGULATOR PROTEIN | 著者 | Tiruttani Subhramanyam, U.K, Kubicek, J, Eidhoff, U.B, Labahn, J. | 登録日 | 2015-10-03 | 公開日 | 2016-11-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the regulatory interactions of proapoptotic Par-4. Cell Death Differ., 24, 2017
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