7T8C
Heptameric Human Twinkle Helicase Clinical Variant W315L
Summary for 7T8C
| Entry DOI | 10.2210/pdb7t8c/pdb |
| EMDB information | 25744 |
| Descriptor | Twinkle mtDNA helicase (1 entity in total) |
| Functional Keywords | helicase, walker a, walker b, dna binding, dna binding protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 7 |
| Total formula weight | 549285.95 |
| Authors | Riccio, A.A.,Bouvette, J.,Krahn, J.,Borgnia, M.J.,Copeland, W.C. (deposition date: 2021-12-16, release date: 2022-07-27, Last modification date: 2024-02-28) |
| Primary citation | Riccio, A.A.,Bouvette, J.,Perera, L.,Longley, M.J.,Krahn, J.M.,Williams, J.G.,Dutcher, R.,Borgnia, M.J.,Copeland, W.C. Structural insight and characterization of human Twinkle helicase in mitochondrial disease. Proc.Natl.Acad.Sci.USA, 119:e2207459119-e2207459119, 2022 Cited by PubMed: 35914129DOI: 10.1073/pnas.2207459119 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (4.5 Å) |
Structure validation
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