5FJB
Cyclophilin A Stabilize HIV-1 Capsid through a Novel Non- canonical Binding Site
Summary for 5FJB
Entry DOI | 10.2210/pdb5fjb/pdb |
EMDB information | 3076 |
Descriptor | GAG POLYPROTEIN, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (2 entities in total) |
Functional Keywords | isomerase |
Biological source | HUMAN IMMUNODEFICIENCY VIRUS 1 More |
Cellular location | Gag polyprotein: Host cell membrane ; Lipid-anchor . Matrix protein p17: Virion membrane ; Lipid-anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion : P03347 Cytoplasm : P62937 |
Total number of polymer chains | 3 |
Total formula weight | 66597.13 |
Authors | Liu, C.,Perilla, J.R.,Ning, J.,Lu, M.,Hou, G.,Ramalhu, R.,Bedwell, G.J.,Ahn, J.,Shi, J.,Gronenborn, A.M.,Prevelige Jr, P.E.,Rousso, I.,Aiken, C.,Polenova, T.,Schulten, K.,Zhang, P. (deposition date: 2015-10-07, release date: 2016-03-16, Last modification date: 2017-08-23) |
Primary citation | Liu, C.,Perilla, J.R.,Ning, J.,Lu, M.,Hou, G.,Ramalho, R.,Himes, B.A.,Zhao, G.,Bedwell, G.J.,Byeon, I.,Ahn, J.,Gronenborn, A.M.,Prevelige, P.E.,Rousso, I.,Aiken, C.,Polenova, T.,Schulten, K.,Zhang, P. Cyclophilin a Stabilizes the HIV-1 Capsid Through a Novel Non-Canonical Binding Site. Nat.Commun., 7:10714-, 2016 Cited by PubMed: 26940118DOI: 10.1038/NCOMMS10714 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (9 Å) |
Structure validation
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