6JU0
| Mouse antibody 3.3 Fab in complex with PEG | Descriptor: | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, Fab heavy chain, ... | Authors: | Lee, C.C, Ko, T.P, Lin, L.L, Wang, A.H.J. | Deposit date: | 2019-04-12 | Release date: | 2020-02-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Structural basis of polyethylene glycol recognition by antibody. J.Biomed.Sci., 27, 2020
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6JXG
| Crystasl Structure of Beta-glucosidase D2-BGL from Chaetomella Raphigera | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-glucosidase, alpha-D-mannopyranose | Authors: | Wang, A.H.-J, Lee, C.C, Kao, M.R, Ho, T.H.D. | Deposit date: | 2019-04-23 | Release date: | 2019-11-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Chaetomella raphigerabeta-glucosidase D2-BGL has intriguing structural features and a high substrate affinity that renders it an efficient cellulase supplement for lignocellulosic biomass hydrolysis. Biotechnol Biofuels, 12, 2019
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6JP7
| Human antibody 32D6 Fab in complex with PEG | Descriptor: | (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, HEXAETHYLENE GLYCOL, immunoglobulin Fab heavy chain, ... | Authors: | Lee, C.C, Ko, T.P, Lin, L.L, Wang, A.H.J. | Deposit date: | 2019-03-26 | Release date: | 2020-02-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.909 Å) | Cite: | Structural basis of polyethylene glycol recognition by antibody. J.Biomed.Sci., 27, 2020
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6JWC
| Mouse antibody 2B5 Fab in complex with PEG | Descriptor: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, DI(HYDROXYETHYL)ETHER, DODECAETHYLENE GLYCOL, ... | Authors: | Lee, C.C, Ko, T.P, Su, Y.C, Lin, L.L, Roffler, S.R, Wang, A.H.J. | Deposit date: | 2019-04-19 | Release date: | 2020-02-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.297 Å) | Cite: | Structural basis of polyethylene glycol recognition by antibody. J.Biomed.Sci., 27, 2020
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6M7W
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6MI3
| Structure of NEMO(51-112) with N- and C-terminal coiled-coil adaptors. | Descriptor: | NF-kB ESSENTIAL MODULATOR,NF-kappa-B essential modulator,NF-kB ESSENTIAL MODULATOR | Authors: | Pellegrini, M, Barczewski, A.H, Mierke, D.F, Ragusa, M.J. | Deposit date: | 2018-09-19 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.783 Å) | Cite: | The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface. Sci Rep, 9, 2019
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6MI4
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6SXI
| Antibody-anti-idiotype complex: AP33 Fab (hepatitis C virus E2 antibody) - B2.1A scFv (anti-idiotype) | Descriptor: | Fab heavy chain, Fab light chain, GLYCEROL, ... | Authors: | Taylor, G.L, Potter, J.A, Fadda, V, Patel, A.H, Owsianka, A.M, Cowtan, V.M. | Deposit date: | 2019-09-26 | Release date: | 2020-10-07 | Last modified: | 2021-01-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design. NPJ Vaccines, 6, 2021
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6PK3
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6PPC
| Solution structure of conotoxin MiXXVIIA | Descriptor: | Conopeptide phi-MiXXVIIA | Authors: | Daly, N.L, Dekan, Z, Jin, A.H, Alewood, P.F. | Deposit date: | 2019-07-06 | Release date: | 2019-08-14 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Conotoxin phi-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity. Angew. Chem. Int. Ed. Engl., 56, 2017
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6PK1
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6PQ3
| Crystal structure of GDP-bound KRAS with ten residues long internal tandem duplication in the switch II region | Descriptor: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Dharmaiah, S, Chan, A.H, Tran, T.H, Simanshu, D.K. | Deposit date: | 2019-07-08 | Release date: | 2020-05-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | RASinternal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signaling. J.Biol.Chem., 295, 2020
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6N6Q
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5MPQ
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6PXF
| Structure of human Cathepsin K with an ectosteric inhibitor at 1.85 Angstrom resolution | Descriptor: | 1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonic acid, Cathepsin K | Authors: | Law, S, Aguda, A.H, Nguyen, N.T, Brayer, G.D, Bromme, D. | Deposit date: | 2019-07-25 | Release date: | 2020-07-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of human Cathepsin K with an ectosteric inhibitor at 1.85 Angstrom resolution To Be Published
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8I4F
| Omicron spike variant XBB with n3130v-Fc | Descriptor: | Spike glycoprotein, n3130v-Fc | Authors: | Hao, A.H, Zhang, X, Chen, Z.G, Sun, L. | Deposit date: | 2023-01-19 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants. Signal Transduct Target Ther, 8, 2023
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8I4G
| Omicron spike variant BQ.1.1 with n3130v-Fc | Descriptor: | Spike glycoprotein, n3130v-Fc | Authors: | Hao, A.H, Zhang, X, Chen, Z.G, Sun, L. | Deposit date: | 2023-01-19 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants. Signal Transduct Target Ther, 8, 2023
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8I4E
| Omicron spike variant XBB with Bn03 | Descriptor: | Bn03, Spike glycoprotein | Authors: | Hao, A.H, Zhang, X, Chen, Z.G, Sun, L. | Deposit date: | 2023-01-19 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.98 Å) | Cite: | Defining a highly conserved cryptic epitope for antibody recognition of SARS-CoV-2 variants. Signal Transduct Target Ther, 8, 2023
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6NI2
| Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta-arrestin mega-complex | Descriptor: | Beta-arrestin-1, Fab30 Heavy Chain, Fab30 Light Chain, ... | Authors: | Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J. | Deposit date: | 2018-12-26 | Release date: | 2019-11-20 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex. Nat.Struct.Mol.Biol., 26, 2019
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6NI3
| B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex | Descriptor: | 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Endolysin,Beta-2 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J. | Deposit date: | 2018-12-26 | Release date: | 2019-11-20 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex. Nat.Struct.Mol.Biol., 26, 2019
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6PT8
| Crystal Structure of CobT from Methanocaldococcus jannaschii in complex with Adenine Alpha-Ribotide and Nicotinic Acid | Descriptor: | ALPHA-ADENOSINE MONOPHOSPHATE, NICOTINIC ACID, PHOSPHATE ION, ... | Authors: | Schwarzwalder, A.H, Jeter, V.L, Vecellio, A.A, Erpenbach, E, Escalante, J.C, Rayment, I. | Deposit date: | 2019-07-15 | Release date: | 2020-07-22 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural studies of the phosphoribosyltransferase involved in cobamide biosynthesis in methanogenic archaea and cyanobacteria. Sci Rep, 12, 2022
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6NQM
| Crystal structure of Human LSD1 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A | Authors: | Tan, A.H.Y, Tu, W, McCuaig, R, Donovan, T, Tsimbalyuk, S, Forwood, J.K, Rao, S. | Deposit date: | 2019-01-21 | Release date: | 2019-02-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer. Front Immunol, 10, 2019
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6PTF
| Crystal Structure of CobT from Methanocaldococcus jannaschii in Apo State | Descriptor: | UPF0284 protein MJ1598 | Authors: | Schwarzwalder, A.H, Jeter, V.L, Vecellio, A.A, Erpenbach, E, Escalante-Semerena, J.C, Rayment, I. | Deposit date: | 2019-07-15 | Release date: | 2020-07-22 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.203 Å) | Cite: | Structural studies of the phosphoribosyltransferase involved in cobamide biosynthesis in methanogenic archaea and cyanobacteria. Sci Rep, 12, 2022
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6QCM
| Cryo em structure of the Listeria stressosome | Descriptor: | RsbR protein, RsbR protein,RsbR protein, RsbS protein | Authors: | Williams, A.H, Redzej, A, Waksman, G, Cossart, P. | Deposit date: | 2018-12-28 | Release date: | 2019-08-21 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.21 Å) | Cite: | The cryo-electron microscopy supramolecular structure of the bacterial stressosome unveils its mechanism of activation. Nat Commun, 10, 2019
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6NBL
| Cytochrome P450cam-putidaredoxin complex bound to camphor and cyanide | Descriptor: | 1,1'-hexane-1,6-diyldipyrrolidine-2,5-dione, CALCIUM ION, CAMPHOR, ... | Authors: | Follmer, A.H, Tripathi, S.M, Poulos, T.L. | Deposit date: | 2018-12-07 | Release date: | 2019-03-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Ligand and Redox Partner Binding Generates a New Conformational State in Cytochrome P450cam (CYP101A1). J. Am. Chem. Soc., 141, 2019
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