6MI4

Structure of the I65M mutant of NEMO(51-112) with N- and C-terminal coiled-coil adaptors.

Summary for 6MI4

• Entry DOI: 10.2210/pdb6mi4/pdb
• Related: 6MI3
• Descriptor: NF-kB ESSENTIAL MODULATOR (2 entities in total)
• Functional Keywords: coiled coil, scaffolding, nf-kb pathway, transcription
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 29507.23

Authors

Pellegrini, M.,Barczewski, A.H.,Mierke, D.F.,Ragusa, M.J. (deposition date: 2018-09-19, release date: 2019-08-07, Last modification date: 2023-11-15)

• Primary citation: Barczewski, A.H.,Ragusa, M.J.,Mierke, D.F.,Pellegrini, M.; The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface.; Sci Rep, 9:2950-2950, 2019; PubMed: 30814588; DOI: 10.1038/s41598-019-39588-2

Experimental method

X-RAY DIFFRACTION (2.50009425402 Å)