6JWC

Mouse antibody 2B5 Fab in complex with PEG

Summary for 6JWC

• Entry DOI: 10.2210/pdb6jwc/pdb
• Related: 6JU0
• Descriptor: Immunoglobulin heavy chain Fab fragment, Immunoglobulin light chain, SULFATE ION, ... (7 entities in total)
• Functional Keywords: antibody fab, influenza hemagglutinin, complex structure, specific binding, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 2
• Total formula weight: 49904.44

Authors

Lee, C.C.,Ko, T.P.,Su, Y.C.,Lin, L.L.,Roffler, S.R.,Wang, A.H.J. (deposition date: 2019-04-19, release date: 2020-02-05, Last modification date: 2024-11-20)

Primary citation

Lee, C.C.,Su, Y.C.,Ko, T.P.,Lin, L.L.,Yang, C.Y.,Chang, S.S.,Roffler, S.R.,Wang, A.H.
Structural basis of polyethylene glycol recognition by antibody.
J.Biomed.Sci., 27:12-12, 2020

PubMed Abstract: Polyethylene glycol (PEG) is widely used in industry and medicine. Anti-PEG antibodies have been developed for characterizing PEGylated drugs and other applications. However, the underlying mechanism for specific PEG binding has not been elucidated.

PubMed: 31907057
DOI: 10.1186/s12929-019-0589-7

Experimental method

X-RAY DIFFRACTION (2.297 Å)