2IG3
 
 | | Crystal structure of group III truncated hemoglobin from Campylobacter jejuni | | Descriptor: | ACETATE ION, CYANIDE ION, Group III truncated haemoglobin, ... | | Authors: | Nardini, M, Pesce, A, Labarre, M, Ascenzi, P, Guertin, M, Bolognesi, M. | | Deposit date: | 2006-09-22 | | Release date: | 2006-10-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural determinants in the group III truncated hemoglobin from Campylobacter jejuni.
J.Biol.Chem., 281, 2006
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4RPJ
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2IGS
 | | Crystal Structure of the Protein of Unknown Function from Pseudomonas aeruginosa | | Descriptor: | ACETIC ACID, GLYCEROL, Hypothetical protein, ... | | Authors: | Kim, Y, Joachimiak, A, Skarina, T, Egorova, O, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2006-09-25 | | Release date: | 2006-10-24 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Crystal Structure of the Hypothetical Protein from Pseudomonas aeruginosa
To be Published
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1TIJ
 | | 3D Domain-swapped human cystatin C with amyloid-like intermolecular beta-sheets | | Descriptor: | Cystatin C | | Authors: | Janowski, R, Kozak, M, Abrahamson, M, Grubb, A, Jaskolski, M. | | Deposit date: | 2004-06-02 | | Release date: | 2005-07-19 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.03 Å) | | Cite: | 3D domain-swapped human cystatin C with amyloidlike intermolecular beta-sheets.
Proteins, 61, 2005
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4RQQ
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7TGT
 | | Structure of Cyclophilin D Peptidyl-Prolyl Isomerase Domain bound to Macrocyclic Inhibitor A26 | | Descriptor: | (4S,7S,11R,13E,19S)-N-[2-(2-aminoethoxy)ethyl]-7-benzyl-4-[(furan-2-yl)methyl]-3,6,12,15,21-pentaoxo-1,3,4,5,6,7,8,9,10,12,15,16,17,18,19,20,21,22-octadecahydro-2H-7,11-methano-2,5,11,16,20-benzopentaazacyclotetracosine-19-carboxamide, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | | Authors: | Rangwala, A.M, Seeliger, M.A, Peterson, A.A, Liu, D.R. | | Deposit date: | 2022-01-09 | | Release date: | 2022-08-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.06 Å) | | Cite: | Discovery and molecular basis of subtype-selective cyclophilin inhibitors.
Nat.Chem.Biol., 18, 2022
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2IK4
 | | Yeast inorganic pyrophosphatase variant D117E with magnesium and phosphate | | Descriptor: | Inorganic pyrophosphatase, MAGNESIUM ION, PHOSPHATE ION | | Authors: | Oksanen, E, Ahonen, A.K, Tuominen, H, Tuominen, V, Lahti, R, Goldman, A, Heikinheimo, P. | | Deposit date: | 2006-10-02 | | Release date: | 2007-02-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase.
Biochemistry, 46, 2007
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1ST9
 | | Crystal Structure of a Soluble Domain of ResA in the Oxidised Form | | Descriptor: | 1,2-ETHANEDIOL, Thiol-disulfide oxidoreductase resA | | Authors: | Crow, A, Acheson, R.M, Le Brun, N.E, Oubrie, A. | | Deposit date: | 2004-03-25 | | Release date: | 2004-05-11 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural Basis of Redox-coupled Protein Substrate Selection by the Cytochrome c Biosynthesis Protein ResA.
J.Biol.Chem., 279, 2004
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1SUS
 | | Crystal structure of alfalfa feruoyl coenzyme A 3-O-methyltransferase | | Descriptor: | CALCIUM ION, Caffeoyl-CoA O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Ferrer, J.-L, Zubieta, C, Dixon, R.A, Noel, J.P. | | Deposit date: | 2004-03-26 | | Release date: | 2005-03-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structures of Alfalfa Caffeoyl Coenzyme A 3-O-Methyltransferase
Plant Physiol., 137, 2005
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3EXC
 | | Structure of the RNA'se SSO8090 from Sulfolobus solfataricus | | Descriptor: | CHLORIDE ION, SODIUM ION, Uncharacterized protein | | Authors: | Singer, A.U, Skarina, T, Tan, K, Kagan, O, Onopriyenko, O, Edwards, A.M, Joachimiak, A, Yakunin, A.F, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2008-10-16 | | Release date: | 2008-11-11 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structure of the RNA'se SSO8090 from Sulfolobus solfataricus
To be Published
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2IWB
 | | MecR1 unbound extracellular antibiotic-sensor domain. | | Descriptor: | GLYCEROL, METHICILLIN RESISTANCE MECR1 PROTEIN, NICKEL (II) ION, ... | | Authors: | Marrero, A, Mallorqui-Fernandez, G, Guevara, T, Garcia-Castellanos, R, Gomis-Ruth, F.X. | | Deposit date: | 2006-06-27 | | Release date: | 2006-07-04 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Unbound and Acylated Structures of the Mecr1 Extracellular Antibiotic-Sensor Domain Provide Insights Into the Signal-Transduction System that Triggers Methicillin Resistance.
J.Mol.Biol., 361, 2006
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1T8E
 | | T7 DNA Polymerase Ternary Complex with dCTP at the Insertion Site. | | Descriptor: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 25-MER, ... | | Authors: | Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. | | Deposit date: | 2004-05-12 | | Release date: | 2004-10-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase.
Embo J., 23, 2004
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4RXG
 | | Fructose-6-phosphate aldolase Q59E from E.coli | | Descriptor: | Fructose-6-phosphate aldolase 1, GLYCEROL, PENTAETHYLENE GLYCOL | | Authors: | Stellmacher, L, Sandalova, T, Leptihn, S, Schneider, G, Sprenger, G.A, Samland, A.K. | | Deposit date: | 2014-12-11 | | Release date: | 2015-10-07 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.154 Å) | | Cite: | Acid Base Catalyst Discriminates between a Fructose 6-Phosphate Aldolase and a Transaldolase
ChemCatChem, 2015
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1T39
 | | HUMAN O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE COVALENTLY CROSSLINKED TO DNA | | Descriptor: | 5'-D(*GP*CP*CP*AP*TP*GP*(E1X)P*CP*TP*AP*GP*TP*A)-3', 5'-D(*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3', Methylated-DNA--protein-cysteine methyltransferase | | Authors: | Daniels, D.S, Woo, T.T, Luu, K.X, Noll, D.M, Clarke, N.D, Pegg, A.E, Tainer, J.A. | | Deposit date: | 2004-04-25 | | Release date: | 2004-07-13 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | DNA binding and nucleotide flipping by the human DNA repair protein AGT.
Nat.Struct.Mol.Biol., 11, 2004
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2INQ
 | | Neutron Crystal Structure of Escherichia coli Dihydrofolate Reductase Bound to the Anti-cancer drug, Methotrexate | | Descriptor: | Dihydrofolate reductase, N-(4-{[(2,4-DIAMINOPTERIDIN-1-IUM-6-YL)METHYL](METHYL)AMINO}BENZOYL)-L-GLUTAMIC ACID | | Authors: | Bennett, B.C, Langan, P.A, Coates, L, Schoenborn, B, Dealwis, C.G. | | Deposit date: | 2006-10-08 | | Release date: | 2007-02-06 | | Last modified: | 2023-08-30 | | Method: | NEUTRON DIFFRACTION (2.2 Å) | | Cite: | Neutron diffraction studies of Escherichia coli dihydrofolate reductase complexed with methotrexate.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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7SVM
 | | DPP8 IN COMPLEX WITH LIGAND ICeD-2 | | Descriptor: | (2S)-2-amino-1-(1,3-dihydro-2H-isoindol-2-yl)-2-[(1r,4S)-4-(pyrrolidin-1-yl)cyclohexyl]ethan-1-one, Dipeptidyl peptidase 8, trimethylamine oxide | | Authors: | Lammens, A, Hollenstein, K, Klein, D.J. | | Deposit date: | 2021-11-19 | | Release date: | 2022-10-05 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
Acs Chem.Biol., 17, 2022
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7SVN
 | | DPP9 IN COMPLEX WITH LIGAND ICeD-1 | | Descriptor: | (2S,4S)-1-[(2S)-2-amino-2-cyclohexylacetyl]-4-fluoropyrrolidine-2-carbonitrile, Dipeptidyl peptidase 9 | | Authors: | Lammens, A, Hollenstein, K, Klein, D.J. | | Deposit date: | 2021-11-19 | | Release date: | 2022-10-05 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
Acs Chem.Biol., 17, 2022
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7SVO
 | | DPP8 IN COMPLEX WITH LIGAND ICeD-1 | | Descriptor: | (2S,4S)-1-[(2S)-2-amino-2-cyclohexylacetyl]-4-fluoropyrrolidine-2-carbonitrile, Dipeptidyl peptidase 8, trimethylamine oxide | | Authors: | Lammens, A, Hollenstein, K, Klein, D.J. | | Deposit date: | 2021-11-19 | | Release date: | 2022-10-05 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.58 Å) | | Cite: | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
Acs Chem.Biol., 17, 2022
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1SZ2
 | | Crystal structure of E. coli glucokinase in complex with glucose | | Descriptor: | Glucokinase, beta-D-glucopyranose | | Authors: | Lunin, V.V, Li, Y, Schrag, J.D, Iannuzzi, P, Matte, A, Cygler, M. | | Deposit date: | 2004-04-02 | | Release date: | 2004-11-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of Escherichia coli ATP-dependent glucokinase and its complex with glucose
J.Bacteriol., 186, 2004
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3F0W
 | | Human NUMB-like protein, phosphotyrosine interaction domain | | Descriptor: | CHLORIDE ION, Numb-like protein, SULFATE ION | | Authors: | Lehtio, L, Moche, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Bountra, C, D Busam, R, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-10-27 | | Release date: | 2008-11-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Human NUMB-like protein, phosphotyrosine interaction domain
To be Published
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6IXI
 | | structure of Cd-bound periplasmic metal binding protein from candidatus liberibacter asiaticus | | Descriptor: | ACETATE ION, CADMIUM ION, GLYCEROL, ... | | Authors: | Kumar, P, Sharma, N, Dalal, V, Ghosh, D.K, Kumar, P, Sharma, A.K. | | Deposit date: | 2018-12-10 | | Release date: | 2020-01-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Characterization of the heavy metal binding properties of periplasmic metal uptake protein CLas-ZnuA2.
Metallomics, 12, 2020
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1T38
 | | HUMAN O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE BOUND TO DNA CONTAINING O6-METHYLGUANINE | | Descriptor: | 5'-D(*GP*CP*CP*AP*TP*GP*(6OG)P*CP*TP*AP*GP*TP*A)-3', 5'-D(*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3', Methylated-DNA--protein-cysteine methyltransferase | | Authors: | Daniels, D.S, Woo, T.T, Luu, K.X, Noll, D.M, Clarke, N.D, Pegg, A.E, Tainer, J.A. | | Deposit date: | 2004-04-25 | | Release date: | 2004-07-13 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | DNA binding and nucleotide flipping by the human DNA repair protein AGT.
Nat.Struct.Mol.Biol., 11, 2004
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2I07
 | | Human Complement Component C3b | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3b, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Janssen, B.J.C, Christodoulidou, A, McCarthy, A, Lambris, J.D, Gros, P. | | Deposit date: | 2006-08-10 | | Release date: | 2006-10-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structure of C3b reveals conformational changes that underlie complement activity.
Nature, 444, 2006
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1TG2
 | | Crystal structure of phenylalanine hydroxylase A313T mutant with 7,8-dihydrobiopterin bound | | Descriptor: | 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE, FE (III) ION, Phenylalanine-4-hydroxylase | | Authors: | Erlandsen, H, Pey, A.L, Gamez, A, Perez, B, Desviat, L.R, Aguado, C, Koch, R, Surendran, S, Tyring, S, Matalon, R, Scriver, C.R, Ugarte, M, Martinez, A, Stevens, R.C. | | Deposit date: | 2004-05-28 | | Release date: | 2004-11-30 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations.
Proc.Natl.Acad.Sci.Usa, 101, 2004
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3ES5
 | | Crystal Structure of Partitivirus (PsV-F) | | Descriptor: | Putative capsid protein | | Authors: | Pan, J, Dong, L, Lin, L, Ochoa, W.F, Sinkovits, R.S, Havens, W.M, Nibert, M.L, Baker, T.S, Ghabrial, S.A, Tao, Y.J. | | Deposit date: | 2008-10-03 | | Release date: | 2009-03-10 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Atomic structure reveals the unique capsid organization of a dsRNA virus.
Proc.Natl.Acad.Sci.USA, 106, 2009
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