2IWB

MecR1 unbound extracellular antibiotic-sensor domain.

Summary for 2IWB

Entry DOI	10.2210/pdb2iwb/pdb
Related	2IWC 2IWD
Descriptor	METHICILLIN RESISTANCE MECR1 PROTEIN, TETRAPEPTIDE, NICKEL (II) ION, ... (5 entities in total)
Functional Keywords	antibiotic resistance, bacterial antibiotic resistance, methicillin resistance, beta-lactamic antibiotics, mrsa, beta-lactamase, penicillin-binding protein
Biological source	STAPHYLOCOCCUS AUREUS More
Total number of polymer chains	2
Total formula weight	30108.92
Authors	Marrero, A.,Mallorqui-Fernandez, G.,Guevara, T.,Garcia-Castellanos, R.,Gomis-Ruth, F.X. (deposition date: 2006-06-27, release date: 2006-07-04, Last modification date: 2023-12-13)
Primary citation	Marrero, A.,Mallorqui-Fernandez, G.,Guevara, T.,Garcia-Castellanos, R.,Gomis-Ruth, F.X. Unbound and Acylated Structures of the Mecr1 Extracellular Antibiotic-Sensor Domain Provide Insights Into the Signal-Transduction System that Triggers Methicillin Resistance. J.Mol.Biol., 361:506-, 2006 Cited by PubMed: 16846613 DOI: 10.1016/J.JMB.2006.06.046 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation