1TIJ

3D Domain-swapped human cystatin C with amyloid-like intermolecular beta-sheets

Summary for 1TIJ
Related1A67 1CEW 1DVC 1G96 1N9J 1R4C 1RN7 1STF
DescriptorCystatin C (2 entities in total)
Functional Keywordshuman cystatin c dimer, 3d domain swapping, amyloid formation, inhibitor of c1 and c13 cysteine proteases, amyloid angiopathy, cerebral hemorrhage, hydrolase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P01034
Total number of polymer chains2
Total formula weight26730.28
Authors
Janowski, R.,Kozak, M.,Abrahamson, M.,Grubb, A.,Jaskolski, M. (deposition date: 2004-06-02, release date: 2005-07-19, Last modification date: 2011-07-13)
Primary citationAbrahamson, M.,Grubb, A.,Janowski, R.,Jaskolski, M.,Kozak, M.
3D domain-swapped human cystatin C with amyloidlike intermolecular beta-sheets.
Proteins, 61:570-578, 2005
PubMed: 16170782
DOI: 110.1002/prot.20633
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.03 Å)
Structure validation
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PDB entries from 2021-06-16